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The map label for this gene is ompR [H]

Identifier: 22127742

GI number: 22127742

Start: 4313033

End: 4313770

Strand: Reverse

Name: ompR [H]

Synonym: y3871

Alternate gene names: 22127742

Gene position: 4313770-4313033 (Counterclockwise)

Preceding gene: 22127746

Following gene: 22127735

Centisome position: 93.76

GC content: 50.81

Gene sequence:

>738_bases
ATGAAACCTGCAATCCTCGTGGTGGATGACGATACGGCCATCTGTGAAGTGCTGCGAGATGTACTTAACGAACACGTATT
CGATGTACTGTTATGCCACAGCGGCAATGAGGCGCTTCAGATTACCGCTACACAGCCCTCAATCGCACTTATTTTGCTTG
ATATGATGCTGCCGGATATCAATGGCCTGTTGGTGTTGCAGCAAGTGCAAAAACTGCGCCCGTCGCTACCGGTCGTGATG
CTCACCGGCATGGGTAGTGAGTCTGATATGGTGGTTGGGCTAGAAATGGGGGCGGACGACTATATCGCTAAACCATTTAA
TGCCAGGGTAGTGGTCGCACGCGTTAAAGCGGTGTTGCGGCGGAGCGAGGTGTTGGCGATAGAAAGTAGCAGTGTGATAG
AAAGTAGCAGTGTGAAAGCCTGCGGATTGCAATTTAATGGCTGGCGGCTGAATACCGACCGCTGTCAGTTGATGAACCCA
CAGCAGCAGCAAATCGATTTGACTCAGGGGGAATATGGCCTGCTGCTGTCGTTGATGCAAAACGCCAGAAAAGTGCTCTC
TCGTGAAAAGCTGCTTGAACTGACGCACCGTGAAAGCCTGGACGTTTTTGATCGCACTATTGATGTACTGATTATGCGGT
TACGTCGAAAAATAGAAGTTAATCCGCACCAGCCCACACTGATCCGTACCATCCGCGGCGTGGGGTATGTCTTTGCCGCC
GATATTATTCATGCCTAG

Upstream 100 bases:

>100_bases
TGACAGCAGTTGAAAATTCAACACAGCTCGGTGTCATTTATACGGCTGGCAATCAACAATCGGATACACTTGTCAACACC
CCTCACCTCTGGAAAAAATA

Downstream 100 bases:

>100_bases
AATAATGTGGCCTAATAAGATGGGCTTAAGACGCTCTCCCCATCGGGCTATCTTATTTACCTGTTTGCAACATTATCCGT
TTGCAACATTACCCACTTGC

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVIESSSVKACGLQFNGWRLNTDRCQLMNP
QQQQIDLTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAA
DIIHA

Sequences:

>Translated_245_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVIESSSVKACGLQFNGWRLNTDRCQLMNP
QQQQIDLTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAA
DIIHA
>Mature_245_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVIESSSVKACGLQFNGWRLNTDRCQLMNP
QQQQIDLTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAA
DIIHA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=37.1308016877637, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=36.5145228215768, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=36.8200836820084, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=36.5546218487395, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=36.0169491525424, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=243, Percent_Identity=34.5679012345679, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790860, Length=237, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=33.7606837606838, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082012, Length=236, Percent_Identity=32.2033898305085, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=31.7796610169492, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=32.3404255319149, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=28.6324786324786, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789402, Length=236, Percent_Identity=29.2372881355932, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=31.3807531380753, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=31.2977099236641, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27336; Mature: 27336

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCC
NGLLVLQQVQKLRPSLPVVMLTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHH
RSEVLAIESSSVIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQIDLTQGEYGLLLSLMQ
HHHEEEEECCCCCCCCCCCEECEEECCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHH
NARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DIIHA
HHHCC
>Mature Secondary Structure
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCC
NGLLVLQQVQKLRPSLPVVMLTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHH
RSEVLAIESSSVIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQIDLTQGEYGLLLSLMQ
HHHEEEEECCCCCCCCCCCEECEEECCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHH
NARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAA
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
DIIHA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]