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The map label for this gene is pheA [H]

Identifier: 23099496

GI number: 23099496

Start: 2069560

End: 2070414

Strand: Reverse

Name: pheA [H]

Synonym: OB2041

Alternate gene names: 23099496

Gene position: 2070414-2069560 (Counterclockwise)

Preceding gene: 23099497

Following gene: 23099495

Centisome position: 57.03

GC content: 36.37

Gene sequence:

>855_bases
GTGACAAGTATAGGGTATTTAGGACCAAAAGGAACATTTACTAAAATGGCAGTAGATTCAGTCTTTAATGGAGAAATGAA
AAATGGATATAGAACCATTCCAGAATGTATCGATGCAGTCGATAAAGGTGAAGTAGATATTGGAGTTGTGCCAATAGAAA
ATGCAATAGAAGGTACGGTTCAATTGACAATTGATTATTTAATACATCAAGTGCGATTGCCGGTTGTTGGTGAAATAGTA
GTACCAATCCAACAACATTTACTTGTGCGAAAAGAAGTAACAAACAACCTGTCAGATATTCAAGAAGTATATTCGCATAG
TCATGCTATTGCACAATGTCACCAATATCTACACCGTCACTTGCATGCTGCAACGACAAAACATACGTCGTCAACCGGAA
AAGCTGCTGAAATCGTAAGTAACTCAAATGAGCCCATCGCTGCAATTGGAAATCGGTTAGCGGCAGAAGAATATGGGTTA
CATATTTTCCAAGAAAATATTCATGATTATCCCAATAATCATACACGATTTTTAGTTTTATCGAATCATCCGGAGAAGGT
ACACATTAAGCATAAAAAAGATTCCGAAAAAACGACGATGCTGATTACTTTACCAAATGATCAGTCTGGTGCGCTTCATC
AGATTTTATCTGCTTTTTCATGGAGAAAATTAAATTTGTCTAAAATTGAATCACGACCGACGAAAACGGGATTAGGTAAT
TATTTCTTTATTATTGATGTAGATCAACCCTATGATGATGTGTTATTTCCTGGTGTGAAATCAGAGCTGGAAGCACTTGG
CTGTCAAGTGACGATCTTAGGTACTTACCCTGTATACCATATGTTACAAAACTAA

Upstream 100 bases:

>100_bases
AAAAAGGAGCCCAAGACGGGGATGTTGTCAGATTGCTTGAGTATGAATTTGAATTTATAGAGTAACTATGATGCAACAGT
AGCTGCAAGGGGGAAGTAAA

Downstream 100 bases:

>100_bases
ACCTAAAGTAATTAATGATGTGAGCTATCGATATAAAATCGATAGCTTTTTTATTTTTAATAGGAGTTTATAGATATATC
TATAGTGGATGATTTAACTA

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTSIGYLGPKGTFTKMAVDSVFNGEMKNGYRTIPECIDAVDKGEVDIGVVPIENAIEGTVQLTIDYLIHQVRLPVVGEIV
VPIQQHLLVRKEVTNNLSDIQEVYSHSHAIAQCHQYLHRHLHAATTKHTSSTGKAAEIVSNSNEPIAAIGNRLAAEEYGL
HIFQENIHDYPNNHTRFLVLSNHPEKVHIKHKKDSEKTTMLITLPNDQSGALHQILSAFSWRKLNLSKIESRPTKTGLGN
YFFIIDVDQPYDDVLFPGVKSELEALGCQVTILGTYPVYHMLQN

Sequences:

>Translated_284_residues
MTSIGYLGPKGTFTKMAVDSVFNGEMKNGYRTIPECIDAVDKGEVDIGVVPIENAIEGTVQLTIDYLIHQVRLPVVGEIV
VPIQQHLLVRKEVTNNLSDIQEVYSHSHAIAQCHQYLHRHLHAATTKHTSSTGKAAEIVSNSNEPIAAIGNRLAAEEYGL
HIFQENIHDYPNNHTRFLVLSNHPEKVHIKHKKDSEKTTMLITLPNDQSGALHQILSAFSWRKLNLSKIESRPTKTGLGN
YFFIIDVDQPYDDVLFPGVKSELEALGCQVTILGTYPVYHMLQN
>Mature_283_residues
TSIGYLGPKGTFTKMAVDSVFNGEMKNGYRTIPECIDAVDKGEVDIGVVPIENAIEGTVQLTIDYLIHQVRLPVVGEIVV
PIQQHLLVRKEVTNNLSDIQEVYSHSHAIAQCHQYLHRHLHAATTKHTSSTGKAAEIVSNSNEPIAAIGNRLAAEEYGLH
IFQENIHDYPNNHTRFLVLSNHPEKVHIKHKKDSEKTTMLITLPNDQSGALHQILSAFSWRKLNLSKIESRPTKTGLGNY
FFIIDVDQPYDDVLFPGVKSELEALGCQVTILGTYPVYHMLQN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=279, Percent_Identity=29.3906810035842, Blast_Score=120, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6324013, Length=269, Percent_Identity=26.0223048327138, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31739; Mature: 31607

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIGYLGPKGTFTKMAVDSVFNGEMKNGYRTIPECIDAVDKGEVDIGVVPIENAIEGTV
CCCCCCCCCCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCCEEEEEEECCCHHCCHH
QLTIDYLIHQVRLPVVGEIVVPIQQHLLVRKEVTNNLSDIQEVYSHSHAIAQCHQYLHRH
EEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LHAATTKHTSSTGKAAEIVSNSNEPIAAIGNRLAAEEYGLHIFQENIHDYPNNHTRFLVL
HHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SNHPEKVHIKHKKDSEKTTMLITLPNDQSGALHQILSAFSWRKLNLSKIESRPTKTGLGN
ECCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC
YFFIIDVDQPYDDVLFPGVKSELEALGCQVTILGTYPVYHMLQN
EEEEEECCCCCCHHCCCCHHHHHHHCCCEEEEEECCHHHHHHCC
>Mature Secondary Structure 
TSIGYLGPKGTFTKMAVDSVFNGEMKNGYRTIPECIDAVDKGEVDIGVVPIENAIEGTV
CCCCCCCCCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCCEEEEEEECCCHHCCHH
QLTIDYLIHQVRLPVVGEIVVPIQQHLLVRKEVTNNLSDIQEVYSHSHAIAQCHQYLHRH
EEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LHAATTKHTSSTGKAAEIVSNSNEPIAAIGNRLAAEEYGLHIFQENIHDYPNNHTRFLVL
HHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
SNHPEKVHIKHKKDSEKTTMLITLPNDQSGALHQILSAFSWRKLNLSKIESRPTKTGLGN
ECCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCC
YFFIIDVDQPYDDVLFPGVKSELEALGCQVTILGTYPVYHMLQN
EEEEEECCCCCCHHCCCCHHHHHHHCCCEEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]