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The map label for this gene is ade [C]

Identifier: 23098206

GI number: 23098206

Start: 800267

End: 802006

Strand: Direct

Name: ade [C]

Synonym: OB0751

Alternate gene names: 23098206

Gene position: 800267-802006 (Clockwise)

Preceding gene: 23098205

Following gene: 23098207

Centisome position: 22.04

GC content: 35.69

Gene sequence:

>1740_bases
ATGGAAAACGGAAGGAACTGGAGAAATCGCGAATTGCGCCAACATGTAAAGGTGATAGATGGAACAGTATCACCAACTTT
ACTTTTAAAGAATGCAACGTATTTAAACGTTCATACAAAACAATGGTTAGAGGCAAATATTTGGATTTATAAAGATCGGA
TTATATACGTAGGAGAAAAATTACCAAATCAATCGCAAGAGACAGAGGTTTATGATTGTGAAGGTAGGTTTGTTGTACCA
GGCTATATTGAGCCACATGCTCATCCATTCCAATTAGCAAATCCGGAGATAACAGCAATGCATGCAGCAAAAACAGGAAC
TACTACCCTCGTAAATGACAATTTGACATGGTATTTGCTAACTAATAAAAAGAAAGCGTTTTCTATCATTGATCAATTTA
ACAAATTACCTATTTCGATGTTTTGGTGGTCAAGGTATGATTCTCAGACAACCTTACAAGAAGAGAATCATTTTATTAAT
ACAAACGATGTGCTTGATTGGATAAATCATCCGTCTGTAGTACAAGGTGGAGAATTAACAGATTGGCCGAGTTTGTTAGC
TGGAGATGATCGACTATTATATTGGATTCAAGAGACAAAACGAAATGGAAAACCAATTGAAGGTCATCTACCAGGTGCAT
CATTACGAACATTAACAAAGATGAAGTTATTAGGAATTAGTGCTGATCATGAAGCAATGACTGGAAAAGATGTCATGAAT
CGTCTGCAGCTCGGATATATGGTTGGTCTACGTTATTCACCAATTCGACCTGATTTGCCTGCTATTTTAGAAGAATTATT
AGAGTCTGGGCTAACTACATTTGATCAACTTACATTTACCATGGATGGTCCAACTCCTTACTTTATGAAAGACGGGGTAA
TTAATACCTGTATTCAAATTGCTATCGATAAAGGAATTCCATTAGAAGATGCTTATCGCATGGGATCTTTTCATGCTGCA
AAACACCTGCGGATGGATGAGGAACTTGGAAGTATTGCACCAGGTAGAATCGCACATATTAACATTTTACAAGAAAAAGA
AAATCCAAATCCGATAGGTGTGCTTGCAAAGGGCGAATGGATTGTGAAAGAGACAAAGGAAATCGATATTCCATCAATTA
TTGATTGGAGTAAGTATGAGATTAATGAAATGAATATTGATTGGAATCTAACGGAAGATGATCTACAATTTTCTGTTCCA
GTTGGAATGGATGTAGTCAATGATGTCATTATTAAGCCTTATACAATTGATTCAGATGTTAGTTTTGAAGAATTAAATGA
AGAAAAGGGCGAACAATTTATCCTGCTAATAGATAGAAAAGGAAAATGGAGAGTAAATACGATTATTCGAGGGTTTGCGC
CGAAACTTGGGGCGCTCATAAGTAGTTACTCTGCATCGGGAGATATTATTATAATCGGAAATAGCAAAAAGGATATTTTT
ATTGCTTGGAATCGACTTAAAGAGATAAAAGGTGGCATTATTTTAGTTAATAATGGTGAAATATTGACGGAGATTCCATT
AACACTTGGAGGATCTCTGCCAAATGAGCCAATGGAACAAATGATAAAGTACGATAAACAATTAAAGGACACATTACAAA
AATATGGATTTGCCTTTTACGATCCAGTTTATAGTCTATTATTCTTGTCCGCTTTTCATCTACCTTTCTTTAGGATCACA
CAGAAGGGTCTATTGGATGTAAAAAATCGTGATATACTCTTTCCAGCAACGATGAGGTAG

Upstream 100 bases:

>100_bases
AATATTTGGTAAATTTTACTAAAATATACACATTCTTTACTTTATTAAAGCAATATATATGATAGAATAAAAGAAATTAT
AATTACTGGAGAGTTGCCGT

Downstream 100 bases:

