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The map label for this gene is pycA [H]

Identifier: 23098885

GI number: 23098885

Start: 1469676

End: 1473119

Strand: Direct

Name: pycA [H]

Synonym: OB1430

Alternate gene names: 23098885

Gene position: 1469676-1473119 (Clockwise)

Preceding gene: 23098884

Following gene: 23098889

Centisome position: 40.48

GC content: 36.82

Gene sequence:

>3444_bases
ATGGCAGAGTTAAACAAGATTAACAAAGTACTAGTAGCAAACCGAGGGGAAATTGCAATTCGCGTCTTCCGAGCATGTAC
GGAGTTAAATATACGCACTGTTGCTATTTATTCCAAAGAGGATTCATCTGCTTTTCATCGATTCAAGGCAGATGAAGCTT
ATTTAATAGGTGAAGGGAAAAAACCGATTGATGCATACTTAGATATTGAAGGGATTATTGAACTTGCAAAAGAAGTCAAT
GTTGATGCAATTCACCCGGGTTATGGATTCCTTTCTGAAAATATACAGTTTGCAAGACGCTGTGAAGAAGAAGGAATTAT
CTTTATTGGACCAACTAGTAAACACTTAAGTATGTTTGGTGATAAGGTGAAAGCAAGAGAGCAAGCAGTAGCAGCTAACT
TACCAATCATACCTGGAAGTGATGGTCCAGTAAGCTCATTAGAAGAAGTTCAAGACTTTACTCAGGAACATGGATATCCA
ATAATTATTAAAGCTTCCTTAGGTGGCGGCGGTCGTGGAATGCGTGTAGTGAAAGATGATAGTGAACTAGAGAGTGCATA
TGATCGGGCGAAATCAGAAGCTAAAGCCGCTTTTGGGAACGATGAGATATATGTAGAGAGGTTAATCGAAAATCCTAAAC
ATATCGAGGTTCAAATATTAGGAGATAATGCAGGCAATATTGTTCATTTATATGAAAGAGATTGTTCTGTCCAACGTCGA
CATCAAAAACTTATTGAAATAGCACCAAGTTTATCATTGGGAGATAAATTACGAGAAGATATCTGTCAATCTGCGGTAAA
CTTAATGAAAAATGTAGATTATTTAAATGCCGGAACAGTTGAATTTCTTGTTACCGATGATGAGTTTTTCTTTATTGAGG
TTAACCCTCGTGTACAAGTAGAACACACTATTACAGAAATGATTACTGGTATTGATATCGTCCAGTCTCAAATTAAGATT
GCTGATGGAGCTCAATTACACGATGAAACAGTAGGAATTCCGACACAAGAACATATAAATACACAGGGCTATGCGATTCA
ATCAAGGGTAACAACGGAAGATCCACTTAATGATTTTATGCCAGATGCAGGTAAAATTAATGCTTATCGTACCGGCGGTG
GGTTTGGTGTCCGTCTAGATGCGGGTAACGGCTATCAAGGAGCAATCATTTCTCCTCACTATGATTCGTTATTAGTGAAA
GTATCTACGTGGGCATTAACTTTTGAACAAGCTGCAATAAAAATGGTCAGAAATTTAAAAGAATTCCGTATTAGAGGGAT
AAAAACAAATATTCCGTTCCTAGAGAATGTAATGGTTCATCAAAAATTCTTATCTGGTGAATATGATACAACGTTTATCG
ATAAAACACCGGAGCTATTCATATTCCCGATAAGAAAAGACCGTGGAACAAAAATGCTTACGTATATCGCAAATACTACT
TTAAACGGAGGGGAAGGCATCGCTAATATTGAGAAGCCTGACTTTAGACCGTTGGATATTCCTGCTACAAACCATATTGA
