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The map label for this gene is lsrC [H]

Identifier: 22127641

GI number: 22127641

Start: 4190997

End: 4192052

Strand: Direct

Name: lsrC [H]

Synonym: y3770

Alternate gene names: 22127641

Gene position: 4190997-4192052 (Clockwise)

Preceding gene: 22127640

Following gene: 22127642

Centisome position: 91.09

GC content: 53.22

Gene sequence:

>1056_bases
ATGCTGAAATTTATTCAGAATAATCGTGAAGGTACCGCGCTACTGGCCATTCTCACCCTATTTGCCCTATTGGGGATTAT
TGACCGCAACTATTTCAGCTTGCAGACCTTCACCATGATTTTCAGCAGCGCACAGATCCTGATCCTGCTGGCCATCGGGG
CCACCCTGGTGATGTTGACCCGCAATATCGACGTTTCCGTGGGCTCCATCACCGGTTTATGCGCGGTGACCGTCGGTATG
GCGCTGAATGCCGGTTTTGGCCTGGCGGCATCTTGCTTGTTCGCCTTGTTGGTTGGCATGGTAGCGGGCTTTTTTAACGG
CATTCTGGTGACCTGGTTGCGCATTCCGGCCATTGTCGCCACGCTAGGTACGCTTGGGTTATACCGTGGCCTGATGCTAC
TGCTAACAGGCGGTAAGTGGATCGAAGGATTACCGGCGGACCTGAAAAGTTTATCAACCCCTATTCTGTTTTCTATCTCG
CCCATTGGCTGGCTAACGATGTTGCTGATCCTTGCGATGGCCTGGCTGTTGGGCAAAACCGCCTTTGGCCGCAGTTTCTA
TGCCACGGGGGATAACTTACAAGGGGCGCGTCAGTTGGGGGTCCGTACCGACAGCCTCCGCATTTTTGCCTTTTCAATGA
ACGGCGTGATGGCCGCACTGGCTGGGATCGTCTTCGCTTCCCAAATTGGCTTTATCCCTAACCAAACAGGCAACGGGCTG
GAAATGAAGGCCATTGCCGCCTGCGTGTTGGGCGGGATCAGCCTGCTTGGTGGGACGGGGACCATTATTGGTGCCATTTT
GGGCGCTTTCCTGCTGACACAAATCGATAGCGTACTGGTGTTACTGCGCCTACCGGCCTGGTGGAATGACTTTATTGCCG
GTTTGGTGCTGCTGGGGGTGTTGGTATTCGATGGCCGTCTGCGTTGTGCTGTTGAGCGTAATATCCGCCAACAGAAATAT
GCCCGCTTCACTGCCCAAGCCATTATTAGTGATAAAAAACCAACCGTTAGCGATAACAACCCAGCAGCTAGCAATAAAAA
GAAGGCGGCATTATGA

Upstream 100 bases:

>100_bases
TGAATGTCGATACCATCATGCATATGGCGTTTGGTGAGCACCGTTCTGCGAGTGAACCTCAGGGCGGCACCGCCTCCTCG
GCTGAAAATAAGGGCGCATC

Downstream 100 bases:

>100_bases
ATCTCTACCGACGTTATGGATGGGAACTGACTCTGGCGGCGCTGCTGGTGCTGGAAATCCTGCTATTTGGTTTATCGAAT
TCGCGCATGTTGGATATCAA

Product: ABC transport system permease

Products: NA

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVTVGM
ALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVATLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSIS
PIGWLTMLLILAMAWLLGKTAFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGL
EMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGVLVFDGRLRCAVERNIRQQKY
ARFTAQAIISDKKPTVSDNNPAASNKKKAAL

Sequences:

>Translated_351_residues
MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVTVGM
ALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVATLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSIS
PIGWLTMLLILAMAWLLGKTAFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGL
EMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGVLVFDGRLRCAVERNIRQQKY
ARFTAQAIISDKKPTVSDNNPAASNKKKAAL
>Mature_351_residues
MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVTVGM
ALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVATLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSIS
PIGWLTMLLILAMAWLLGKTAFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGL
EMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGVLVFDGRLRCAVERNIRQQKY
ARFTAQAIISDKKPTVSDNNPAASNKKKAAL

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787793, Length=350, Percent_Identity=75.7142857142857, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1790191, Length=311, Percent_Identity=31.5112540192926, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789992, Length=348, Percent_Identity=27.0114942528736, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI145693152, Length=267, Percent_Identity=31.0861423220974, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788896, Length=304, Percent_Identity=30.2631578947368, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790524, Length=301, Percent_Identity=27.906976744186, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082395, Length=306, Percent_Identity=31.0457516339869, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693214, Length=283, Percent_Identity=34.6289752650177, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787794, Length=293, Percent_Identity=28.6689419795222, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788471, Length=331, Percent_Identity=28.3987915407855, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 37248; Mature: 37248

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGLCAVTVGMALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVA
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSISPIGWLTMLLILAMAWLLGKT
HHHHHHHHHHHHHHHCCCCHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGL
HCCCCEECCCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCAVERNIRQQKYARFTAQAIISDKKPTVSDNNPAASNKKKAAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGLCAVTVGMALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVA
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSISPIGWLTMLLILAMAWLLGKT
HHHHHHHHHHHHHHHCCCCHHCCCCHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGL
HCCCCEECCCCCCCHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCAVERNIRQQKYARFTAQAIISDKKPTVSDNNPAASNKKKAAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA