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The map label for this gene is mecA [H]

Identifier: 23098669

GI number: 23098669

Start: 1263443

End: 1264144

Strand: Direct

Name: mecA [H]

Synonym: OB1214

Alternate gene names: 23098669

Gene position: 1263443-1264144 (Clockwise)

Preceding gene: 23098668

Following gene: 23098670

Centisome position: 34.8

GC content: 31.48

Gene sequence:

>702_bases
ATGGAGATAGAAAGAATAAATGAAAATACAATTAAGTTTTACATTTCTTATTTAGATATAGAAGAGCTTGGTTTTGAAAG
AGAAGAAATTTGGTACAATCGCGAAAGAAGTGAGCAACTTTTTTGGCAAATGATGGATGAAGTGAATTATCGAGAAGATT
TTAATCCAGAAGGACCTTTATGGATACAGGTTCAGGCAATGGAAAAAGGTTTAGAAATTATCGTTACGAAAGCAAAAGTG
TCTAAAAATGGTGAAAATCTAGAATTAGATACAGAAGATGGAAGTGTAGATATCCCTGTTGATGAAAAAATAGAAAGTAT
TCTCGGGGATAAATTCGGTAAGAACCTTAATGAATCTGAAGAATCTGATAGTGAAGACGACGAGTTAGAGGAAGATAACT
TATGGATTATTGTCGAGTTTGATGATTTTGAGGATTTAATTCAATTAAGTCATCAATTTGAAGATATATCTAACTTTGGA
GAAGAGACATTATATTTCTATAACAACCAATACTACTTGTATATGGAATTCTCGTATGATGTGTTAGATGATAATCGACA
AGAAGATGTAATTAGTCAGGTACTTGAGTATTCATCTGATTCATCTGTTTCCATTCATGTTTTAGAAGAATACGGAAAGA
AAGTAATGGAAAACGATACCTTCACCAATATTAGGAAACATTTTCCCTTACGCTTGAAATAA

Upstream 100 bases:

>100_bases
TGCATTATAAATAGTTTTGTGTAAATGAGTTTATACACGCTTGATGCACATGTGGGAAGGTAGCGGATAGCTTCTATAAT
CAAGAAGGGAGAGCGTGAAT

Downstream 100 bases:

>100_bases
ACAATCTCTTTAAAAGAGTTTGTTTATTTTTTTTGGAGGTTTTTTCTAAAACATGTCGAAATAAGTAATTAGGGAGGTGA
ATTAATGTAGTGCAAAAAGC

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MEIERINENTIKFYISYLDIEELGFEREEIWYNRERSEQLFWQMMDEVNYREDFNPEGPLWIQVQAMEKGLEIIVTKAKV
SKNGENLELDTEDGSVDIPVDEKIESILGDKFGKNLNESEESDSEDDELEEDNLWIIVEFDDFEDLIQLSHQFEDISNFG
EETLYFYNNQYYLYMEFSYDVLDDNRQEDVISQVLEYSSDSSVSIHVLEEYGKKVMENDTFTNIRKHFPLRLK

Sequences:

>Translated_233_residues
MEIERINENTIKFYISYLDIEELGFEREEIWYNRERSEQLFWQMMDEVNYREDFNPEGPLWIQVQAMEKGLEIIVTKAKV
SKNGENLELDTEDGSVDIPVDEKIESILGDKFGKNLNESEESDSEDDELEEDNLWIIVEFDDFEDLIQLSHQFEDISNFG
EETLYFYNNQYYLYMEFSYDVLDDNRQEDVISQVLEYSSDSSVSIHVLEEYGKKVMENDTFTNIRKHFPLRLK
>Mature_233_residues
MEIERINENTIKFYISYLDIEELGFEREEIWYNRERSEQLFWQMMDEVNYREDFNPEGPLWIQVQAMEKGLEIIVTKAKV
SKNGENLELDTEDGSVDIPVDEKIESILGDKFGKNLNESEESDSEDDELEEDNLWIIVEFDDFEDLIQLSHQFEDISNFG
EETLYFYNNQYYLYMEFSYDVLDDNRQEDVISQVLEYSSDSSVSIHVLEEYGKKVMENDTFTNIRKHFPLRLK

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 27871; Mature: 27871

Theoretical pI: Translated: 3.83; Mature: 3.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIERINENTIKFYISYLDIEELGFEREEIWYNRERSEQLFWQMMDEVNYREDFNPEGPL
CCCCCCCCCEEEEEEEEECHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCE
WIQVQAMEKGLEIIVTKAKVSKNGENLELDTEDGSVDIPVDEKIESILGDKFGKNLNESE
EEEEEEHHCCEEEEEEEEHHCCCCCCEEEECCCCCEECCHHHHHHHHHHHHHCCCCCCCC
ESDSEDDELEEDNLWIIVEFDDFEDLIQLSHQFEDISNFGEETLYFYNNQYYLYMEFSYD
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEEEE
VLDDNRQEDVISQVLEYSSDSSVSIHVLEEYGKKVMENDTFTNIRKHFPLRLK
ECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MEIERINENTIKFYISYLDIEELGFEREEIWYNRERSEQLFWQMMDEVNYREDFNPEGPL
CCCCCCCCCEEEEEEEEECHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCE
WIQVQAMEKGLEIIVTKAKVSKNGENLELDTEDGSVDIPVDEKIESILGDKFGKNLNESE
EEEEEEHHCCEEEEEEEEHHCCCCCCEEEECCCCCEECCHHHHHHHHHHHHHCCCCCCCC
ESDSEDDELEEDNLWIIVEFDDFEDLIQLSHQFEDISNFGEETLYFYNNQYYLYMEFSYD
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEEEEEE
VLDDNRQEDVISQVLEYSSDSSVSIHVLEEYGKKVMENDTFTNIRKHFPLRLK
ECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412687; 9384377 [H]