ATCAGTATCTACCGGAACAAAACAAATCTTGGATAAGTATGGTCCTGAAGGTGTAGCGAAATGGATGAAAGAACAGAAGG
AAGTATTATTAACAGACACAACTTTCAGAGATGCACACCAATCGTTATTTGCGACACGTGTTCGTACGAATGACTTGCTT
CATATTGCTGAACCAACGTCTAAACTGCTGCCAAATCTTTTCTCTGTAGAAATGTGGGGAGGAGCAACGTACGATGTAGC
TTATCGTTTTCTTAAGGAAGATCCTTGGACAAGATTGTTAAAATTACGTGAAGAAATGCCGAACGTACTATTCCAAATGT
TATTACGTGCGAGTAATGCTGTAGGGTATAAAAATTATCCTGATAATCTCATTGAAGAATTTGTAAAGAAAAGCAGTGAA
GCGGGTATTGATGTATTCCGTATATTCGACAGCTTGAACTGGGTAGAAGGAATGAAGTTGACAATCGATGCGGTACGCAA
TTCAAATAAAATTGCTGAAGCAGCTATTTGTTATACAGGTGATATATTAGACACAGGTAGAAGTAAGTATGATGTGTCTT
ACTATCAAATGATGGCAAAAGAATTAGAATCTGCAGGTGCACATATCTTAGGTATTAAAGATATGGCTGGTTTATTAAAG
CCAGAGGCCGCTTATCAATTAATTCATAAATTAAAAGAGACGATTGATATACCCATTCATTTACACACTCATGATACGAG
TGGAAATGGTGTGTTCACATATGCTCGTGCTATTGAAGCTGGCGTAGATGCAGTAGATGTTGCAGTTGGGTCAATGGCAG
GTATGACTTCTCAACCAAGTGCACAGTCGCTTTATCATGCATTAGAGGGAACTCCATTCCAGCCGGATATTAATATTGAA
AATTATGAACGTATCGGGCATTATTGGGAAGGGATTCGTGATTACTATCAAGAATTTGAAAGTGGTATGAACGCACCACA
TACCGAAATTTATCATCATGAAATGCCTGGAGGACAATATAGTAACCTTCAGCAACAAGCAAAAGCCGTAGGGTTAGGTC
ATCGTTGGAATGAAGTTAAGAAAATGTTCCGTACGGTAAACGATATGTTTGGTGATATTGTTAAAGTAACACCTTCATCA
AAAGTTATTGGTGATATGACACTATTTATGGTGCAAAACGATTTAACAGAAGAAGATATCTATGAAAAAGGTGAATCTAT
TGATTTTCCAGATTCAGTAATAGAATTTGCTCAAGGTTACATTGGACAGCCTTATCAAGGATTCCCAGAGAAACTTCAAA
AAATCATATTAAAAGATAAAAAACCGATAACTGTTCGTCCAGGTGAATTACTAGAACCAATTGACTTTAAGGTGATGAGA
GATGAGTTATATGATAAGTTAAATCGTCCGATCACTAGCTTCGATTTAATTTCTTATGCACTATATCCAAAAGTGTTTAT
GGATTACCAAGCATTTACAGAAACGTATGGCGATATTTCTGTCCTTGATACTCCAACCTTCTTCTATGGTATGAAATTAG
GAGAAGTAATAGAAGTTGAAATCGAAAAAGGGAAGACGCTTATTGTTAAATTGGTTTCTATATCAGAGCCAAAAGAAGAT
GGTACTCGCGTGGTTTACTTCGATTTAAATGGTCAATCAAGAGAAATTACAATCAAGGATGAAAGTATTGAATCCTTGGT
TGCTGTTAAACCGCAAGTTGACAAAAATAATAAAAACCACCTAGGAGCTACTATGCCTGGGACTGTTTTAGAAGTAAATT
GCAGTAAAGGTGATAAAGTGACAAAAGGTCAGCACTTGATGACAAATGAAGCGATGAAGATGGAAACTTCGGTTCAAGCA
CCATTTGATGGTGTTATAAAAGAGATTCATGTATCGAATGGCGATACAATAGCAGTTAATGATTTATTAATAGAATTTGA
ATAA

