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The map label for this gene is glpD [H]

Identifier: 23099926

GI number: 23099926

Start: 2528200

End: 2529861

Strand: Reverse

Name: glpD [H]

Synonym: OB2471

Alternate gene names: 23099926

Gene position: 2529861-2528200 (Counterclockwise)

Preceding gene: 23099927

Following gene: 23099925

Centisome position: 69.68

GC content: 36.16

Gene sequence:

>1662_bases
ATGAATCAATTTTCAAGTTATAGAAGAAAAGATACATTAGATGCTTTACAAAACGAAAAATTAGACTTATTAGTGATTGG
CGGAGGTATTACTGGAGCAGGTATTTCCCTGGATGCTACAACTCGTGGTTTAAATACAGGCCTAATCGAAATGCAAGACT
TTGCTGCTGGTACATCTAGTCGATCCACTAAGCTAGTTCATGGTGGACTACGTTATTTACAGCAATTTGAAGTGAAGATG
GTAGCTGAAGTAGGGAAAGAAAGAGCAATTGTATATGAAAATGGGCCACATGTTACAACCCCAGAATGGATGCTACTACC
ATTCCATAAGGGAAGTACACTTGGACCATTTACTTCAAATATTGGATTAAGAGTTTATGACTTTTTAGCAGGTGTTAAAA
AAGACGAACGTAGAGTAATGTTTAAGCCAAAAGAAGTAATGGAACGTGAACCATTAATTAAACAAGATGAATTACGTGGT
GGCGGATACTATGTGGAATATAAAACCGATGATGCTCGTTTAACAATTGAAGTTATGAAGAAGGCTGTTGAAGAGGGTGT
TCATGCGATAAACTACACCAAAGCGGTTGAATTTATTTATGAAGATAGTAAAGTTGTCGGTGTTGTTGCAGAAGATTTAA
TTACTGGGGAAAAACGAAAAATTTATGCAAAAAAAATCATTAATGCTGGTGGACCATGGGTGGATGATGTACGTGAATTA
GATGGTTCGAAAAAAGGTAAGACGCTTCACTTAACCAAAGGTGTCCATCTTGTTTTTGATCATAACACATTTCCTTTACA
ACAAGCAGTGTACTTTGATTCACCTGATGGTCGTATGATCTTTGCTATTCCACGAGATGGAAAAACGTATGTTGGTACGA
CGGATACAACTTATGAAGGAGATATAGCTCATCCAGTGATGACGGAAGATGATCGTGACTATTTATTAAAAGCTATTGCT
TATATGTTCCCTTCTCTACAGTTAAAACCAGAAGATGTGGAATCAAGTTGGGCGGGATTACGTCCACTAATTGCACAAGA
GGGCGCAACTAGTCCGAGTGAAATTTCACGTAAAGATGAAATTTTCCAATCAGATTCTGGACTGTTATCTATGGCAGGCG
GAAAATTAACTGGATATCGAAAAATGGCCCAACACGCAGTAGATCTAGTAACGAAACAGTTAAAAGAAGAAGAAAATATC
CTTTATACCGATAGTCAAACCAAACATCTACCGATATCCGGTGGCGATGTTGGTGGATCTAAAGGATTTGAAGCATTTAA
AAAAGATAAGCAAAAACAAGCTATTCAATTAGGCCTTTCAGAACAAGAAGCACTTCAAATGATTCAGCGTTATGGATCAA
ATGTAGAGATTTTATTAGATATTTATAAAAATCAAAAAGAAGAAGCGAATAAGTACGATATTGACCCAATTGTATTTGCA
GAATTGGTATATGCAATAGAATTTGAACTTGCATATAAACCGGTAGATTTCTTTATCCGTCGAACTGGTGCATTATTCTT
CCAACGTCCATGGGTAGAAGCGCATATGGATAAAGTTCTTCCATATATGAAAGAGAAATTACAATATACGGATGAACAGT
TAAATGAGTATACAACTCAGCTAAAAGAATTATTATACGAAACAACTAATCCCGTTAAATAA

Upstream 100 bases:

>100_bases
TACCAGTTATTTTGCGGTTTTTTCTTTTTCTCTACATGATTATATTTAAAAACGGGTAAAGTGAATATAAGAATAACTAA
ACAACGGGGAGTGTAATATA

Downstream 100 bases:

