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The map label for this gene is minC

Identifier: 23099505

GI number: 23099505

Start: 2076300

End: 2076986

Strand: Reverse

Name: minC

Synonym: OB2050

Alternate gene names: 23099505

Gene position: 2076986-2076300 (Counterclockwise)

Preceding gene: 23099506

Following gene: 23099504

Centisome position: 57.21

GC content: 34.5

Gene sequence:

>687_bases
GTGCAGGATCTAAAACAAATCATTACAATTAAAGGTACCAGAGATGGATTAAGTCTATTTATTGATGAAGATGCATCATT
TGAAGAGGTTCTAAAAGAATTAGAAGAGAAAATTCAATTTAGTAAACCAAAACAAGATGAGCCTGTTGTGTCTGTTAAAG
TTAAATTAGGAAATCGATATATAAGTGGAGAAAAAGAAGAGCAGATTCGTCAAGTTATAACAACTGATCAGCGATTTAAA
GTGATCGGGATTGATTCAAATCTGATTCCGATTAACGATGCAAAGCGGTGGATGGACGATAGTGAAGTAAAAGTGATTAA
CCGTGTAGTTCGATCAGGTCAAATTCTAGAAATACAAGGAGATTTATTATTGGTTGGTGATGTAAATCCTGGGGGAAGAG
TGGTAGCTAGTGGGAATATCTATATATTAGGTAATCTATTAGGAATTGCTCATGCAGGTTATCATGGGGATAAAGATGCT
TTTATAGCAGCTTCTTATATGAAGCCAACACAATTACGAATTGCCGACTATATAAGTCGAGCACCTGACTATGAATCTGA
TGGTGTTTATATGGAATGTGGTATTATTGATACAGATCAAGATAAAATCACTATCGATTCCTTAAAGGTTCTTTCAAAAA
AACGGAAAGAAATAAGTGGATTTGAGAGGAGAATGAATAATGGGTGA

Upstream 100 bases:

>100_bases
GGAAAAATGGAAAACAGAAATTCCGCTTGGTGAACGAATGCGCTAAATAATATAAGATACATAGATCATTAATGTAGTGT
GAAAATGAGGTGATTAAAGA

Downstream 100 bases:

>100_bases
AGCTATCGTAATTACTTCTGGTAAAGGCGGAGTAGGAAAAACCACTACTTCAGCGAATATCGGAACTGCCCTAGCATTAA
TGGAGAAAAAAGTATGTTTG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MQDLKQIITIKGTRDGLSLFIDEDASFEEVLKELEEKIQFSKPKQDEPVVSVKVKLGNRYISGEKEEQIRQVITTDQRFK
VIGIDSNLIPINDAKRWMDDSEVKVINRVVRSGQILEIQGDLLLVGDVNPGGRVVASGNIYILGNLLGIAHAGYHGDKDA
FIAASYMKPTQLRIADYISRAPDYESDGVYMECGIIDTDQDKITIDSLKVLSKKRKEISGFERRMNNG

Sequences:

>Translated_228_residues
MQDLKQIITIKGTRDGLSLFIDEDASFEEVLKELEEKIQFSKPKQDEPVVSVKVKLGNRYISGEKEEQIRQVITTDQRFK
VIGIDSNLIPINDAKRWMDDSEVKVINRVVRSGQILEIQGDLLLVGDVNPGGRVVASGNIYILGNLLGIAHAGYHGDKDA
FIAASYMKPTQLRIADYISRAPDYESDGVYMECGIIDTDQDKITIDSLKVLSKKRKEISGFERRMNNG
>Mature_228_residues
MQDLKQIITIKGTRDGLSLFIDEDASFEEVLKELEEKIQFSKPKQDEPVVSVKVKLGNRYISGEKEEQIRQVITTDQRFK
VIGIDSNLIPINDAKRWMDDSEVKVINRVVRSGQILEIQGDLLLVGDVNPGGRVVASGNIYILGNLLGIAHAGYHGDKDA
FIAASYMKPTQLRIADYISRAPDYESDGVYMECGIIDTDQDKITIDSLKVLSKKRKEISGFERRMNNG

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_OCEIH (Q8EPP3)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692971.1
- ProteinModelPortal:   Q8EPP3
- SMR:   Q8EPP3
- GeneID:   1017827
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2050
- NMPDR:   fig|221109.1.peg.2048
- HOGENOM:   HBG399077
- OMA:   QQYVTIK
- ProtClustDB:   PRK00513
- BioCyc:   OIHE221109:OB2050-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 25591; Mature: 25591

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLKQIITIKGTRDGLSLFIDEDASFEEVLKELEEKIQFSKPKQDEPVVSVKVKLGNRY
CCCHHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEE
ISGEKEEQIRQVITTDQRFKVIGIDSNLIPINDAKRWMDDSEVKVINRVVRSGQILEIQG
ECCCHHHHHHHHHCCCCCEEEEECCCCEEECCCHHHHCCCCHHHHHHHHHHCCCEEEEEC
DLLLVGDVNPGGRVVASGNIYILGNLLGIAHAGYHGDKDAFIAASYMKPTQLRIADYISR
CEEEEEECCCCCEEEECCCEEEEEEHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
APDYESDGVYMECGIIDTDQDKITIDSLKVLSKKRKEISGFERRMNNG
CCCCCCCCEEEEECEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDLKQIITIKGTRDGLSLFIDEDASFEEVLKELEEKIQFSKPKQDEPVVSVKVKLGNRY
CCCHHHHEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEE
ISGEKEEQIRQVITTDQRFKVIGIDSNLIPINDAKRWMDDSEVKVINRVVRSGQILEIQG
ECCCHHHHHHHHHCCCCCEEEEECCCCEEECCCHHHHCCCCHHHHHHHHHHCCCEEEEEC
DLLLVGDVNPGGRVVASGNIYILGNLLGIAHAGYHGDKDAFIAASYMKPTQLRIADYISR
CEEEEEECCCCCEEEECCCEEEEEEHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHH
APDYESDGVYMECGIIDTDQDKITIDSLKVLSKKRKEISGFERRMNNG
CCCCCCCCEEEEECEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376