Upstream 100 bases:

>100_bases
CAAAACAAGTAAATCAACAAGAGCAGGATAGGGAAGAGTTAGCACCAAAGCCTGCAATGCAAAATCAAAACTCAACTAAT
ATGTATAGAGGTGGTAAAAG

Downstream 100 bases:

>100_bases
CAGGATTAAAAATGCAAGCACTCATTTAGTAGCATTGCATGTCTGTTTTTAAGGAGGGTGACATTGTCACCCTCCTTATT
TAAGTGTGCCCGGCATGGGT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1147; Mature: 1146

Protein sequence:

>1147_residues
MAELNKINKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSSAFHRFKADEAYLIGEGKKPIDAYLDIEGIIELAKEVN
VDAIHPGYGFLSENIQFARRCEEEGIIFIGPTSKHLSMFGDKVKAREQAVAANLPIIPGSDGPVSSLEEVQDFTQEHGYP
IIIKASLGGGGRGMRVVKDDSELESAYDRAKSEAKAAFGNDEIYVERLIENPKHIEVQILGDNAGNIVHLYERDCSVQRR
HQKLIEIAPSLSLGDKLREDICQSAVNLMKNVDYLNAGTVEFLVTDDEFFFIEVNPRVQVEHTITEMITGIDIVQSQIKI
ADGAQLHDETVGIPTQEHINTQGYAIQSRVTTEDPLNDFMPDAGKINAYRTGGGFGVRLDAGNGYQGAIISPHYDSLLVK
VSTWALTFEQAAIKMVRNLKEFRIRGIKTNIPFLENVMVHQKFLSGEYDTTFIDKTPELFIFPIRKDRGTKMLTYIANTT
LNGGEGIANIEKPDFRPLDIPATNHIESVSTGTKQILDKYGPEGVAKWMKEQKEVLLTDTTFRDAHQSLFATRVRTNDLL
HIAEPTSKLLPNLFSVEMWGGATYDVAYRFLKEDPWTRLLKLREEMPNVLFQMLLRASNAVGYKNYPDNLIEEFVKKSSE
AGIDVFRIFDSLNWVEGMKLTIDAVRNSNKIAEAAICYTGDILDTGRSKYDVSYYQMMAKELESAGAHILGIKDMAGLLK
PEAAYQLIHKLKETIDIPIHLHTHDTSGNGVFTYARAIEAGVDAVDVAVGSMAGMTSQPSAQSLYHALEGTPFQPDINIE
NYERIGHYWEGIRDYYQEFESGMNAPHTEIYHHEMPGGQYSNLQQQAKAVGLGHRWNEVKKMFRTVNDMFGDIVKVTPSS
KVIGDMTLFMVQNDLTEEDIYEKGESIDFPDSVIEFAQGYIGQPYQGFPEKLQKIILKDKKPITVRPGELLEPIDFKVMR
DELYDKLNRPITSFDLISYALYPKVFMDYQAFTETYGDISVLDTPTFFYGMKLGEVIEVEIEKGKTLIVKLVSISEPKED
GTRVVYFDLNGQSREITIKDESIESLVAVKPQVDKNNKNHLGATMPGTVLEVNCSKGDKVTKGQHLMTNEAMKMETSVQA
PFDGVIKEIHVSNGDTIAVNDLLIEFE

Sequences:

