Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 23097988

GI number: 23097988

Start: 565839

End: 566417

Strand: Direct

Name: guaA [H]

Synonym: OB0533

Alternate gene names: 23097988

Gene position: 565839-566417 (Clockwise)

Preceding gene: 23097987

Following gene: 23097990

Centisome position: 15.59

GC content: 34.72

Gene sequence:

>579_bases
ATGTTAAAACGGTGTGGCTGGGTTACTGACGAATCCATCTATATTTCTTATCATGATGAAGAATGGGGAGTTCCTGTTTA
TACGGATGACAGGTATCTATTTGAAATGTTGTCGTTAGAAGGAGCTCAAGCAGGGTTAAGTTGGATTACGATTCTAAAAA
GACGAGAGAATTATAGAGAAGCATTTGACCATTTTTATCCGGAAATTGTGGCAACCTATTCGGATGAAAAAATAGAAACA
TTACTATCAAATGAAGGTATTATTCGAAATAGAAAAAAGGTAAGTTCGGTGATTAATAATGCCCATAGATGCATGGAAGT
CGCTAAGGAATTTGGTTCTTTTCATAACTATATTTGGAGTTTTGTGGATGGACAACCAATTATGAATACGTGGGAAAACG
ATAAGGAAATTCCTGCTTATACGGACCTTTCCAAAAAGATGAGTAAAGATATGAAAAAAAGAGGTTTTCGCTTTGTAGGT
CCAACTATCTGTTATTCATTTATGCAAGCAACTGGAATGGTGAATGACCATACAAAGCAATGTTTCTTATACCATGGTAA
TCAAGAAAATAAAGATTAA

Upstream 100 bases:

>100_bases
AGGCAGCAGGGTTTCACAATGTGAAATTGTATCCTGGTAGTTTTAGTGATTGGATATCATATGATGAAAACGATGTGAAA
GTAGGAGAGGAGACCACGTA

Downstream 100 bases:

>100_bases
CTCTTTCTTCAATTGTTTTTAAGCTAAAAACCGAACTACAATCCAGTCACATCGTTCACTCCTTCTCGAATTTTTACTTC
GATTCGTGTAGAGTTAAGCT

Product: 3-methyladenine-DNA glycosylase I

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLKRCGWVTDESIYISYHDEEWGVPVYTDDRYLFEMLSLEGAQAGLSWITILKRRENYREAFDHFYPEIVATYSDEKIET
LLSNEGIIRNRKKVSSVINNAHRCMEVAKEFGSFHNYIWSFVDGQPIMNTWENDKEIPAYTDLSKKMSKDMKKRGFRFVG
PTICYSFMQATGMVNDHTKQCFLYHGNQENKD

Sequences:

>Translated_192_residues
MLKRCGWVTDESIYISYHDEEWGVPVYTDDRYLFEMLSLEGAQAGLSWITILKRRENYREAFDHFYPEIVATYSDEKIET
LLSNEGIIRNRKKVSSVINNAHRCMEVAKEFGSFHNYIWSFVDGQPIMNTWENDKEIPAYTDLSKKMSKDMKKRGFRFVG
PTICYSFMQATGMVNDHTKQCFLYHGNQENKD
>Mature_192_residues
MLKRCGWVTDESIYISYHDEEWGVPVYTDDRYLFEMLSLEGAQAGLSWITILKRRENYREAFDHFYPEIVATYSDEKIET
LLSNEGIIRNRKKVSSVINNAHRCMEVAKEFGSFHNYIWSFVDGQPIMNTWENDKEIPAYTDLSKKMSKDMKKRGFRFVG
PTICYSFMQATGMVNDHTKQCFLYHGNQENKD

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=187, Percent_Identity=51.3368983957219, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 22619; Mature: 22619

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRCGWVTDESIYISYHDEEWGVPVYTDDRYLFEMLSLEGAQAGLSWITILKRRENYRE
CCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AFDHFYPEIVATYSDEKIETLLSNEGIIRNRKKVSSVINNAHRCMEVAKEFGSFHNYIWS
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDGQPIMNTWENDKEIPAYTDLSKKMSKDMKKRGFRFVGPTICYSFMQATGMVNDHTKQ
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCE
CFLYHGNQENKD
EEEEECCCCCCC
>Mature Secondary Structure
MLKRCGWVTDESIYISYHDEEWGVPVYTDDRYLFEMLSLEGAQAGLSWITILKRRENYRE
CCCCCCCCCCCEEEEEEECCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AFDHFYPEIVATYSDEKIETLLSNEGIIRNRKKVSSVINNAHRCMEVAKEFGSFHNYIWS
HHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDGQPIMNTWENDKEIPAYTDLSKKMSKDMKKRGFRFVGPTICYSFMQATGMVNDHTKQ
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCE
CFLYHGNQENKD
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]