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The map label for this gene is minD [H]

Identifier: 23099504

GI number: 23099504

Start: 2075513

End: 2076307

Strand: Reverse

Name: minD [H]

Synonym: OB2049

Alternate gene names: 23099504

Gene position: 2076307-2075513 (Counterclockwise)

Preceding gene: 23099505

Following gene: 23099503

Centisome position: 57.19

GC content: 33.58

Gene sequence:

>795_bases
ATGGGTGAAGCTATCGTAATTACTTCTGGTAAAGGCGGAGTAGGAAAAACCACTACTTCAGCGAATATCGGAACTGCCCT
AGCATTAATGGAGAAAAAAGTATGTTTGATTGATACAGATATTGGACTTAGAAATTTAGATGTTGTAATGGGGTTAGAAA
ACAGAATAATTTTTGATATTGTTGATGTAATAGAGGAAAGATGTAAATTAAAACAAGCTCTTATAAAAGACAAACGTTTT
GATTATTTAACGCTATTACCTGCAGCGCAGACAAGTGATAAAACTGCTGTTACGATTCAAGGAATGAAAGAAATAATTGC
GGAATTAAAACAAGAGTATGATTATATTATAATTGATTGTCCAGCAGGAATAGAGCAAGGATTCCAAAATGCGATTGCAG
GTGCAGACCGAGCGATCGTAGTAACTACTCCGGAAAAATCCAGTGTGCGTGATGCAGATCGAATTGTAGGTTTATTAGAA
AAACAGGATATGAAAGAATCACCTAGATTGGTTATTAATCGTATACGTAATCATATGATGAAAAATGGTGACATGTTAGA
TATAGATGATATCGTTAATTTACTATCTATTGATTTAATTGGGATCGTTGTAGATGATGATGAAGTAATTAAAGCATCTA
ATAATGGAGAGCCAATTGCACTTCATCCAAATTCTAAGGCTTCGATTGCTTATCGAAATATTGCGAGAAGAATATTAGGG
GAGACAGTACCTTTGCAAGCACTTGATGATGAAAAAGGTATTTTCCAACGAGTAAAAGAATTTTTTAAAATATAA

Upstream 100 bases:

>100_bases
GGTATTATTGATACAGATCAAGATAAAATCACTATCGATTCCTTAAAGGTTCTTTCAAAAAAACGGAAAGAAATAAGTGG
ATTTGAGAGGAGAATGAATA

Downstream 100 bases:

>100_bases
TTCAACGTAAACACCTCAAAACAGTTGGTAGGTTTTGAGGTGTTTTTACATATAAATAATATTCCTTGTTCATAGAATGT
GAAGCTTGTACATATACATG

Product: septum site-determining protein

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGEAIVITSGKGGVGKTTTSANIGTALALMEKKVCLIDTDIGLRNLDVVMGLENRIIFDIVDVIEERCKLKQALIKDKRF
DYLTLLPAAQTSDKTAVTIQGMKEIIAELKQEYDYIIIDCPAGIEQGFQNAIAGADRAIVVTTPEKSSVRDADRIVGLLE
KQDMKESPRLVINRIRNHMMKNGDMLDIDDIVNLLSIDLIGIVVDDDEVIKASNNGEPIALHPNSKASIAYRNIARRILG
ETVPLQALDDEKGIFQRVKEFFKI

Sequences:

>Translated_264_residues
MGEAIVITSGKGGVGKTTTSANIGTALALMEKKVCLIDTDIGLRNLDVVMGLENRIIFDIVDVIEERCKLKQALIKDKRF
DYLTLLPAAQTSDKTAVTIQGMKEIIAELKQEYDYIIIDCPAGIEQGFQNAIAGADRAIVVTTPEKSSVRDADRIVGLLE
KQDMKESPRLVINRIRNHMMKNGDMLDIDDIVNLLSIDLIGIVVDDDEVIKASNNGEPIALHPNSKASIAYRNIARRILG
ETVPLQALDDEKGIFQRVKEFFKI
>Mature_263_residues
GEAIVITSGKGGVGKTTTSANIGTALALMEKKVCLIDTDIGLRNLDVVMGLENRIIFDIVDVIEERCKLKQALIKDKRFD
YLTLLPAAQTSDKTAVTIQGMKEIIAELKQEYDYIIIDCPAGIEQGFQNAIAGADRAIVVTTPEKSSVRDADRIVGLLEK
QDMKESPRLVINRIRNHMMKNGDMLDIDDIVNLLSIDLIGIVVDDDEVIKASNNGEPIALHPNSKASIAYRNIARRILGE
TVPLQALDDEKGIFQRVKEFFKI

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=267, Percent_Identity=46.0674157303371, Blast_Score=230, Evalue=7e-62,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29135; Mature: 29004

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAIVITSGKGGVGKTTTSANIGTALALMEKKVCLIDTDIGLRNLDVVMGLENRIIFDI
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCEEECCCCHHHHHH
VDVIEERCKLKQALIKDKRFDYLTLLPAAQTSDKTAVTIQGMKEIIAELKQEYDYIIIDC
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFQNAIAGADRAIVVTTPEKSSVRDADRIVGLLEKQDMKESPRLVINRIRNHMM
CCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KNGDMLDIDDIVNLLSIDLIGIVVDDDEVIKASNNGEPIALHPNSKASIAYRNIARRILG
CCCCEECHHHHHHHHHHEEEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHHC
ETVPLQALDDEKGIFQRVKEFFKI
CCCCCEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEAIVITSGKGGVGKTTTSANIGTALALMEKKVCLIDTDIGLRNLDVVMGLENRIIFDI
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCEEECCCCHHHHHH
VDVIEERCKLKQALIKDKRFDYLTLLPAAQTSDKTAVTIQGMKEIIAELKQEYDYIIIDC
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCEEEEEC
PAGIEQGFQNAIAGADRAIVVTTPEKSSVRDADRIVGLLEKQDMKESPRLVINRIRNHMM
CCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KNGDMLDIDDIVNLLSIDLIGIVVDDDEVIKASNNGEPIALHPNSKASIAYRNIARRILG
CCCCEECHHHHHHHHHHEEEEEEECCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHHC
ETVPLQALDDEKGIFQRVKEFFKI
CCCCCEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]