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The map label for this gene is exuR [H]

Identifier: 23099630

GI number: 23099630

Start: 2210567

End: 2211172

Strand: Reverse

Name: exuR [H]

Synonym: OB2175

Alternate gene names: 23099630

Gene position: 2211172-2210567 (Counterclockwise)

Preceding gene: 23099631

Following gene: 23099629

Centisome position: 60.9

GC content: 32.01

Gene sequence:

>606_bases
ATGACAGTAACAAATAAACAAAAGGTTTATCAAAGCGTAATTAAAGAGTTACAGCGCTATATAGAGATAAACCATTTAAA
TGCCGGGGACAAGCTTCCTTCCGAAAGAGAGCTTTCAGATAAACTTAATGCTGGAAGATCTTCCATAAGAGAAGCTTTAC
GAGCATTAGAATTAATTGGGTTAATAGAAACAAGACATGGAGAAGGTACATTTCTTAATTCTTATCAATCCTTTCAAACA
GTTGAACTTCTATCTTCTTTCATCTTGACTCAAAATAATATAAAGCATGAAATACCTTGGACTAAACAAATCATTGAAAA
AGAAGCAACTAAGCTTGCGGTGGAAAATCTTACTGAAAAAGATATAGAGGAACTAGAGAAAATAGATCAATTGTATGAAG
CAGATGATTTACATCATAAATTCTTTTCCTTTTTGTTAAAAAGGACGAATAATTTGTTAATGGATCGAATTTGGATGCTC
TTAGAAGAGTTCTCATCTACTGTCCCAAAGCAGTATTATATCGATGGATTCTACCCTCGATTGATTAAATCTATTCGTGA
TAAAGACTATGAGTCAATTGAATGCATTTTTACAAATCCTTCTTAA

Upstream 100 bases:

>100_bases
AATGAGTACTGGAGTCGCTAGAATGAATGTAGATCCTGAAGAAGTAGCAGAAAAGACAAGGAAATTAACACAGCAGGAAA
AATAAGGAGTGAATCCCCGC

Downstream 100 bases:

>100_bases
AAACAAGTTGAACTAATTTTTTATAGATACTCGACGAGTTTCGATACTTTTTTCAGTTAATTATCTATATAGTAATTTTA
TATGCATGTCCAGGTGTTTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTVTNKQKVYQSVIKELQRYIEINHLNAGDKLPSERELSDKLNAGRSSIREALRALELIGLIETRHGEGTFLNSYQSFQT
VELLSSFILTQNNIKHEIPWTKQIIEKEATKLAVENLTEKDIEELEKIDQLYEADDLHHKFFSFLLKRTNNLLMDRIWML
LEEFSSTVPKQYYIDGFYPRLIKSIRDKDYESIECIFTNPS

Sequences:

>Translated_201_residues
MTVTNKQKVYQSVIKELQRYIEINHLNAGDKLPSERELSDKLNAGRSSIREALRALELIGLIETRHGEGTFLNSYQSFQT
VELLSSFILTQNNIKHEIPWTKQIIEKEATKLAVENLTEKDIEELEKIDQLYEADDLHHKFFSFLLKRTNNLLMDRIWML
LEEFSSTVPKQYYIDGFYPRLIKSIRDKDYESIECIFTNPS
>Mature_200_residues
TVTNKQKVYQSVIKELQRYIEINHLNAGDKLPSERELSDKLNAGRSSIREALRALELIGLIETRHGEGTFLNSYQSFQTV
ELLSSFILTQNNIKHEIPWTKQIIEKEATKLAVENLTEKDIEELEKIDQLYEADDLHHKFFSFLLKRTNNLLMDRIWMLL
EEFSSTVPKQYYIDGFYPRLIKSIRDKDYESIECIFTNPS

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=128, Percent_Identity=31.25, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790780, Length=132, Percent_Identity=28.7878787878788, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 23634; Mature: 23503

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTNKQKVYQSVIKELQRYIEINHLNAGDKLPSERELSDKLNAGRSSIREALRALELIG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
LIETRHGEGTFLNSYQSFQTVELLSSFILTQNNIKHEIPWTKQIIEKEATKLAVENLTEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
DIEELEKIDQLYEADDLHHKFFSFLLKRTNNLLMDRIWMLLEEFSSTVPKQYYIDGFYPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHH
LIKSIRDKDYESIECIFTNPS
HHHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure 
TVTNKQKVYQSVIKELQRYIEINHLNAGDKLPSERELSDKLNAGRSSIREALRALELIG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
LIETRHGEGTFLNSYQSFQTVELLSSFILTQNNIKHEIPWTKQIIEKEATKLAVENLTEK
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
DIEELEKIDQLYEADDLHHKFFSFLLKRTNNLLMDRIWMLLEEFSSTVPKQYYIDGFYPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHH
LIKSIRDKDYESIECIFTNPS
HHHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA