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The map label for this gene is atoA [H]

Identifier: 23100088

GI number: 23100088

Start: 2700868

End: 2701530

Strand: Reverse

Name: atoA [H]

Synonym: OB2633

Alternate gene names: 23100088

Gene position: 2701530-2700868 (Counterclockwise)

Preceding gene: 23100089

Following gene: 23100087

Centisome position: 74.41

GC content: 34.39

Gene sequence:

>663_bases
ATGAATAAAACATTGATAAGTGCCAAGGAACGAATTGCACAACGAGTGGCACAAGAATTACAAAACGGAGATTTAGTTAA
TTTAGGAATCGGGCTTCCGACTTTAATTCCTAGTTATATTTCTAATAATATCCAAGTAACCTTTCAATCAGAGAATGGAT
TCATAGGGTTATCAAGTGTAGAAGATAATGTTAGTCCAGATTTAGTTAATGCTGGTGGTCAACCTGCAGGTATTAAACAA
GGTGGAGCGTTTTTTGATAGTGCATTCTCCTTCGAACTTATACGTGGTGGACATGTAGATGTAACTGTACTTGGAGGTCT
AGAAGTAGATCAAGAAGGTAATTTAGCCAATTGGATTATTCCTGGTAAGTTAGTTCCGGGAATGGGTGGTGCTATGGATT
TAGTAACAGGAGCAAAAAAAGTAATTATAGCAATGGAACATTTATCTAAAAAAGAAGAACCAAAAATAGTAAAGAAATGC
AAGTTACCTCTAACAGGTAGTAATGTGGTAGATATGATTGTTACTGAATTGGCGGTATTCAAAATTGAAAATAAGGAATT
AACATTAATAGAACTGATGCCAGGTGTTGGTGTAGATGAAGTACGTGATAAAACAGAAGCTGATTTTAATATTCACGAGG
ATATTAAAACAAAGATAAATTAG

Upstream 100 bases:

>100_bases
TGAACATATAGTAGAGATAGGGGAACTTGATCCAGAGTGTATCGTAACACCAAATGTATTAGTTGATAAAATTCTAATAT
AAAAAGAGGATGAAAAAATA

Downstream 100 bases:

>100_bases
ATAGGAGAGTTGGATGATGAAAGAAGTAGTGATTGTTAGTGCTGTCCGGACTGCTACAGGAAGTTTTATGGGGCTTTTAA
GTGATATACCTGCGACAAAA

Product: butyate-acetoacetate Ca-transferase large chain

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNKTLISAKERIAQRVAQELQNGDLVNLGIGLPTLIPSYISNNIQVTFQSENGFIGLSSVEDNVSPDLVNAGGQPAGIKQ
GGAFFDSAFSFELIRGGHVDVTVLGGLEVDQEGNLANWIIPGKLVPGMGGAMDLVTGAKKVIIAMEHLSKKEEPKIVKKC
KLPLTGSNVVDMIVTELAVFKIENKELTLIELMPGVGVDEVRDKTEADFNIHEDIKTKIN

Sequences:

>Translated_220_residues
MNKTLISAKERIAQRVAQELQNGDLVNLGIGLPTLIPSYISNNIQVTFQSENGFIGLSSVEDNVSPDLVNAGGQPAGIKQ
GGAFFDSAFSFELIRGGHVDVTVLGGLEVDQEGNLANWIIPGKLVPGMGGAMDLVTGAKKVIIAMEHLSKKEEPKIVKKC
KLPLTGSNVVDMIVTELAVFKIENKELTLIELMPGVGVDEVRDKTEADFNIHEDIKTKIN
>Mature_220_residues
MNKTLISAKERIAQRVAQELQNGDLVNLGIGLPTLIPSYISNNIQVTFQSENGFIGLSSVEDNVSPDLVNAGGQPAGIKQ
GGAFFDSAFSFELIRGGHVDVTVLGGLEVDQEGNLANWIIPGKLVPGMGGAMDLVTGAKKVIIAMEHLSKKEEPKIVKKC
KLPLTGSNVVDMIVTELAVFKIENKELTLIELMPGVGVDEVRDKTEADFNIHEDIKTKIN

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=207, Percent_Identity=51.207729468599, Blast_Score=204, Evalue=6e-53,
Organism=Homo sapiens, GI11545841, Length=213, Percent_Identity=47.4178403755869, Blast_Score=201, Evalue=5e-52,
Organism=Escherichia coli, GI1788552, Length=213, Percent_Identity=58.6854460093897, Blast_Score=270, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI17531517, Length=213, Percent_Identity=48.8262910798122, Blast_Score=199, Evalue=6e-52,
Organism=Drosophila melanogaster, GI21358325, Length=212, Percent_Identity=50.9433962264151, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24655794, Length=212, Percent_Identity=50.9433962264151, Blast_Score=207, Evalue=4e-54,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23650; Mature: 23650

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTLISAKERIAQRVAQELQNGDLVNLGIGLPTLIPSYISNNIQVTFQSENGFIGLSSV
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCEEEEEECCCCEEEECCC
EDNVSPDLVNAGGQPAGIKQGGAFFDSAFSFELIRGGHVDVTVLGGLEVDQEGNLANWII
CCCCCCCHHCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEECCEEECCCCCEEEEEE
PGKLVPGMGGAMDLVTGAKKVIIAMEHLSKKEEPKIVKKCKLPLTGSNVVDMIVTELAVF
CCCCCCCCCCHHHHHHCHHHHEEEHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHE
KIENKELTLIELMPGVGVDEVRDKTEADFNIHEDIKTKIN
EECCCCEEEEEECCCCCHHHHHCCCCCCCEEHHHHHHCCC
>Mature Secondary Structure
MNKTLISAKERIAQRVAQELQNGDLVNLGIGLPTLIPSYISNNIQVTFQSENGFIGLSSV
CCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCEEEEEECCCCEEEECCC
EDNVSPDLVNAGGQPAGIKQGGAFFDSAFSFELIRGGHVDVTVLGGLEVDQEGNLANWII
CCCCCCCHHCCCCCCCCCCCCCCHHHCCCEEEEEECCCEEEEEECCEEECCCCCEEEEEE
PGKLVPGMGGAMDLVTGAKKVIIAMEHLSKKEEPKIVKKCKLPLTGSNVVDMIVTELAVF
CCCCCCCCCCHHHHHHCHHHHEEEHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHE
KIENKELTLIELMPGVGVDEVRDKTEADFNIHEDIKTKIN
EECCCCEEEEEECCCCCHHHHHCCCCCCCEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]