>100_bases
CCTATAATAAAAGATAACTTAAGTACAAAAAGGTGTTGTCTATGAAAAGAGTAGGGTTCATTATATTGCTTATTATATCT
TTATTAATTGCTTGCGAAGA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MENGRNWRNRELRQHVKVIDGTVSPTLLLKNATYLNVHTKQWLEANIWIYKDRIIYVGEKLPNQSQETEVYDCEGRFVVP
GYIEPHAHPFQLANPEITAMHAAKTGTTTLVNDNLTWYLLTNKKKAFSIIDQFNKLPISMFWWSRYDSQTTLQEENHFIN
TNDVLDWINHPSVVQGGELTDWPSLLAGDDRLLYWIQETKRNGKPIEGHLPGASLRTLTKMKLLGISADHEAMTGKDVMN
RLQLGYMVGLRYSPIRPDLPAILEELLESGLTTFDQLTFTMDGPTPYFMKDGVINTCIQIAIDKGIPLEDAYRMGSFHAA
KHLRMDEELGSIAPGRIAHINILQEKENPNPIGVLAKGEWIVKETKEIDIPSIIDWSKYEINEMNIDWNLTEDDLQFSVP
VGMDVVNDVIIKPYTIDSDVSFEELNEEKGEQFILLIDRKGKWRVNTIIRGFAPKLGALISSYSASGDIIIIGNSKKDIF
IAWNRLKEIKGGIILVNNGEILTEIPLTLGGSLPNEPMEQMIKYDKQLKDTLQKYGFAFYDPVYSLLFLSAFHLPFFRIT
QKGLLDVKNRDILFPATMR

Sequences:

>Translated_579_residues
MENGRNWRNRELRQHVKVIDGTVSPTLLLKNATYLNVHTKQWLEANIWIYKDRIIYVGEKLPNQSQETEVYDCEGRFVVP
GYIEPHAHPFQLANPEITAMHAAKTGTTTLVNDNLTWYLLTNKKKAFSIIDQFNKLPISMFWWSRYDSQTTLQEENHFIN
TNDVLDWINHPSVVQGGELTDWPSLLAGDDRLLYWIQETKRNGKPIEGHLPGASLRTLTKMKLLGISADHEAMTGKDVMN
RLQLGYMVGLRYSPIRPDLPAILEELLESGLTTFDQLTFTMDGPTPYFMKDGVINTCIQIAIDKGIPLEDAYRMGSFHAA
KHLRMDEELGSIAPGRIAHINILQEKENPNPIGVLAKGEWIVKETKEIDIPSIIDWSKYEINEMNIDWNLTEDDLQFSVP
VGMDVVNDVIIKPYTIDSDVSFEELNEEKGEQFILLIDRKGKWRVNTIIRGFAPKLGALISSYSASGDIIIIGNSKKDIF
IAWNRLKEIKGGIILVNNGEILTEIPLTLGGSLPNEPMEQMIKYDKQLKDTLQKYGFAFYDPVYSLLFLSAFHLPFFRIT
QKGLLDVKNRDILFPATMR
>Mature_579_residues
MENGRNWRNRELRQHVKVIDGTVSPTLLLKNATYLNVHTKQWLEANIWIYKDRIIYVGEKLPNQSQETEVYDCEGRFVVP
GYIEPHAHPFQLANPEITAMHAAKTGTTTLVNDNLTWYLLTNKKKAFSIIDQFNKLPISMFWWSRYDSQTTLQEENHFIN
TNDVLDWINHPSVVQGGELTDWPSLLAGDDRLLYWIQETKRNGKPIEGHLPGASLRTLTKMKLLGISADHEAMTGKDVMN
RLQLGYMVGLRYSPIRPDLPAILEELLESGLTTFDQLTFTMDGPTPYFMKDGVINTCIQIAIDKGIPLEDAYRMGSFHAA
KHLRMDEELGSIAPGRIAHINILQEKENPNPIGVLAKGEWIVKETKEIDIPSIIDWSKYEINEMNIDWNLTEDDLQFSVP
VGMDVVNDVIIKPYTIDSDVSFEELNEEKGEQFILLIDRKGKWRVNTIIRGFAPKLGALISSYSASGDIIIIGNSKKDIF
IAWNRLKEIKGGIILVNNGEILTEIPLTLGGSLPNEPMEQMIKYDKQLKDTLQKYGFAFYDPVYSLLFLSAFHLPFFRIT
QKGLLDVKNRDILFPATMR

