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The map label for this gene is ftsZ [H]

Identifier: 23098928

GI number: 23098928

Start: 1513778

End: 1514953

Strand: Direct

Name: ftsZ [H]

Synonym: OB1473

Alternate gene names: 23098928

Gene position: 1513778-1514953 (Clockwise)

Preceding gene: 23098927

Following gene: 23098929

Centisome position: 41.7

GC content: 39.46

Gene sequence:

>1176_bases
ATGTTGGATTTTGATACAAATATGGAAGAACTCGCAACAATTAAAGTTATAGGAGTAGGTGGAGGCGGTAATAACGCTGT
AAACCGAATGATAGAGCATGGTGTTGAAGGTGTAGAATTTATTGCTGTAAACACAGATGCACAAGCGTTAAACTTGTCAA
AAGCTGAATCCAAAATTCAAATCGGAGGTAAGCTAACTAGAGGGCTCGGTGCTGGAGCCAATCCTGAAGTTGGTAAAAAA
GCTGCCGAAGAAAGTAAAGAACAGTTGGAAGAAGTACTTAAAGGTGCGGATATGGTATTTGTTACTGCTGGAATGGGCGG
TGGAACTGGAACGGGAGCTGCCCCTGTTATTGCACAAGTAGCTAAAGACATTGGCGCTTTAACCGTAGGTGTTGTAACTC
GTCCATTTAGCTTCGAAGGAAGAAGACGCTCTACGCAAGCAGTCTCTGGTATTGATACGTTAAAAGGAGCTGTAGATACA
CTAATTGTCATTCCTAACGATCGATTACTTGAAATTGTTGACAAGAATACACCAATGCTTGAAGCATTCCGAGAAGCAGA
TAATGTACTTCGTCAAGGTGTACAAGGTATTTCTGATTTAATTGCAAAACCAGGTCTTATTAATGTTGACTTTGCTGATG
TGAAGACAATCATGTTTGATAAGGGTTCTGCATTAATGGGAATTGGTATTGCTACAGGAGAAACAAGAGCAACAGAAGCA
GCGAAAAAAGCTATTTCCTCTCCACTATTAGAAACATCTATAGATGGTGCGCATGGAATACTTATGAACATTACAGGTGG
AACAAACTTAAGTTTGTATGAAGTTCAAGAAGCTGCAGATCTTGTAACCTCTGCTGCTGATCAAGAAGTAAATGTTATCT
TTGGTTCAGTAATAAATGAAAACTTAAACGACGAGATTGTTGTCACTGTTATTGCTACTGGTTTTGATGAAAATGCTAAA
AAAGTAGATACTAGACAAAAACAACAACGAACGAACATTGGGCAGTCACAACAAACAGCTTCTAAAGATTTGAATGAAGC
TGCAAGTACGAGAGAAACTAGAGAATCAAGAGAATCACAACAACCTTCCCAGCCGCAGGCTCAATCTCGTCCACGTCAAG
ACGAGGAAGAATTGGACATTCCAACATTCTTAAGAAATCGTAATAGAAATCGATAG

Upstream 100 bases:

>100_bases
TGCGAATCTATTTAAATATTTCTTTGACTAAACTAATAGATTTTTAAAGTTATAATTAATTTCGTTAAACATGTAATCTG
GATATTAGGAGGAACGGACT

Downstream 100 bases:

>100_bases
GAAGTAAATAAACTCGCAAATATGCTAATAAAATCCAGCTATCCATAGATAGCTGGATTTTTTGTGCGAAATAAATTAAT
AACGGAGAAATTAATTTCAT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLDFDTNMEELATIKVIGVGGGGNNAVNRMIEHGVEGVEFIAVNTDAQALNLSKAESKIQIGGKLTRGLGAGANPEVGKK
AAEESKEQLEEVLKGADMVFVTAGMGGGTGTGAAPVIAQVAKDIGALTVGVVTRPFSFEGRRRSTQAVSGIDTLKGAVDT
LIVIPNDRLLEIVDKNTPMLEAFREADNVLRQGVQGISDLIAKPGLINVDFADVKTIMFDKGSALMGIGIATGETRATEA
AKKAISSPLLETSIDGAHGILMNITGGTNLSLYEVQEAADLVTSAADQEVNVIFGSVINENLNDEIVVTVIATGFDENAK
KVDTRQKQQRTNIGQSQQTASKDLNEAASTRETRESRESQQPSQPQAQSRPRQDEEELDIPTFLRNRNRNR

Sequences:

