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The map label for this gene is accD

Identifier: 23099629

GI number: 23099629

Start: 2209592

End: 2210452

Strand: Reverse

Name: accD

Synonym: OB2174

Alternate gene names: 23099629

Gene position: 2210452-2209592 (Counterclockwise)

Preceding gene: 23099630

Following gene: 23099628

Centisome position: 60.89

GC content: 38.44

Gene sequence:

>861_bases
TTGCTAAAAGATCTCTTCGGCAAGCGGAAAAAATATGCATCCATTCCAAGTGAAAAAGCGAAGATGGATGTGCCAGAGGG
TTTAATGCAGAAATGTTCAAACTGCAAAAAGATATACTACCGTAAAGAAATGGTAAAAGCTTTACAAGTATGCCCTAATT
GTGATTATCATCATCCTATGACAGCATGGGACCGAATCGACAGTTTATTTGACAATGGAACATTTGAGGAATGGGATAAA
GAGATTACATCAGCAAATCCTTTAGATTTTCCTGAATATGAAAGTAAGATTGCAAAGGATCGTGAAAAAACGTCTCTTTC
TGAAGGTGTGGTTACGGGAAAAGGAAAGGTAAACAACGTTCAGATTGCCTTTGCAGTGATGGATTCTCACTTTCGAATGG
GAAGTATGGGGTCTGCAATTGGCGAAAAAATTACAAGAGCTATTGAAGCAGCAAGAGAAGAATCAATTCCATTTGTAATT
TTTACTGCTTCTGGTGGTGCTCGAATGCAAGAAGGCGTTTTAAGTTTAATGCAGATGGCTAAAACATCTTTTGCAGTTAA
AAGATTTCGTGACAGTGGAGGGTTGATGATCTCTGTAATGACACACCCGACTACTGGTGGTGTTTCAGCAAGTTTCGCTT
CCATTGGAGATTATAATTTTGCAGAACCTGGAGCATTAATTGGTTTTGCAGGTAGAAGGATTATTGAACAAACTATTCGC
GAGAAGTTACCAAGTGATTTTCAAACTGCAGAGTTTCAACTACACCATGGACAAGTTGATAAAGTAATCCATAGACAGGA
CATGAATGATACACTCGGCAAGTTGCTTAAAATGCATATGGATGGGAGACAACTTAAATGA

Upstream 100 bases:

>100_bases
AATTTTTTATAGATACTCGACGAGTTTCGATACTTTTTTCAGTTAATTATCTATATAGTAATTTTATATGCATGTCCAGG
TGTTTAAAGGGGGAATAAAC

Downstream 100 bases:

>100_bases
CTCCAATACTTGATTTTGAGAAACCAATTGTAAATCTTAAAGAAAAAATAGTTGAATTAAAATCGTTTACGGAAAATAGT
GAGATCGATTTAACGAAAGA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLKDLFGKRKKYASIPSEKAKMDVPEGLMQKCSNCKKIYYRKEMVKALQVCPNCDYHHPMTAWDRIDSLFDNGTFEEWDK
EITSANPLDFPEYESKIAKDREKTSLSEGVVTGKGKVNNVQIAFAVMDSHFRMGSMGSAIGEKITRAIEAAREESIPFVI
FTASGGARMQEGVLSLMQMAKTSFAVKRFRDSGGLMISVMTHPTTGGVSASFASIGDYNFAEPGALIGFAGRRIIEQTIR
EKLPSDFQTAEFQLHHGQVDKVIHRQDMNDTLGKLLKMHMDGRQLK

Sequences:

>Translated_286_residues
MLKDLFGKRKKYASIPSEKAKMDVPEGLMQKCSNCKKIYYRKEMVKALQVCPNCDYHHPMTAWDRIDSLFDNGTFEEWDK
EITSANPLDFPEYESKIAKDREKTSLSEGVVTGKGKVNNVQIAFAVMDSHFRMGSMGSAIGEKITRAIEAAREESIPFVI
FTASGGARMQEGVLSLMQMAKTSFAVKRFRDSGGLMISVMTHPTTGGVSASFASIGDYNFAEPGALIGFAGRRIIEQTIR
EKLPSDFQTAEFQLHHGQVDKVIHRQDMNDTLGKLLKMHMDGRQLK
>Mature_286_residues
MLKDLFGKRKKYASIPSEKAKMDVPEGLMQKCSNCKKIYYRKEMVKALQVCPNCDYHHPMTAWDRIDSLFDNGTFEEWDK
EITSANPLDFPEYESKIAKDREKTSLSEGVVTGKGKVNNVQIAFAVMDSHFRMGSMGSAIGEKITRAIEAAREESIPFVI
FTASGGARMQEGVLSLMQMAKTSFAVKRFRDSGGLMISVMTHPTTGGVSASFASIGDYNFAEPGALIGFAGRRIIEQTIR
EKLPSDFQTAEFQLHHGQVDKVIHRQDMNDTLGKLLKMHMDGRQLK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=44.043321299639, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_OCEIH (Q8EPD4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693095.1
- ProteinModelPortal:   Q8EPD4
- GeneID:   1015924
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2174
- NMPDR:   fig|221109.1.peg.2172
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- BioCyc:   OIHE221109:OB2174-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32004; Mature: 32004

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDLFGKRKKYASIPSEKAKMDVPEGLMQKCSNCKKIYYRKEMVKALQVCPNCDYHHPM
CCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TAWDRIDSLFDNGTFEEWDKEITSANPLDFPEYESKIAKDREKTSLSEGVVTGKGKVNNV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCE
QIAFAVMDSHFRMGSMGSAIGEKITRAIEAAREESIPFVIFTASGGARMQEGVLSLMQMA
EEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
KTSFAVKRFRDSGGLMISVMTHPTTGGVSASFASIGDYNFAEPGALIGFAGRRIIEQTIR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EKLPSDFQTAEFQLHHGQVDKVIHRQDMNDTLGKLLKMHMDGRQLK
HHCCCCCCHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLKDLFGKRKKYASIPSEKAKMDVPEGLMQKCSNCKKIYYRKEMVKALQVCPNCDYHHPM
CCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TAWDRIDSLFDNGTFEEWDKEITSANPLDFPEYESKIAKDREKTSLSEGVVTGKGKVNNV
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCE
QIAFAVMDSHFRMGSMGSAIGEKITRAIEAAREESIPFVIFTASGGARMQEGVLSLMQMA
EEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
KTSFAVKRFRDSGGLMISVMTHPTTGGVSASFASIGDYNFAEPGALIGFAGRRIIEQTIR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EKLPSDFQTAEFQLHHGQVDKVIHRQDMNDTLGKLLKMHMDGRQLK
HHCCCCCCHHHEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376