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The map label for this gene is nprA [H]

Identifier: 23100052

GI number: 23100052

Start: 2656135

End: 2657391

Strand: Reverse

Name: nprA [H]

Synonym: OB2597

Alternate gene names: 23100052

Gene position: 2657391-2656135 (Counterclockwise)

Preceding gene: 23100055

Following gene: 23100051

Centisome position: 73.2

GC content: 29.91

Gene sequence:

>1257_bases
TTGGTGCATTTTGGTTATATGCTTAAATTTTATAGACAAGAACAAAAAATGACGCAATCCGAACTCGCCGATGGTATTAT
ATCCATTTCTTATTTATCAAAGATTGAAAATAAGTATGTCGACCCTCCAGAAGAAATAAAAGAATTACTATGTAAAAAAC
TTAAGATTAACAATTCGCAATTACAACAGATTCCCGTCTTAGATTTGTGTCAAAGATGGTTTCAAGCCTTGTTTTTAAGA
AATATAAATACTTCCGTCATCTTATATAGGCAGCTAAGTAGTCATAAACAATTAATTACTATTCAAGAAATGAATCATCT
CTTTGAAATTCATAAATTAAGATTCTATCTTATTCAAAATGATAAACAGAAGGTAGAAGAGCAATTTCAAAAACTTCAAC
TATTATCCCCGTATTTTACAGATGCAGAATCTTTCTATTGGTTAAAATTTATTGGGCAATACTATTTTTCGCGAGAGAAA
TATAAGAAGGCAATGGATTATTTTCAAAAGTCGATGGAGTATCTGGCTTATATAGAACGATCAAAGAAAGAAGAAAAACA
TGATATATTATATATGATTGCCTTATCTGCAAGCTATATTCGAGAAACCTATACTACAATCATCTATGCCCAACAAGCTT
TAATGTATTATCAGAAACAATATAACTTTAAACGAACAGCACAGTGTTATATATTATTGGGGATTTGCTATTCTAGAATG
CAAGACTATGAATCTGCGATGAATAGTTATCAACAAGCAAAAAAAATTGCTGATCGAATCAACAATATAAATTTACAAAC
TAAATGTTATCAAAATATAGGGAATTTATATTCTGAACGCAATCAATCGGAACAAGCTATAGCCTATTATAAGAAAAGTT
TTGTATTAAGAGCTGACCCGAAGAAACAGTTATACCCAATTATTGGATTAATGAAAGAGTATTATCGCATTGATGACCTA
TTCCATGCAAAAGAATGGTTAAATAAAGGACTAGCTATTGTAGAGGAAGATGATCAATCGATATATCGGTATGAGTTAGA
TGTGTATAGTCAATTAATAAATAAGGTATATTCAAGCTTAGAAAAAATTATTTTGGAGAAAATTATACCATTTGTTGATG
AGAAACAATTGTATTTGAAGAAAACAGCTTATTTAGAAATATTGGCTACACATTATTATAGTCAAAGAAAATACAAACTA
GCAGCGACCTACTACAATCATGCTCTTCATACAACGAAAGCTGTTGAAGGGAGGTGA

Upstream 100 bases:

>100_bases
ATATTTGGCTAATAAATCTAAATATTGAGATAAAAATAAATGGTGATTTTTTACATTTTATGGTAAGATAAATAAAAATT
CATATAGAGAGGGGATATGA

Downstream 100 bases:

>100_bases
ATTAGATGAAAAAGATCAATTATCTTTTAGGAATCGTATTTCTGCTTACCCTTATGGTAATCGTTCCTTCGAATGTAGGT
GCGGAGAAAGTCGATTTAAT

Product: transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MVHFGYMLKFYRQEQKMTQSELADGIISISYLSKIENKYVDPPEEIKELLCKKLKINNSQLQQIPVLDLCQRWFQALFLR
NINTSVILYRQLSSHKQLITIQEMNHLFEIHKLRFYLIQNDKQKVEEQFQKLQLLSPYFTDAESFYWLKFIGQYYFSREK
YKKAMDYFQKSMEYLAYIERSKKEEKHDILYMIALSASYIRETYTTIIYAQQALMYYQKQYNFKRTAQCYILLGICYSRM
QDYESAMNSYQQAKKIADRINNINLQTKCYQNIGNLYSERNQSEQAIAYYKKSFVLRADPKKQLYPIIGLMKEYYRIDDL
FHAKEWLNKGLAIVEEDDQSIYRYELDVYSQLINKVYSSLEKIILEKIIPFVDEKQLYLKKTAYLEILATHYYSQRKYKL
AATYYNHALHTTKAVEGR

