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The map label for this gene is accA

Identifier: 23099628

GI number: 23099628

Start: 2208642

End: 2209595

Strand: Reverse

Name: accA

Synonym: OB2173

Alternate gene names: 23099628

Gene position: 2209595-2208642 (Counterclockwise)

Preceding gene: 23099629

Following gene: 23099627

Centisome position: 60.86

GC content: 37.0

Gene sequence:

>954_bases
ATGACTCCAATACTTGATTTTGAGAAACCAATTGTAAATCTTAAAGAAAAAATAGTTGAATTAAAATCGTTTACGGAAAA
TAGTGAGATCGATTTAACGAAAGAGATTGAAACCTTAGAAGAAAGACTAGCCAGACTGGAAGAAGATATTTATGGGAATT
TAAAACCATGGAATAGAGTTCAGATGGCTAGACATCCTGATCGTCCTACAACAATGGATTATATTGAACGGATATTTACT
GACTTTATTGAGTTTCATGGTGACCGTTTTTATGGTGAAGACGAAGCGATAATATCAGGTATTGGATATTATAAAGATTC
CCCAGTCACTGTAATAGGACATCAGCGCGGGAAGGACACTAAAGAAAATATCCGCAGGAACTTTGGAATGCCACATCCTG
AGGGATATCGTAAGGCATTACGGCATATGCAACAAGCAGAGAAGTTTAATAGACCAATTATCACGTTTATTGATACTAAA
GGTGCTTATCCTGGTAAAGCGGCTGAAGAAAGAGGGCAAAGTGAAGCGATCGCCAAAAATTTGATGGAGATGGCAGGTTT
ACAAGTTCCCATTATATGTATTGTTATTGGTGAAGGTGGTAGTGGGGGTGCACTTGGTCTAGGTGTTGGAAATCATATTC
ATATGTTAGAGAACTCTACATACTCTGTGATTTCACCTGAAGGTGCTGCAGCAATTTTATGGAAGGATTCGACTCAAGCT
AAAAAAGCAGCTGAAACCATGAAAATTACTGCGCCTGACTTAAAGGAATTAGGCATCATAGATCAAGTGATTTCCGAACC
AAGAGGTGGAGCTCATCGTGATGTAGATTCTCAAGCAGAACTAATTGATAATATAATAAAACAATCTTTAGTTGAATTAA
TGTTGCTTTCATCAGAGGAGTTAGTAGATAAAAGATGGGAAAAATATAAACAAATGGGGACATTCATGTCTTAA

Upstream 100 bases:

>100_bases
AACTACACCATGGACAAGTTGATAAAGTAATCCATAGACAGGACATGAATGATACACTCGGCAAGTTGCTTAAAATGCAT
ATGGATGGGAGACAACTTAA

Downstream 100 bases:

>100_bases
TAAAACAAAGGCTGATAAAAATTTTTATATCAGCCTTTTATTTTTGCGAGAAATTTTGTAAAATTAGTAGGTTGTGGGGT
TTATGATTGATATTTAAAGA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTPILDFEKPIVNLKEKIVELKSFTENSEIDLTKEIETLEERLARLEEDIYGNLKPWNRVQMARHPDRPTTMDYIERIFT
DFIEFHGDRFYGEDEAIISGIGYYKDSPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRHMQQAEKFNRPIITFIDTK
GAYPGKAAEERGQSEAIAKNLMEMAGLQVPIICIVIGEGGSGGALGLGVGNHIHMLENSTYSVISPEGAAAILWKDSTQA
KKAAETMKITAPDLKELGIIDQVISEPRGGAHRDVDSQAELIDNIIKQSLVELMLLSSEELVDKRWEKYKQMGTFMS

Sequences:

>Translated_317_residues
MTPILDFEKPIVNLKEKIVELKSFTENSEIDLTKEIETLEERLARLEEDIYGNLKPWNRVQMARHPDRPTTMDYIERIFT
DFIEFHGDRFYGEDEAIISGIGYYKDSPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRHMQQAEKFNRPIITFIDTK
GAYPGKAAEERGQSEAIAKNLMEMAGLQVPIICIVIGEGGSGGALGLGVGNHIHMLENSTYSVISPEGAAAILWKDSTQA
KKAAETMKITAPDLKELGIIDQVISEPRGGAHRDVDSQAELIDNIIKQSLVELMLLSSEELVDKRWEKYKQMGTFMS
>Mature_316_residues
TPILDFEKPIVNLKEKIVELKSFTENSEIDLTKEIETLEERLARLEEDIYGNLKPWNRVQMARHPDRPTTMDYIERIFTD
FIEFHGDRFYGEDEAIISGIGYYKDSPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRHMQQAEKFNRPIITFIDTKG
AYPGKAAEERGQSEAIAKNLMEMAGLQVPIICIVIGEGGSGGALGLGVGNHIHMLENSTYSVISPEGAAAILWKDSTQAK
KAAETMKITAPDLKELGIIDQVISEPRGGAHRDVDSQAELIDNIIKQSLVELMLLSSEELVDKRWEKYKQMGTFMS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=53.3546325878594, Blast_Score=344, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_OCEIH (Q8EPD5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693094.1
- ProteinModelPortal:   Q8EPD5
- SMR:   Q8EPD5
- GeneID:   1017625
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2173
- NMPDR:   fig|221109.1.peg.2171
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   OIHE221109:OB2173-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35751; Mature: 35620

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPILDFEKPIVNLKEKIVELKSFTENSEIDLTKEIETLEERLARLEEDIYGNLKPWNRV
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QMARHPDRPTTMDYIERIFTDFIEFHGDRFYGEDEAIISGIGYYKDSPVTVIGHQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCH
KENIRRNFGMPHPEGYRKALRHMQQAEKFNRPIITFIDTKGAYPGKAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LMEMAGLQVPIICIVIGEGGSGGALGLGVGNHIHMLENSTYSVISPEGAAAILWKDSTQA
HHHHCCCCEEEEEEEEECCCCCCEEEECCCCEEEEECCCCEEEECCCCCEEEEECCCHHH
KKAAETMKITAPDLKELGIIDQVISEPRGGAHRDVDSQAELIDNIIKQSLVELMLLSSEE
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
LVDKRWEKYKQMGTFMS
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPILDFEKPIVNLKEKIVELKSFTENSEIDLTKEIETLEERLARLEEDIYGNLKPWNRV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QMARHPDRPTTMDYIERIFTDFIEFHGDRFYGEDEAIISGIGYYKDSPVTVIGHQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCH
KENIRRNFGMPHPEGYRKALRHMQQAEKFNRPIITFIDTKGAYPGKAAEERGQSEAIAKN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LMEMAGLQVPIICIVIGEGGSGGALGLGVGNHIHMLENSTYSVISPEGAAAILWKDSTQA
HHHHCCCCEEEEEEEEECCCCCCEEEECCCCEEEEECCCCEEEECCCCCEEEEECCCHHH
KKAAETMKITAPDLKELGIIDQVISEPRGGAHRDVDSQAELIDNIIKQSLVELMLLSSEE
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
LVDKRWEKYKQMGTFMS
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376