>Translated_391_residues
MLDFDTNMEELATIKVIGVGGGGNNAVNRMIEHGVEGVEFIAVNTDAQALNLSKAESKIQIGGKLTRGLGAGANPEVGKK
AAEESKEQLEEVLKGADMVFVTAGMGGGTGTGAAPVIAQVAKDIGALTVGVVTRPFSFEGRRRSTQAVSGIDTLKGAVDT
LIVIPNDRLLEIVDKNTPMLEAFREADNVLRQGVQGISDLIAKPGLINVDFADVKTIMFDKGSALMGIGIATGETRATEA
AKKAISSPLLETSIDGAHGILMNITGGTNLSLYEVQEAADLVTSAADQEVNVIFGSVINENLNDEIVVTVIATGFDENAK
KVDTRQKQQRTNIGQSQQTASKDLNEAASTRETRESRESQQPSQPQAQSRPRQDEEELDIPTFLRNRNRNR
>Mature_391_residues
MLDFDTNMEELATIKVIGVGGGGNNAVNRMIEHGVEGVEFIAVNTDAQALNLSKAESKIQIGGKLTRGLGAGANPEVGKK
AAEESKEQLEEVLKGADMVFVTAGMGGGTGTGAAPVIAQVAKDIGALTVGVVTRPFSFEGRRRSTQAVSGIDTLKGAVDT
LIVIPNDRLLEIVDKNTPMLEAFREADNVLRQGVQGISDLIAKPGLINVDFADVKTIMFDKGSALMGIGIATGETRATEA
AKKAISSPLLETSIDGAHGILMNITGGTNLSLYEVQEAADLVTSAADQEVNVIFGSVINENLNDEIVVTVIATGFDENAK
KVDTRQKQQRTNIGQSQQTASKDLNEAASTRETRESRESQQPSQPQAQSRPRQDEEELDIPTFLRNRNRNR

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=367, Percent_Identity=47.9564032697548, Blast_Score=298, Evalue=4e-82,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 41599; Mature: 41599

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFDTNMEELATIKVIGVGGGGNNAVNRMIEHGVEGVEFIAVNTDAQALNLSKAESKIQ
CCCCCCCHHHEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCHHHCHHHHHCCEE
IGGKLTRGLGAGANPEVGKKAAEESKEQLEEVLKGADMVFVTAGMGGGTGTGAAPVIAQV
ECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKDIGALTVGVVTRPFSFEGRRRSTQAVSGIDTLKGAVDTLIVIPNDRLLEIVDKNTPML
HHHHHHEEEHHEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCEEHHHCCCCHHH
EAFREADNVLRQGVQGISDLIAKPGLINVDFADVKTIMFDKGSALMGIGIATGETRATEA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHEEEECCCCEEEEEEEECCCHHHHHH
AKKAISSPLLETSIDGAHGILMNITGGTNLSLYEVQEAADLVTSAADQEVNVIFGSVINE
HHHHHHCCHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCC
NLNDEIVVTVIATGFDENAKKVDTRQKQQRTNIGQSQQTASKDLNEAASTRETRESRESQ
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
QPSQPQAQSRPRQDEEELDIPTFLRNRNRNR
CCCCCHHHCCCCCCHHHCCCHHHHHCCCCCC
>Mature Secondary Structure
MLDFDTNMEELATIKVIGVGGGGNNAVNRMIEHGVEGVEFIAVNTDAQALNLSKAESKIQ
CCCCCCCHHHEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCHHHCHHHHHCCEE
IGGKLTRGLGAGANPEVGKKAAEESKEQLEEVLKGADMVFVTAGMGGGTGTGAAPVIAQV
ECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
AKDIGALTVGVVTRPFSFEGRRRSTQAVSGIDTLKGAVDTLIVIPNDRLLEIVDKNTPML
HHHHHHEEEHHEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCEEHHHCCCCHHH
EAFREADNVLRQGVQGISDLIAKPGLINVDFADVKTIMFDKGSALMGIGIATGETRATEA
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHEEEECCCCEEEEEEEECCCHHHHHH
AKKAISSPLLETSIDGAHGILMNITGGTNLSLYEVQEAADLVTSAADQEVNVIFGSVINE
HHHHHHCCHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCC
NLNDEIVVTVIATGFDENAKKVDTRQKQQRTNIGQSQQTASKDLNEAASTRETRESRESQ
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
QPSQPQAQSRPRQDEEELDIPTFLRNRNRNR
CCCCCHHHCCCCCCHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3139638; 9384377; 2108961 [H]