>100_bases
TATTTACTGAAGTGTATGAATCAAGGCTTTTTGTACGTATAACAGCATAAAAAAGCATCTCCAACGTCGTAGTAGAAATA
TAATGGCGTTTTAGGAGGTG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MNQFSSYRRKDTLDALQNEKLDLLVIGGGITGAGISLDATTRGLNTGLIEMQDFAAGTSSRSTKLVHGGLRYLQQFEVKM
VAEVGKERAIVYENGPHVTTPEWMLLPFHKGSTLGPFTSNIGLRVYDFLAGVKKDERRVMFKPKEVMEREPLIKQDELRG
GGYYVEYKTDDARLTIEVMKKAVEEGVHAINYTKAVEFIYEDSKVVGVVAEDLITGEKRKIYAKKIINAGGPWVDDVREL
DGSKKGKTLHLTKGVHLVFDHNTFPLQQAVYFDSPDGRMIFAIPRDGKTYVGTTDTTYEGDIAHPVMTEDDRDYLLKAIA
YMFPSLQLKPEDVESSWAGLRPLIAQEGATSPSEISRKDEIFQSDSGLLSMAGGKLTGYRKMAQHAVDLVTKQLKEEENI
LYTDSQTKHLPISGGDVGGSKGFEAFKKDKQKQAIQLGLSEQEALQMIQRYGSNVEILLDIYKNQKEEANKYDIDPIVFA
ELVYAIEFELAYKPVDFFIRRTGALFFQRPWVEAHMDKVLPYMKEKLQYTDEQLNEYTTQLKELLYETTNPVK

Sequences:

>Translated_553_residues
MNQFSSYRRKDTLDALQNEKLDLLVIGGGITGAGISLDATTRGLNTGLIEMQDFAAGTSSRSTKLVHGGLRYLQQFEVKM
VAEVGKERAIVYENGPHVTTPEWMLLPFHKGSTLGPFTSNIGLRVYDFLAGVKKDERRVMFKPKEVMEREPLIKQDELRG
GGYYVEYKTDDARLTIEVMKKAVEEGVHAINYTKAVEFIYEDSKVVGVVAEDLITGEKRKIYAKKIINAGGPWVDDVREL
DGSKKGKTLHLTKGVHLVFDHNTFPLQQAVYFDSPDGRMIFAIPRDGKTYVGTTDTTYEGDIAHPVMTEDDRDYLLKAIA
YMFPSLQLKPEDVESSWAGLRPLIAQEGATSPSEISRKDEIFQSDSGLLSMAGGKLTGYRKMAQHAVDLVTKQLKEEENI
LYTDSQTKHLPISGGDVGGSKGFEAFKKDKQKQAIQLGLSEQEALQMIQRYGSNVEILLDIYKNQKEEANKYDIDPIVFA
ELVYAIEFELAYKPVDFFIRRTGALFFQRPWVEAHMDKVLPYMKEKLQYTDEQLNEYTTQLKELLYETTNPVK
>Mature_553_residues
MNQFSSYRRKDTLDALQNEKLDLLVIGGGITGAGISLDATTRGLNTGLIEMQDFAAGTSSRSTKLVHGGLRYLQQFEVKM
VAEVGKERAIVYENGPHVTTPEWMLLPFHKGSTLGPFTSNIGLRVYDFLAGVKKDERRVMFKPKEVMEREPLIKQDELRG
GGYYVEYKTDDARLTIEVMKKAVEEGVHAINYTKAVEFIYEDSKVVGVVAEDLITGEKRKIYAKKIINAGGPWVDDVREL
DGSKKGKTLHLTKGVHLVFDHNTFPLQQAVYFDSPDGRMIFAIPRDGKTYVGTTDTTYEGDIAHPVMTEDDRDYLLKAIA
YMFPSLQLKPEDVESSWAGLRPLIAQEGATSPSEISRKDEIFQSDSGLLSMAGGKLTGYRKMAQHAVDLVTKQLKEEENI
LYTDSQTKHLPISGGDVGGSKGFEAFKKDKQKQAIQLGLSEQEALQMIQRYGSNVEILLDIYKNQKEEANKYDIDPIVFA
ELVYAIEFELAYKPVDFFIRRTGALFFQRPWVEAHMDKVLPYMKEKLQYTDEQLNEYTTQLKELLYETTNPVK

