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The map label for this gene is frwC [H]

Identifier: 229013120

GI number: 229013120

Start: 4199197

End: 4200279

Strand: Direct

Name: frwC [H]

Synonym: y3777

Alternate gene names: 229013120

Gene position: 4199197-4200279 (Clockwise)

Preceding gene: 22127646

Following gene: 22127650

Centisome position: 91.27

GC content: 53.74

Gene sequence:

>1083_bases
ATGAAAGAGCTGATAAATATACTTAAAAATACGCGCCAACATCTGATGACGGGCGTTTCATATATGATCCCTTTTGTGGT
TGCTGGCGGTATTTTGCTAGCACTTTCTGTGATGCTTTACGGTAAAGGTGCGGTGCCAGAGGTTGCCAGTGACCCTAATT
TGAAAAAGCTATTCGATATTGGTGTCGTGGGCTTGACGTTGATGGTGCCATTTTTGGCAGCCTATATCGGTTACGCCATT
GCGGATCGTGCGGCGCTCGCCCCGGCGGCTATCGGTGCTTGGGTAGGGGCTTCTTTCGGGGCTGGTTTTTTTGGTGCCAT
TATCGCGGGCTTGCTGGGCGGTATTATCGTTTTCTATCTGAAGAAGATCTCCGTGCCAAAGACGCTGCGTTCGGTGATGC
CGATCTTCGTGATCCCGATCGTCGGTACCCTTCTCACCGCTGGGATCATGATGTGGGGCTTGGGTGAACCCATCGGCATC
CTGACAGCCAACCTCACGCAATGGCTACAGGGTATGCAGCAAGGAAGCGTTATATTACTGGCAATTATTATGGGCCTGAT
GCTGGCGTTTGACATGGGCGGGCCGGTCAACAAGGTGGCTTATGCCTTTATGTTGATCTGTGTGGCGCAGGGTGTTTATA
CCTTGGTGGCCGTCGCCGCCGTCGCCATTGCAACCCCGCCGTTGGGCATGGGCCTTGCCACGCTGATTGGCCGTAAATAT
TACTCGGTGGAAGAACGTGAAGCAGGTAAGGCCGCGATGCTGATGGGCTGCGTTGGCATTACTGAGGGGGCCATCCCGTT
TGCCGCCGCCGATCCACTGCGTGTCATTCCTGCCAATATGATCGGTTCCGCCTGCGCCGCCGTAACTGCCGTGTTGTTCG
GTGTCCAGTGCTATGCCGCTTGGGGAGGGTTGATCGTGCTACCGGTGGTCGACGGTAAACTGGGCTTTGTGGTGGCCTTG
TTAGTCGGCATGGTCGTTACCGCGTTGATAGCCAATCTATTAAAGCGTTTCACCGCCCAAAAGCAGCCGGGAAGGTCATC
AGCAGAGGGCGATGTGAACATGGATTTCGATATTAAAAATTAG

Upstream 100 bases:

>100_bases
CCAACAGCATCAAAAACATTTCGCGATTTCAATATTAAGGGGAATAAGCCCTGACGCCTGCGGAACTCATCGCACACGGA
TGAACGCTATGGAGTGAATG

Downstream 100 bases:

>100_bases
CGGTACACCCGATGAGCGTTATTTATTTTAAGGTCAACGACATTTTAAGGTCAACAACCGGTAAGTGATTCGGGCGAGTG
AGCGCAGCTAACACCCCTGT

Product: putative fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAAVAIATPPLGMGLATLIGRKY
YSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGFVVAL
LVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN

Sequences:

>Translated_360_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAAVAIATPPLGMGLATLIGRKY
YSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGFVVAL
LVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN
>Mature_360_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAAVAIATPPLGMGLATLIGRKY
YSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGFVVAL
LVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=359, Percent_Identity=76.3231197771588, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1788492, Length=329, Percent_Identity=40.7294832826748, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786951, Length=278, Percent_Identity=36.6906474820144, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87082348, Length=298, Percent_Identity=36.5771812080537, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788729, Length=372, Percent_Identity=25.5376344086022, Blast_Score=107, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37453; Mature: 37453

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVVGLTLMVPFLAAYIGYAIADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGILTANLTQWLQGMQQGSVILL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAAVAIATPPLGMGLATLIGRKY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAA
CCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WGGLIVLPVVDGKLGFVVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN
HCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVVGLTLMVPFLAAYIGYAIADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGILTANLTQWLQGMQQGSVILL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAAVAIATPPLGMGLATLIGRKY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAA
CCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
WGGLIVLPVVDGKLGFVVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN
HCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]