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The map label for this gene is ectC

Identifier: 23097974

GI number: 23097974

Start: 552304

End: 552690

Strand: Direct

Name: ectC

Synonym: OB0519

Alternate gene names: 23097974

Gene position: 552304-552690 (Clockwise)

Preceding gene: 23097973

Following gene: 23097975

Centisome position: 15.21

GC content: 37.98

Gene sequence:

>387_bases
ATGATCGTAAAATCATTAGAAGACATTCAAGGTACAGAGGATCATCAAAAAGGGGAAACATGGGAAAGCAGACGTTTTGT
TTTAAATAAAGACAATGTTGGCTTTAGCCTTAACGATACGATTATTAAGGCAGGAACAGAAAGCTACTTCTGGTACAAAA
ATCATATTGAAGCAGTGTACTGCATCGAAGGTGAAGGGGAAGTAGAGAAAAAAGATACTGGTGAGGTATGGCAGTTGAAG
CCAGGAACGATGTATCTTTTAAATGATAACGATAAGCACTATTTACGTGCAAAAACTCAAATGCGTATGGTATGTGTGTT
CAACCCTGCGTTAGTAGGAACGGAAACACATGATGAAGATGGGGTATACCCATTATTAGCTGAATAA

Upstream 100 bases:

>100_bases
TCCGCCATTAATTATTGATGAAGATGGTATTGAAAAAGGAATGGACATCTTAGAAGAAAGTATTCAAGCAGCACTAGAGA
AATAAGGAGGAATTTTAATC

Downstream 100 bases:

>100_bases
TAAAAGATTAAAAGGACCCTGACTTCTCAAAGGAGGAGGAGGGTTCTTTTTTTTTGAAAATAAAAGGGTTGTAAATTGTG
TCAAAAAAGACTACAATTTA

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVYCIEGEGEVEKKDTGEVWQLK
PGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDEDGVYPLLAE

Sequences:

>Translated_128_residues
MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVYCIEGEGEVEKKDTGEVWQLK
PGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDEDGVYPLLAE
>Mature_128_residues
MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVYCIEGEGEVEKKDTGEVWQLK
PGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDEDGVYPLLAE

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECTC_OCEIH (Q8ESU7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_691440.1
- ProteinModelPortal:   Q8ESU7
- GeneID:   1015789
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB0519
- NMPDR:   fig|221109.1.peg.522
- HOGENOM:   HBG294526
- OMA:   DENGVYP
- ProtClustDB:   PRK13290
- BioCyc:   OIHE221109:OB0519-MONOMER
- BRENDA:   4.2.1.108
- HAMAP:   MF_01255
- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- ProDom:   PD080544

Pfam domain/function: PF06339 Ectoine_synth; SSF51182 RmlC_like_cupin

EC number: =4.2.1.108

Molecular weight: Translated: 14763; Mature: 14763

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVY
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCEEEECCCCCEEEECCCCCEEE
CIEGEGEVEKKDTGEVWQLKPGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDED
EECCCCCCCCCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEEEECCEEECCCCCCCC
GVYPLLAE
CEEEEECC
>Mature Secondary Structure
MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVY
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCEEEECCCCCEEEECCCCCEEE
CIEGEGEVEKKDTGEVWQLKPGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDED
EECCCCCCCCCCCCCEEEECCCEEEEEECCCCEEEEECCCEEEEEEECCEEECCCCCCCC
GVYPLLAE
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376