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The map label for this gene is fdhC [H]

Identifier: 23098225

GI number: 23098225

Start: 822986

End: 823840

Strand: Direct

Name: fdhC [H]

Synonym: OB0770

Alternate gene names: 23098225

Gene position: 822986-823840 (Clockwise)

Preceding gene: 23098223

Following gene: 23098226

Centisome position: 22.67

GC content: 35.2

Gene sequence:

>855_bases
ATGGATGATAATGGTAACAAAGAATCTACAAACCAAACAAAAGAAACGAAAGAAATCCCAGAAAGGCAATTTTTATTTCC
AGTCCAGGTAATGCAGTCCTTTAGTAATAAAGGAAAAGAACATCTTGATACAAATACTCCCTCACAGTTAGTGCTTGCAT
TAAAAGCAGGTTCATTTATGACCTTTGGCGCTGTCTTTTCTGTATTGTTAGCTATTGGTGTGGATGCAAAAGGACTAACA
TATATTTTACAGGGAATTGGCTTTACTGCAGGTTATCTAATGGTATTTATGTCACAATCCGTATTGTTTACGGAAGTTAA
TGTTCTTTTGCCAACATATTATTTACAAAAGTCTTACTGGATAAAGCATAAGTTTATCAAATTCTGGGCGGTCGCATATA
TTGGCAATCTTATAGGTGCGTTATTTGTGGCGTTATTAATTATTATCTCAAACTCTTTAACACCTGAATTCTCAAAAGAG
CTTGAAACACTAATCTCACATAAAATGAAATTTGCCGATTATGGATGGGCAGGCTGGTTCCAAGTACTGCTGTCAGGAAT
TTTAGCCAATTGGCTTATCGGTATGGCTACATTTCTAACAACATCTGCTAGGGACGTAGTAGGTAAGATATTAGGAACAG
CTCTTCCAGTTATTTTGTTTGTGGCAGGTAATTTTCAACATAGTGCAGCAAATATGGGATATTTCAGTTTAGGGATTTTA
ACATCTGATAACTATGCGTGGTATGAATATATATTGTTAAATTTAATCCCAGCTAGTATCGGAAATATTATTGGTGGAGC
TATATTCATCTCCTTGTTGTTCTTATATGCTTTTCGGAAAGAGATGCGAAGCTAA

Upstream 100 bases:

>100_bases
AAAGAATGAATGTATAATTATTCGGGTACATATATGGATAGGCTTTTAAGATATTAATTGTCCCAATTAACATAAAGTCA
ATGAAAATTGGAGGATATTT

Downstream 100 bases:

>100_bases
ACAAATTTATGGATCTCTCTAACCTGAAAAAGTGTGACGTTTATTGTCTCTCTTTTTTAGGCCTTTTACCTAAAATGTAC
AACTAAATAAATTATTACTA

Product: formate dehydrogenase

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MDDNGNKESTNQTKETKEIPERQFLFPVQVMQSFSNKGKEHLDTNTPSQLVLALKAGSFMTFGAVFSVLLAIGVDAKGLT
YILQGIGFTAGYLMVFMSQSVLFTEVNVLLPTYYLQKSYWIKHKFIKFWAVAYIGNLIGALFVALLIIISNSLTPEFSKE
LETLISHKMKFADYGWAGWFQVLLSGILANWLIGMATFLTTSARDVVGKILGTALPVILFVAGNFQHSAANMGYFSLGIL
TSDNYAWYEYILLNLIPASIGNIIGGAIFISLLFLYAFRKEMRS

Sequences:

>Translated_284_residues
MDDNGNKESTNQTKETKEIPERQFLFPVQVMQSFSNKGKEHLDTNTPSQLVLALKAGSFMTFGAVFSVLLAIGVDAKGLT
YILQGIGFTAGYLMVFMSQSVLFTEVNVLLPTYYLQKSYWIKHKFIKFWAVAYIGNLIGALFVALLIIISNSLTPEFSKE
LETLISHKMKFADYGWAGWFQVLLSGILANWLIGMATFLTTSARDVVGKILGTALPVILFVAGNFQHSAANMGYFSLGIL
TSDNYAWYEYILLNLIPASIGNIIGGAIFISLLFLYAFRKEMRS
>Mature_284_residues
MDDNGNKESTNQTKETKEIPERQFLFPVQVMQSFSNKGKEHLDTNTPSQLVLALKAGSFMTFGAVFSVLLAIGVDAKGLT
YILQGIGFTAGYLMVFMSQSVLFTEVNVLLPTYYLQKSYWIKHKFIKFWAVAYIGNLIGALFVALLIIISNSLTPEFSKE
LETLISHKMKFADYGWAGWFQVLLSGILANWLIGMATFLTTSARDVVGKILGTALPVILFVAGNFQHSAANMGYFSLGIL
TSDNYAWYEYILLNLIPASIGNIIGGAIFISLLFLYAFRKEMRS

Specific function: May act as a formate transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=282, Percent_Identity=26.5957446808511, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788837, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321779, Length=226, Percent_Identity=28.3185840707965, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: 1.2.1.2

Molecular weight: Translated: 31603; Mature: 31603

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9006048 [H]