Sequences:

>Translated_418_residues
MVHFGYMLKFYRQEQKMTQSELADGIISISYLSKIENKYVDPPEEIKELLCKKLKINNSQLQQIPVLDLCQRWFQALFLR
NINTSVILYRQLSSHKQLITIQEMNHLFEIHKLRFYLIQNDKQKVEEQFQKLQLLSPYFTDAESFYWLKFIGQYYFSREK
YKKAMDYFQKSMEYLAYIERSKKEEKHDILYMIALSASYIRETYTTIIYAQQALMYYQKQYNFKRTAQCYILLGICYSRM
QDYESAMNSYQQAKKIADRINNINLQTKCYQNIGNLYSERNQSEQAIAYYKKSFVLRADPKKQLYPIIGLMKEYYRIDDL
FHAKEWLNKGLAIVEEDDQSIYRYELDVYSQLINKVYSSLEKIILEKIIPFVDEKQLYLKKTAYLEILATHYYSQRKYKL
AATYYNHALHTTKAVEGR
>Mature_418_residues
MVHFGYMLKFYRQEQKMTQSELADGIISISYLSKIENKYVDPPEEIKELLCKKLKINNSQLQQIPVLDLCQRWFQALFLR
NINTSVILYRQLSSHKQLITIQEMNHLFEIHKLRFYLIQNDKQKVEEQFQKLQLLSPYFTDAESFYWLKFIGQYYFSREK
YKKAMDYFQKSMEYLAYIERSKKEEKHDILYMIALSASYIRETYTTIIYAQQALMYYQKQYNFKRTAQCYILLGICYSRM
QDYESAMNSYQQAKKIADRINNINLQTKCYQNIGNLYSERNQSEQAIAYYKKSFVLRADPKKQLYPIIGLMKEYYRIDDL
FHAKEWLNKGLAIVEEDDQSIYRYELDVYSQLINKVYSSLEKIILEKIIPFVDEKQLYLKKTAYLEILATHYYSQRKYKL
AATYYNHALHTTKAVEGR

Specific function: Activates the transcription of nprS by about five fold. May bind to the upstream region of nprS promoter [H]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01381 HTH_3; PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 50438; Mature: 50438

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION L=RR ; PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHFGYMLKFYRQEQKMTQSELADGIISISYLSKIENKYVDPPEEIKELLCKKLKINNSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
LQQIPVLDLCQRWFQALFLRNINTSVILYRQLSSHKQLITIQEMNHLFEIHKLRFYLIQN
HHCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHEECC
DKQKVEEQFQKLQLLSPYFTDAESFYWLKFIGQYYFSREKYKKAMDYFQKSMEYLAYIER
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKEEKHDILYMIALSASYIRETYTTIIYAQQALMYYQKQYNFKRTAQCYILLGICYSRM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QDYESAMNSYQQAKKIADRINNINLQTKCYQNIGNLYSERNQSEQAIAYYKKSFVLRADP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
KKQLYPIIGLMKEYYRIDDLFHAKEWLNKGLAIVEEDDQSIYRYELDVYSQLINKVYSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EKIILEKIIPFVDEKQLYLKKTAYLEILATHYYSQRKYKLAATYYNHALHTTKAVEGR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVHFGYMLKFYRQEQKMTQSELADGIISISYLSKIENKYVDPPEEIKELLCKKLKINNSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
LQQIPVLDLCQRWFQALFLRNINTSVILYRQLSSHKQLITIQEMNHLFEIHKLRFYLIQN
HHCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHEECC
DKQKVEEQFQKLQLLSPYFTDAESFYWLKFIGQYYFSREKYKKAMDYFQKSMEYLAYIER
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKEEKHDILYMIALSASYIRETYTTIIYAQQALMYYQKQYNFKRTAQCYILLGICYSRM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QDYESAMNSYQQAKKIADRINNINLQTKCYQNIGNLYSERNQSEQAIAYYKKSFVLRADP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCC
KKQLYPIIGLMKEYYRIDDLFHAKEWLNKGLAIVEEDDQSIYRYELDVYSQLINKVYSSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EKIILEKIIPFVDEKQLYLKKTAYLEILATHYYSQRKYKLAATYYNHALHTTKAVEGR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2203733 [H]