>Translated_1147_residues
MAELNKINKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSSAFHRFKADEAYLIGEGKKPIDAYLDIEGIIELAKEVN
VDAIHPGYGFLSENIQFARRCEEEGIIFIGPTSKHLSMFGDKVKAREQAVAANLPIIPGSDGPVSSLEEVQDFTQEHGYP
IIIKASLGGGGRGMRVVKDDSELESAYDRAKSEAKAAFGNDEIYVERLIENPKHIEVQILGDNAGNIVHLYERDCSVQRR
HQKLIEIAPSLSLGDKLREDICQSAVNLMKNVDYLNAGTVEFLVTDDEFFFIEVNPRVQVEHTITEMITGIDIVQSQIKI
ADGAQLHDETVGIPTQEHINTQGYAIQSRVTTEDPLNDFMPDAGKINAYRTGGGFGVRLDAGNGYQGAIISPHYDSLLVK
VSTWALTFEQAAIKMVRNLKEFRIRGIKTNIPFLENVMVHQKFLSGEYDTTFIDKTPELFIFPIRKDRGTKMLTYIANTT
LNGGEGIANIEKPDFRPLDIPATNHIESVSTGTKQILDKYGPEGVAKWMKEQKEVLLTDTTFRDAHQSLFATRVRTNDLL
HIAEPTSKLLPNLFSVEMWGGATYDVAYRFLKEDPWTRLLKLREEMPNVLFQMLLRASNAVGYKNYPDNLIEEFVKKSSE
AGIDVFRIFDSLNWVEGMKLTIDAVRNSNKIAEAAICYTGDILDTGRSKYDVSYYQMMAKELESAGAHILGIKDMAGLLK
PEAAYQLIHKLKETIDIPIHLHTHDTSGNGVFTYARAIEAGVDAVDVAVGSMAGMTSQPSAQSLYHALEGTPFQPDINIE
NYERIGHYWEGIRDYYQEFESGMNAPHTEIYHHEMPGGQYSNLQQQAKAVGLGHRWNEVKKMFRTVNDMFGDIVKVTPSS
KVIGDMTLFMVQNDLTEEDIYEKGESIDFPDSVIEFAQGYIGQPYQGFPEKLQKIILKDKKPITVRPGELLEPIDFKVMR
DELYDKLNRPITSFDLISYALYPKVFMDYQAFTETYGDISVLDTPTFFYGMKLGEVIEVEIEKGKTLIVKLVSISEPKED
GTRVVYFDLNGQSREITIKDESIESLVAVKPQVDKNNKNHLGATMPGTVLEVNCSKGDKVTKGQHLMTNEAMKMETSVQA
PFDGVIKEIHVSNGDTIAVNDLLIEFE
>Mature_1146_residues
AELNKINKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSSAFHRFKADEAYLIGEGKKPIDAYLDIEGIIELAKEVNV
DAIHPGYGFLSENIQFARRCEEEGIIFIGPTSKHLSMFGDKVKAREQAVAANLPIIPGSDGPVSSLEEVQDFTQEHGYPI
IIKASLGGGGRGMRVVKDDSELESAYDRAKSEAKAAFGNDEIYVERLIENPKHIEVQILGDNAGNIVHLYERDCSVQRRH
QKLIEIAPSLSLGDKLREDICQSAVNLMKNVDYLNAGTVEFLVTDDEFFFIEVNPRVQVEHTITEMITGIDIVQSQIKIA
DGAQLHDETVGIPTQEHINTQGYAIQSRVTTEDPLNDFMPDAGKINAYRTGGGFGVRLDAGNGYQGAIISPHYDSLLVKV
STWALTFEQAAIKMVRNLKEFRIRGIKTNIPFLENVMVHQKFLSGEYDTTFIDKTPELFIFPIRKDRGTKMLTYIANTTL
NGGEGIANIEKPDFRPLDIPATNHIESVSTGTKQILDKYGPEGVAKWMKEQKEVLLTDTTFRDAHQSLFATRVRTNDLLH
IAEPTSKLLPNLFSVEMWGGATYDVAYRFLKEDPWTRLLKLREEMPNVLFQMLLRASNAVGYKNYPDNLIEEFVKKSSEA
GIDVFRIFDSLNWVEGMKLTIDAVRNSNKIAEAAICYTGDILDTGRSKYDVSYYQMMAKELESAGAHILGIKDMAGLLKP
EAAYQLIHKLKETIDIPIHLHTHDTSGNGVFTYARAIEAGVDAVDVAVGSMAGMTSQPSAQSLYHALEGTPFQPDINIEN
YERIGHYWEGIRDYYQEFESGMNAPHTEIYHHEMPGGQYSNLQQQAKAVGLGHRWNEVKKMFRTVNDMFGDIVKVTPSSK
VIGDMTLFMVQNDLTEEDIYEKGESIDFPDSVIEFAQGYIGQPYQGFPEKLQKIILKDKKPITVRPGELLEPIDFKVMRD
ELYDKLNRPITSFDLISYALYPKVFMDYQAFTETYGDISVLDTPTFFYGMKLGEVIEVEIEKGKTLIVKLVSISEPKEDG
TRVVYFDLNGQSREITIKDESIESLVAVKPQVDKNNKNHLGATMPGTVLEVNCSKGDKVTKGQHLMTNEAMKMETSVQAP
FDGVIKEIHVSNGDTIAVNDLLIEFE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=450, Percent_Identity=43.3333333333333, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI189095269, Length=461, Percent_Identity=42.0824295010846, Blast_Score=354, Evalue=3e-97,
Organism=Homo sapiens, GI65506442, Length=457, Percent_Identity=42.2319474835886, Blast_Score=353, Evalue=7e-97,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=42.2319474835886, Blast_Score=352, Evalue=1e-96,
Organism=Homo sapiens, GI38679971, Length=531, Percent_Identity=30.8851224105461, Blast_Score=237, Evalue=4e-62,
Organism=Homo sapiens, GI38679977, Length=531, Percent_Identity=30.8851224105461, Blast_Score=237, Evalue=5e-62,
Organism=Homo sapiens, GI38679967, Length=531, Percent_Identity=30.8851224105461, Blast_Score=237, Evalue=5e-62,
