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The map label for this gene is spxA

Identifier: 23098668

GI number: 23098668

Start: 1262572

End: 1262967

Strand: Direct

Name: spxA

Synonym: OB1213

Alternate gene names: 23098668

Gene position: 1262572-1262967 (Clockwise)

Preceding gene: 23098665

Following gene: 23098669

Centisome position: 34.78

GC content: 38.38

Gene sequence:

>396_bases
ATGGTAACACTTTATACCTCACCAAGCTGTACTTCCTGCAGGAAAGCAAGAGCGTGGCTGGAAGAACACAACATACCTTT
TACTGAGCGTAATATTTTTTCCGAGCCATTAAGTCTCGATGAAATAAAAGAAATATTGCGAATGACAGAGGATGGCACGG
ATGAGATTATTTCCACGAGATCAAAAGTATTCCAGAAGTTGGATGTAAATATTGATCAACTGCCAATGAAAAACTTATTC
AATCTAATCCAGAAAAATCCTGGGTTGTTGCGTAGGCCGATTATATTAGATGAGAAGCGTCTTCAAGTTGGTTATAATGA
AGATGAGATTCGTCGATTCTTACCAAGAACAGTTCGTACATTCCAATTGCGTGAAGCGCAACGTATGGTTAATTAA

Upstream 100 bases:

>100_bases
TGTAGTATAATAACTACATATGAGTTATTTAGACTAATTTTAATTTAATAAGTTAGTTAAAAAACTCGAAAATATATATT
AGATTGAGGAGTGAAGTTAC

Downstream 100 bases:

>100_bases
ATATAAAAGAAAAGAGTATCAAACCAAAGAAACGACATGGGAATCGTCCTGTGTCGTTTCTTTAATTTGGTGATTGGCGG
GCCTTAATATAAATAGGTGA

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MVTLYTSPSCTSCRKARAWLEEHNIPFTERNIFSEPLSLDEIKEILRMTEDGTDEIISTRSKVFQKLDVNIDQLPMKNLF
NLIQKNPGLLRRPIILDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRMVN

Sequences:

>Translated_131_residues
MVTLYTSPSCTSCRKARAWLEEHNIPFTERNIFSEPLSLDEIKEILRMTEDGTDEIISTRSKVFQKLDVNIDQLPMKNLF
NLIQKNPGLLRRPIILDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRMVN
>Mature_131_residues
MVTLYTSPSCTSCRKARAWLEEHNIPFTERNIFSEPLSLDEIKEILRMTEDGTDEIISTRSKVFQKLDVNIDQLPMKNLF
NLIQKNPGLLRRPIILDEKRLQVGYNEDEIRRFLPRTVRTFQLREAQRMVN

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX1_OCEIH (Q8ERT7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692134.1
- ProteinModelPortal:   Q8ERT7
- SMR:   Q8ERT7
- GeneID:   1017385
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1213
- NMPDR:   fig|221109.1.peg.1212
- HOGENOM:   HBG734370
- OMA:   FTERNIF
- ProtClustDB:   PRK01655
- BioCyc:   OIHE221109:OB1213-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 15523; Mature: 15523

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLYTSPSCTSCRKARAWLEEHNIPFTERNIFSEPLSLDEIKEILRMTEDGTDEIISTR
CEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDVNIDQLPMKNLFNLIQKNPGLLRRPIILDEKRLQVGYNEDEIRRFLPRTVRT
HHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHH
FQLREAQRMVN
HHHHHHHHHCC
>Mature Secondary Structure
MVTLYTSPSCTSCRKARAWLEEHNIPFTERNIFSEPLSLDEIKEILRMTEDGTDEIISTR
CEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDVNIDQLPMKNLFNLIQKNPGLLRRPIILDEKRLQVGYNEDEIRRFLPRTVRT
HHHHHHHCCCCHHCCHHHHHHHHHCCCCCCCCCEEECCHHHHCCCCHHHHHHHHHHHHHH
FQLREAQRMVN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376