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=578, Percent_Identity=22.6643598615917, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y751_OCEIH (Q8ES91)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691672.1
- ProteinModelPortal:   Q8ES91
- GeneID:   1016277
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0751
- NMPDR:   fig|221109.1.peg.759
- HOGENOM:   HBG725357
- ProtClustDB:   CLSK872774
- BioCyc:   OIHE221109:OB0751-MONOMER
- BRENDA:   3.5.4.2
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 66115; Mature: 66115

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENGRNWRNRELRQHVKVIDGTVSPTLLLKNATYLNVHTKQWLEANIWIYKDRIIYVGEK
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEHHHHEEEEEEEEEEEEEEEECC
LPNQSQETEVYDCEGRFVVPGYIEPHAHPFQLANPEITAMHAAKTGTTTLVNDNLTWYLL
CCCCCCCCEEEECCCCEEECCCCCCCCCCEEECCCCEEEEEECCCCCEEEEECCEEEEEE
TNKKKAFSIIDQFNKLPISMFWWSRYDSQTTLQEENHFINTNDVLDWINHPSVVQGGELT
ECCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHHHCCCCCEECCCCCC
DWPSLLAGDDRLLYWIQETKRNGKPIEGHLPGASLRTLTKMKLLGISADHEAMTGKDVMN
CCCHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHH
RLQLGYMVGLRYSPIRPDLPAILEELLESGLTTFDQLTFTMDGPTPYFMKDGVINTCIQI
HHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHCCHHHHEEHE
AIDKGIPLEDAYRMGSFHAAKHLRMDEELGSIAPGRIAHINILQEKENPNPIGVLAKGEW
EECCCCCHHHHHHCCCHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCE
IVKETKEIDIPSIIDWSKYEINEMNIDWNLTEDDLQFSVPVGMDVVNDVIIKPYTIDSDV
EEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEECCCCHHHHHHHEECCEECCCCC
SFEELNEEKGEQFILLIDRKGKWRVNTIIRGFAPKLGALISSYSASGDIIIIGNSKKDIF
CHHHHHHCCCCEEEEEEECCCCEEEHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCEEE
IAWNRLKEIKGGIILVNNGEILTEIPLTLGGSLPNEPMEQMIKYDKQLKDTLQKYGFAFY
EEEHHHHHHCCCEEEEECCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DPVYSLLFLSAFHLPFFRITQKGLLDVKNRDILFPATMR
HHHHHHHHHHHHCCCHHEECCCCCEEECCCCEEECCCCC
>Mature Secondary Structure
MENGRNWRNRELRQHVKVIDGTVSPTLLLKNATYLNVHTKQWLEANIWIYKDRIIYVGEK
CCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEHHHHEEEEEEEEEEEEEEEECC
LPNQSQETEVYDCEGRFVVPGYIEPHAHPFQLANPEITAMHAAKTGTTTLVNDNLTWYLL
CCCCCCCCEEEECCCCEEECCCCCCCCCCEEECCCCEEEEEECCCCCEEEEECCEEEEEE
TNKKKAFSIIDQFNKLPISMFWWSRYDSQTTLQEENHFINTNDVLDWINHPSVVQGGELT
ECCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCHHHHHHCCCCCEECCCCCC
DWPSLLAGDDRLLYWIQETKRNGKPIEGHLPGASLRTLTKMKLLGISADHEAMTGKDVMN
CCCHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHH
RLQLGYMVGLRYSPIRPDLPAILEELLESGLTTFDQLTFTMDGPTPYFMKDGVINTCIQI
HHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHCCHHHHEEHE
AIDKGIPLEDAYRMGSFHAAKHLRMDEELGSIAPGRIAHINILQEKENPNPIGVLAKGEW
EECCCCCHHHHHHCCCHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCE
IVKETKEIDIPSIIDWSKYEINEMNIDWNLTEDDLQFSVPVGMDVVNDVIIKPYTIDSDV
EEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEECCCCHHHHHHHEECCEECCCCC
SFEELNEEKGEQFILLIDRKGKWRVNTIIRGFAPKLGALISSYSASGDIIIIGNSKKDIF
CHHHHHHCCCCEEEEEEECCCCEEEHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCEEE
IAWNRLKEIKGGIILVNNGEILTEIPLTLGGSLPNEPMEQMIKYDKQLKDTLQKYGFAFY
EEEHHHHHHCCCEEEEECCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DPVYSLLFLSAFHLPFFRITQKGLLDVKNRDILFPATMR
HHHHHHHHHHHHCCCHHEECCCCCEEECCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376