Organism=Homo sapiens, GI38679960, Length=531, Percent_Identity=30.8851224105461, Blast_Score=237, Evalue=5e-62,
Organism=Homo sapiens, GI38679974, Length=531, Percent_Identity=30.8851224105461, Blast_Score=237, Evalue=6e-62,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=30.5882352941176, Blast_Score=228, Evalue=2e-59,
Organism=Escherichia coli, GI1789654, Length=450, Percent_Identity=43.5555555555556, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17562816, Length=1147, Percent_Identity=48.9973844812555, Blast_Score=1130, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=459, Percent_Identity=42.483660130719, Blast_Score=346, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI71987519, Length=462, Percent_Identity=42.2077922077922, Blast_Score=338, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI133931226, Length=497, Percent_Identity=30.784708249497, Blast_Score=208, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71997168, Length=440, Percent_Identity=30, Blast_Score=201, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=30, Blast_Score=201, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1162, Percent_Identity=48.881239242685, Blast_Score=1114, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1162, Percent_Identity=49.0533562822719, Blast_Score=1098, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=37.3333333333333, Blast_Score=298, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6323863, Length=435, Percent_Identity=32.4137931034483, Blast_Score=213, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=28.7109375, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24652212, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1151, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1151, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1151, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1151, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1151, Percent_Identity=50.7384882710686, Blast_Score=1151, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1167, Percent_Identity=50.3856041131105, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1167, Percent_Identity=50.3856041131105, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1167, Percent_Identity=50.3856041131105, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1167, Percent_Identity=50.3856041131105, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1167, Percent_Identity=50.3856041131105, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=465, Percent_Identity=41.0752688172043, Blast_Score=357, Evalue=3e-98,
Organism=Drosophila melanogaster, GI24651759, Length=423, Percent_Identity=40.661938534279, Blast_Score=315, Evalue=1e-85,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=31.2127236580517, Blast_Score=234, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=31.2127236580517, Blast_Score=234, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=31.2127236580517, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=31.2127236580517, Blast_Score=233, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128660; Mature: 128529

