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The map label for this gene is ftsA [H]

Identifier: 23098927

GI number: 23098927

Start: 1512422

End: 1513708

Strand: Direct

Name: ftsA [H]

Synonym: OB1472

Alternate gene names: 23098927

Gene position: 1512422-1513708 (Clockwise)

Preceding gene: 23098926

Following gene: 23098928

Centisome position: 41.66

GC content: 37.06

Gene sequence:

>1287_bases
TTGGATAATAGTGAAGTTTTAGTAAGCCTAGATATTGGAACGACAATGATTAAAGTGATTATAGGAGAAGTACAATCAGA
TTCTCTAAATATTATTGGAGTAGGTACTGCAAAATCAAATGGCATGAAAAAGGGTGCAATTGTTGATATCGATCAGACGG
TACATTCTATTCGAAATGCTGTAGAACAAGCAGAACGTATGGTTGGAATGCATATTGAACGAGTGGTTGTAGGCATTAAT
GGCAGTCACATACAATTACAGCCTTGTCATGGTGTAGTTGCAGTACAGAGTGAGAATCGTGAAATTGGAGATGAAGATGT
CACGAGAGTCATTGATGGTGCTCAAGTTATATCTATACCACCAGAACGCGAAATCATAGATGTTATACCTCGACAATTTA
TTGTAGACGGTTTGGATGAAATAACAGATCCAAGAGGTATGATTGGTGTCCGCCTTGAAATGGAAGGAACGATTATTACT
TGTTCGAAGACAGTTCTACATAATATATTAAAATGTGTGGAGCGTGCTAATTTAGAGGTATCTGATATTTGTCTTCAGCC
TCTTGCTGCTGGTACAATAGCATTGTCAAAAGATGAAATGAATATGGGAGCAGCTTTAATTGATATAGGTGGAGGATGTA
CGACTGTATCTGTCTTTGAAAATGATCATCTAGTTGCAACAAGTGTAATTAGCCTTGGTGGAGATAATATTACCAAAGAC
CTTTCGATTGGTCTGCGAACTTCCACGGAAGAAGCGGAAGATATTAAGATGAATTATGGCCATGCTTTTTATGATGATGC
TCAAGAAGATGAGACATTTGAAGTTTCAACAATTGGAAGTAACCAGAGACAAGTTTTTAATCAGTTACAAATTGCAGATA
TGATTGAAGCTAGATTAGAAGAAATTTATGCTTATGTAGAAAGAGAAATTCGTAAAATGGGTTATAGGGAACTTCCAGGA
GGGTATGTATTAACCGGTGGTACCATTGCAATGCCTGGAAGTCTAGAGTTAGCGCAGGATTTATTTTACTCGAATGTACG
AGTTGCGATCCCTGATTATATTGGGGTGAGAGAGCCACAATTCACCTCGGGAATTGGAATTCTGCAATTTGCTTATCGTA
ATGCGAAGATACAAGGGAAAGAGTTGTACCCATCCGTTATCTTGGATGCGGCTAGCCCACAAAAACCTAAAAAACAAATA
AAACCATCTAAAGAGAAAAAGGAAAAAAACGAAAGTAAAAAGAAAGAATCAGGTTTTGCGAATCTATTTAAATATTTCTT
TGACTAA

Upstream 100 bases:

>100_bases
TATTTTTTCATTGAAATATTTTAAAATAGTAGACTCTACAATGAATGGATAACGTAGTTTTAAGAAACATAGGAAATGTT
TCTGTAGGAGGTGCCTTTAA

Downstream 100 bases:

>100_bases
ACTAATAGATTTTTAAAGTTATAATTAATTTCGTTAAACATGTAATCTGGATATTAGGAGGAACGGACTATGTTGGATTT
TGATACAAATATGGAAGAAC

Product: cell-division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDNSEVLVSLDIGTTMIKVIIGEVQSDSLNIIGVGTAKSNGMKKGAIVDIDQTVHSIRNAVEQAERMVGMHIERVVVGIN
GSHIQLQPCHGVVAVQSENREIGDEDVTRVIDGAQVISIPPEREIIDVIPRQFIVDGLDEITDPRGMIGVRLEMEGTIIT
CSKTVLHNILKCVERANLEVSDICLQPLAAGTIALSKDEMNMGAALIDIGGGCTTVSVFENDHLVATSVISLGGDNITKD
LSIGLRTSTEEAEDIKMNYGHAFYDDAQEDETFEVSTIGSNQRQVFNQLQIADMIEARLEEIYAYVEREIRKMGYRELPG
GYVLTGGTIAMPGSLELAQDLFYSNVRVAIPDYIGVREPQFTSGIGILQFAYRNAKIQGKELYPSVILDAASPQKPKKQI
KPSKEKKEKNESKKKESGFANLFKYFFD

Sequences:

>Translated_428_residues
MDNSEVLVSLDIGTTMIKVIIGEVQSDSLNIIGVGTAKSNGMKKGAIVDIDQTVHSIRNAVEQAERMVGMHIERVVVGIN
GSHIQLQPCHGVVAVQSENREIGDEDVTRVIDGAQVISIPPEREIIDVIPRQFIVDGLDEITDPRGMIGVRLEMEGTIIT
CSKTVLHNILKCVERANLEVSDICLQPLAAGTIALSKDEMNMGAALIDIGGGCTTVSVFENDHLVATSVISLGGDNITKD
LSIGLRTSTEEAEDIKMNYGHAFYDDAQEDETFEVSTIGSNQRQVFNQLQIADMIEARLEEIYAYVEREIRKMGYRELPG
GYVLTGGTIAMPGSLELAQDLFYSNVRVAIPDYIGVREPQFTSGIGILQFAYRNAKIQGKELYPSVILDAASPQKPKKQI
KPSKEKKEKNESKKKESGFANLFKYFFD
>Mature_428_residues
MDNSEVLVSLDIGTTMIKVIIGEVQSDSLNIIGVGTAKSNGMKKGAIVDIDQTVHSIRNAVEQAERMVGMHIERVVVGIN
GSHIQLQPCHGVVAVQSENREIGDEDVTRVIDGAQVISIPPEREIIDVIPRQFIVDGLDEITDPRGMIGVRLEMEGTIIT
CSKTVLHNILKCVERANLEVSDICLQPLAAGTIALSKDEMNMGAALIDIGGGCTTVSVFENDHLVATSVISLGGDNITKD
LSIGLRTSTEEAEDIKMNYGHAFYDDAQEDETFEVSTIGSNQRQVFNQLQIADMIEARLEEIYAYVEREIRKMGYRELPG
GYVLTGGTIAMPGSLELAQDLFYSNVRVAIPDYIGVREPQFTSGIGILQFAYRNAKIQGKELYPSVILDAASPQKPKKQI
KPSKEKKEKNESKKKESGFANLFKYFFD

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=384, Percent_Identity=32.5520833333333, Blast_Score=212, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46983; Mature: 46983

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNSEVLVSLDIGTTMIKVIIGEVQSDSLNIIGVGTAKSNGMKKGAIVDIDQTVHSIRNA
CCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
VEQAERMVGMHIERVVVGINGSHIQLQPCHGVVAVQSENREIGDEDVTRVIDGAQVISIP
HHHHHHHHHHEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEECC
PEREIIDVIPRQFIVDGLDEITDPRGMIGVRLEMEGTIITCSKTVLHNILKCVERANLEV
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHCCCCH
SDICLQPLAAGTIALSKDEMNMGAALIDIGGGCTTVSVFENDHLVATSVISLGGDNITKD
HHHHHHHHCCCEEEEECCCCCCCEEEEEECCCEEEEEEECCCCEEEEHHHHCCCCCCCCC
LSIGLRTSTEEAEDIKMNYGHAFYDDAQEDETFEVSTIGSNQRQVFNQLQIADMIEARLE
EEECEECCCCCHHHHEECCCCEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
EIYAYVEREIRKMGYRELPGGYVLTGGTIAMPGSLELAQDLFYSNVRVAIPDYIGVREPQ
HHHHHHHHHHHHCCCCCCCCCEEEECCEEECCCCHHHHHHHHHCCCEEECCCCCCCCCCC
FTSGIGILQFAYRNAKIQGKELYPSVILDAASPQKPKKQIKPSKEKKEKNESKKKESGFA
CCCCCHHEEEHHHCCCCCCHHCCCHHEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
NLFKYFFD
HHHHHHCC
>Mature Secondary Structure
MDNSEVLVSLDIGTTMIKVIIGEVQSDSLNIIGVGTAKSNGMKKGAIVDIDQTVHSIRNA
CCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
VEQAERMVGMHIERVVVGINGSHIQLQPCHGVVAVQSENREIGDEDVTRVIDGAQVISIP
HHHHHHHHHHEEEEEEEECCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHCCCEEEECC
PEREIIDVIPRQFIVDGLDEITDPRGMIGVRLEMEGTIITCSKTVLHNILKCVERANLEV
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEECHHHHHHHHHHHHHCCCCH
SDICLQPLAAGTIALSKDEMNMGAALIDIGGGCTTVSVFENDHLVATSVISLGGDNITKD
HHHHHHHHCCCEEEEECCCCCCCEEEEEECCCEEEEEEECCCCEEEEHHHHCCCCCCCCC
LSIGLRTSTEEAEDIKMNYGHAFYDDAQEDETFEVSTIGSNQRQVFNQLQIADMIEARLE
EEECEECCCCCHHHHEECCCCEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
EIYAYVEREIRKMGYRELPGGYVLTGGTIAMPGSLELAQDLFYSNVRVAIPDYIGVREPQ
HHHHHHHHHHHHCCCCCCCCCEEEECCEEECCCCHHHHHHHHHCCCEEECCCCCCCCCCC
FTSGIGILQFAYRNAKIQGKELYPSVILDAASPQKPKKQIKPSKEKKEKNESKKKESGFA
CCCCCHHEEEHHHCCCCCCHHCCCHHEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHH
NLFKYFFD
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3139638; 9384377; 1569582; 1624452 [H]