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=564, Percent_Identity=31.2056737588652, Blast_Score=258, Evalue=9e-69,
Organism=Homo sapiens, GI285002231, Length=564, Percent_Identity=31.2056737588652, Blast_Score=258, Evalue=9e-69,
Organism=Escherichia coli, GI2367226, Length=502, Percent_Identity=30.4780876494024, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1788574, Length=368, Percent_Identity=25.2717391304348, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17509253, Length=397, Percent_Identity=35.5163727959698, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI115534726, Length=557, Percent_Identity=30.7001795332136, Blast_Score=214, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322036, Length=566, Percent_Identity=30.0353356890459, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI161077125, Length=563, Percent_Identity=31.4387211367673, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24653942, Length=563, Percent_Identity=31.4387211367673, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24653944, Length=563, Percent_Identity=31.4387211367673, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI20130025, Length=563, Percent_Identity=31.4387211367673, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586295, Length=559, Percent_Identity=27.3703041144902, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19921278, Length=563, Percent_Identity=26.9982238010657, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550977, Length=414, Percent_Identity=25.1207729468599, Blast_Score=102, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62461; Mature: 62461

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFSSYRRKDTLDALQNEKLDLLVIGGGITGAGISLDATTRGLNTGLIEMQDFAAGTSS
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEHHHCCCCCC
RSTKLVHGGLRYLQQFEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHKGSTLGPFTSN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCC
IGLRVYDFLAGVKKDERRVMFKPKEVMEREPLIKQDELRGGGYYVEYKTDDARLTIEVMK
CCHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCCHHCCCCCCEEEEEECCCCEEEHHHHH
KAVEEGVHAINYTKAVEFIYEDSKVVGVVAEDLITGEKRKIYAKKIINAGGPWVDDVREL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHC
DGSKKGKTLHLTKGVHLVFDHNTFPLQQAVYFDSPDGRMIFAIPRDGKTYVGTTDTTYEG
CCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCC
DIAHPVMTEDDRDYLLKAIAYMFPSLQLKPEDVESSWAGLRPLIAQEGATSPSEISRKDE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHCCCCCCHHHHHHHHH
IFQSDSGLLSMAGGKLTGYRKMAQHAVDLVTKQLKEEENILYTDSQTKHLPISGGDVGGS
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCC
KGFEAFKKDKQKQAIQLGLSEQEALQMIQRYGSNVEILLDIYKNQKEEANKYDIDPIVFA
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEHHCCHHHCCCCCCCHHHHH
ELVYAIEFELAYKPVDFFIRRTGALFFQRPWVEAHMDKVLPYMKEKLQYTDEQLNEYTTQ
HHHHHHHHHEECCHHHHHHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKELLYETTNPVK
HHHHHHHCCCCCC
>Mature Secondary Structure
MNQFSSYRRKDTLDALQNEKLDLLVIGGGITGAGISLDATTRGLNTGLIEMQDFAAGTSS
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCEEEHHHCCCCCC
RSTKLVHGGLRYLQQFEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHKGSTLGPFTSN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCC
IGLRVYDFLAGVKKDERRVMFKPKEVMEREPLIKQDELRGGGYYVEYKTDDARLTIEVMK
CCHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCCHHCCCCCCEEEEEECCCCEEEHHHHH
KAVEEGVHAINYTKAVEFIYEDSKVVGVVAEDLITGEKRKIYAKKIINAGGPWVDDVREL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHC
DGSKKGKTLHLTKGVHLVFDHNTFPLQQAVYFDSPDGRMIFAIPRDGKTYVGTTDTTYEG
CCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCC
DIAHPVMTEDDRDYLLKAIAYMFPSLQLKPEDVESSWAGLRPLIAQEGATSPSEISRKDE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHCCCCCCHHHHHHHHH
IFQSDSGLLSMAGGKLTGYRKMAQHAVDLVTKQLKEEENILYTDSQTKHLPISGGDVGGS
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCC
KGFEAFKKDKQKQAIQLGLSEQEALQMIQRYGSNVEILLDIYKNQKEEANKYDIDPIVFA
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEHHCCHHHCCCCCCCHHHHH
ELVYAIEFELAYKPVDFFIRRTGALFFQRPWVEAHMDKVLPYMKEKLQYTDEQLNEYTTQ
HHHHHHHHHEECCHHHHHHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKELLYETTNPVK
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]