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELNKINKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSSAFHRFKADEAYLIGEGK
CCCHHHCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHCCCCEEEEECCC
KPIDAYLDIEGIIELAKEVNVDAIHPGYGFLSENIQFARRCEEEGIIFIGPTSKHLSMFG
CCHHHHCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
DKVKAREQAVAANLPIIPGSDGPVSSLEEVQDFTQEHGYPIIIKASLGGGGRGMRVVKDD
HHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECC
SELESAYDRAKSEAKAAFGNDEIYVERLIENPKHIEVQILGDNAGNIVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHH
HQKLIEIAPSLSLGDKLREDICQSAVNLMKNVDYLNAGTVEFLVTDDEFFFIEVNPRVQV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECCCEEE
EHTITEMITGIDIVQSQIKIADGAQLHDETVGIPTQEHINTQGYAIQSRVTTEDPLNDFM
HHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHC
PDAGKINAYRTGGGFGVRLDAGNGYQGAIISPHYDSLLVKVSTWALTFEQAAIKMVRNLK
CCCCCEEEEEECCCEEEEEECCCCCCCCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
EFRIRGIKTNIPFLENVMVHQKFLSGEYDTTFIDKTPELFIFPIRKDRGTKMLTYIANTT
HHHHCCEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCEEEEEEECCC
LNGGEGIANIEKPDFRPLDIPATNHIESVSTGTKQILDKYGPEGVAKWMKEQKEVLLTDT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEECC
TFRDAHQSLFATRVRTNDLLHIAEPTSKLLPNLFSVEMWGGATYDVAYRFLKEDPWTRLL
HHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHH
KLREEMPNVLFQMLLRASNAVGYKNYPDNLIEEFVKKSSEAGIDVFRIFDSLNWVEGMKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHCCCEE
TIDAVRNSNKIAEAAICYTGDILDTGRSKYDVSYYQMMAKELESAGAHILGIKDMAGLLK
EEEECCCCCCHHHEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHCC
PEAAYQLIHKLKETIDIPIHLHTHDTSGNGVFTYARAIEAGVDAVDVAVGSMAGMTSQPS
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCCC
AQSLYHALEGTPFQPDINIENYERIGHYWEGIRDYYQEFESGMNAPHTEIYHHEMPGGQY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
SNLQQQAKAVGLGHRWNEVKKMFRTVNDMFGDIVKVTPSSKVIGDMTLFMVQNDLTEEDI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCEEEEEEECCCCHHHH
YEKGESIDFPDSVIEFAQGYIGQPYQGFPEKLQKIILKDKKPITVRPGELLEPIDFKVMR
HHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHH
DELYDKLNRPITSFDLISYALYPKVFMDYQAFTETYGDISVLDTPTFFYGMKLGEVIEVE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCEEEEE
IEKGKTLIVKLVSISEPKEDGTRVVYFDLNGQSREITIKDESIESLVAVKPQVDKNNKNH
ECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHEEECCCCCCCCCCC
LGATMPGTVLEVNCSKGDKVTKGQHLMTNEAMKMETSVQAPFDGVIKEIHVSNGDTIAVN
CCCCCCCCEEEEECCCCCCCCCCCHHHHCCHHHHHCCCCCCHHHHHHEEECCCCCEEEEE
DLLIEFE
EEEEEEC
>Mature Secondary Structure 
AELNKINKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSSAFHRFKADEAYLIGEGK
CCHHHCCEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHCCCCEEEEECCC
KPIDAYLDIEGIIELAKEVNVDAIHPGYGFLSENIQFARRCEEEGIIFIGPTSKHLSMFG
CCHHHHCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
DKVKAREQAVAANLPIIPGSDGPVSSLEEVQDFTQEHGYPIIIKASLGGGGRGMRVVKDD
HHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECC
SELESAYDRAKSEAKAAFGNDEIYVERLIENPKHIEVQILGDNAGNIVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHH
HQKLIEIAPSLSLGDKLREDICQSAVNLMKNVDYLNAGTVEFLVTDDEFFFIEVNPRVQV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEEECCCEEE
EHTITEMITGIDIVQSQIKIADGAQLHDETVGIPTQEHINTQGYAIQSRVTTEDPLNDFM
HHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCHHHHC
PDAGKINAYRTGGGFGVRLDAGNGYQGAIISPHYDSLLVKVSTWALTFEQAAIKMVRNLK
CCCCCEEEEEECCCEEEEEECCCCCCCCEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
EFRIRGIKTNIPFLENVMVHQKFLSGEYDTTFIDKTPELFIFPIRKDRGTKMLTYIANTT
HHHHCCEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCEEEEEEECCC
LNGGEGIANIEKPDFRPLDIPATNHIESVSTGTKQILDKYGPEGVAKWMKEQKEVLLTDT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHCCCEEEECC
TFRDAHQSLFATRVRTNDLLHIAEPTSKLLPNLFSVEMWGGATYDVAYRFLKEDPWTRLL
HHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHH
KLREEMPNVLFQMLLRASNAVGYKNYPDNLIEEFVKKSSEAGIDVFRIFDSLNWVEGMKL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHCCCEE
TIDAVRNSNKIAEAAICYTGDILDTGRSKYDVSYYQMMAKELESAGAHILGIKDMAGLLK
EEEECCCCCCHHHEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHCC
PEAAYQLIHKLKETIDIPIHLHTHDTSGNGVFTYARAIEAGVDAVDVAVGSMAGMTSQPS
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHHHHCCCHHHHHHHHHCCCCCCCC
AQSLYHALEGTPFQPDINIENYERIGHYWEGIRDYYQEFESGMNAPHTEIYHHEMPGGQY
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
SNLQQQAKAVGLGHRWNEVKKMFRTVNDMFGDIVKVTPSSKVIGDMTLFMVQNDLTEEDI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCEEEEEEECCCCHHHH
YEKGESIDFPDSVIEFAQGYIGQPYQGFPEKLQKIILKDKKPITVRPGELLEPIDFKVMR
HHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHH
DELYDKLNRPITSFDLISYALYPKVFMDYQAFTETYGDISVLDTPTFFYGMKLGEVIEVE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCEEEEE
IEKGKTLIVKLVSISEPKEDGTRVVYFDLNGQSREITIKDESIESLVAVKPQVDKNNKNH
ECCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHEEECCCCCCCCCCC
LGATMPGTVLEVNCSKGDKVTKGQHLMTNEAMKMETSVQAPFDGVIKEIHVSNGDTIAVN
CCCCCCCCEEEEECCCCCCCCCCCHHHHCCHHHHHCCCCCCHHHHHHEEECCCCCEEEEE
DLLIEFE
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]