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The map label for this gene is atoD [H]

Identifier: 23100089

GI number: 23100089

Start: 2701549

End: 2702196

Strand: Reverse

Name: atoD [H]

Synonym: OB2634

Alternate gene names: 23100089

Gene position: 2702196-2701549 (Counterclockwise)

Preceding gene: 23100090

Following gene: 23100088

Centisome position: 74.43

GC content: 35.34

Gene sequence:

>648_bases
ATGGTAAATAAGCTAATTACATTTAATGAAAGTAAGAGTTTATTTCAAGATAAAATGACAATTATGTCGGGTGGATTTAT
GGGAGTAGGGACTCCAGAAAAAATAGTAGAAGCTATTTTAGAGTCTGAAGCAAATGAGTTAACGTTAATTACAAACGATA
CCTCATTTGAAAATAATGGTGTTGGACCATTGATTGCTAATAACCGTATTGCAAAAGTAGTAACATCACATATTGGCACG
AATCGTGCTACTGGAAGAAAAATGATATCTAAGGAACTCGAAGTTGAGCTGGTTCCTCAAGGTACGTTAGCTGAGAGAAT
TCGTGCTGGTGGAGCGGGACTAGGTGGTTTCTTGACACCTACTGGAGTTGGAACTGTCGTGGAAAAAGATAAACAAGTAA
TGCAAATAGAGGGGAAAAAATACATTCTAGAAACACCTTTAAAAGCTGATATAGCCATTATAAAAGCTTATAAAGCTGAC
AAAAGCGGTAATCTTGTATATCGACAATCTGCTAGGAATTTTAATCCATTAATTGCTCTAGCTGCTAAGCTAGTGATTGT
TCAAGCTGAACATATAGTAGAGATAGGGGAACTTGATCCAGAGTGTATCGTAACACCAAATGTATTAGTTGATAAAATTC
TAATATAA

Upstream 100 bases:

>100_bases
AGGTTCCACACTACATAATATTAAAATTTAGATAGTTGGCATGATTTTTGCTATATAGAATTGACAGCAGCAAAGAAAAA
TAACATAGGGGGTGGCTTTG

Downstream 100 bases:

>100_bases
AAAGAGGATGAAAAAATAATGAATAAAACATTGATAAGTGCCAAGGAACGAATTGCACAACGAGTGGCACAAGAATTACA
AAACGGAGATTTAGTTAATT

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit alpha

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MVNKLITFNESKSLFQDKMTIMSGGFMGVGTPEKIVEAILESEANELTLITNDTSFENNGVGPLIANNRIAKVVTSHIGT
NRATGRKMISKELEVELVPQGTLAERIRAGGAGLGGFLTPTGVGTVVEKDKQVMQIEGKKYILETPLKADIAIIKAYKAD
KSGNLVYRQSARNFNPLIALAAKLVIVQAEHIVEIGELDPECIVTPNVLVDKILI

Sequences:

>Translated_215_residues
MVNKLITFNESKSLFQDKMTIMSGGFMGVGTPEKIVEAILESEANELTLITNDTSFENNGVGPLIANNRIAKVVTSHIGT
NRATGRKMISKELEVELVPQGTLAERIRAGGAGLGGFLTPTGVGTVVEKDKQVMQIEGKKYILETPLKADIAIIKAYKAD
KSGNLVYRQSARNFNPLIALAAKLVIVQAEHIVEIGELDPECIVTPNVLVDKILI
>Mature_215_residues
MVNKLITFNESKSLFQDKMTIMSGGFMGVGTPEKIVEAILESEANELTLITNDTSFENNGVGPLIANNRIAKVVTSHIGT
NRATGRKMISKELEVELVPQGTLAERIRAGGAGLGGFLTPTGVGTVVEKDKQVMQIEGKKYILETPLKADIAIIKAYKAD
KSGNLVYRQSARNFNPLIALAAKLVIVQAEHIVEIGELDPECIVTPNVLVDKILI

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=216, Percent_Identity=40.7407407407407, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI11545841, Length=216, Percent_Identity=39.3518518518519, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1788551, Length=215, Percent_Identity=59.5348837209302, Blast_Score=279, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17531517, Length=219, Percent_Identity=36.5296803652968, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21358325, Length=217, Percent_Identity=40.0921658986175, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24655794, Length=217, Percent_Identity=40.0921658986175, Blast_Score=161, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23215; Mature: 23215

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKLITFNESKSLFQDKMTIMSGGFMGVGTPEKIVEAILESEANELTLITNDTSFENNG
CCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCC
VGPLIANNRIAKVVTSHIGTNRATGRKMISKELEVELVPQGTLAERIRAGGAGLGGFLTP
CCCEEECCHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCCCCC
TGVGTVVEKDKQVMQIEGKKYILETPLKADIAIIKAYKADKSGNLVYRQSARNFNPLIAL
CCCCHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHH
AAKLVIVQAEHIVEIGELDPECIVTPNVLVDKILI
HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCC
>Mature Secondary Structure
MVNKLITFNESKSLFQDKMTIMSGGFMGVGTPEKIVEAILESEANELTLITNDTSFENNG
CCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCC
VGPLIANNRIAKVVTSHIGTNRATGRKMISKELEVELVPQGTLAERIRAGGAGLGGFLTP
CCCEEECCHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHCCCCCCCCCCCC
TGVGTVVEKDKQVMQIEGKKYILETPLKADIAIIKAYKADKSGNLVYRQSARNFNPLIAL
CCCCHHHHCCCCEEEECCCEEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHH
AAKLVIVQAEHIVEIGELDPECIVTPNVLVDKILI
HHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]