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The map label for this gene is lsrD [H]

Identifier: 22127642

GI number: 22127642

Start: 4192049

End: 4193050

Strand: Direct

Name: lsrD [H]

Synonym: y3771

Alternate gene names: 22127642

Gene position: 4192049-4193050 (Clockwise)

Preceding gene: 22127641

Following gene: 22127643

Centisome position: 91.12

GC content: 54.79

Gene sequence:

>1002_bases
ATGAATCTCTACCGACGTTATGGATGGGAACTGACTCTGGCGGCGCTGCTGGTGCTGGAAATCCTGCTATTTGGTTTATC
GAATTCGCGCATGTTGGATATCAATGTGCTGCTGTTCAGCACCAGTGATTTTATCTGCATCGGGATCGTGGCGCTGCCAT
TGACCATGGTGATTGTCAGTGGCGGCATCGATATTTCATTCGGTTCGACTATCGGGTTGTGCGCCATATTTCTGGGCATT
GTATTTCAGGCGGGCGTGCCGATGAGTGTGGCTATCCCACTGACAGTGCTCGTCGGCGCACTGTGTGGGTTAATTAATGC
CGGATTGATCCTCTATACCGGCGTCAACCCCTTGGTCATCACGCTCGGCACCCTGTATCTGTTCGGTGGCAGTGCCCTGC
TGTTATCCGGCCTCTCCGGTGCGACAGGCTATGAAGGGATTGGCGGTTTCCCGGCCGCTTTTACTGATTTCGCCAACCAA
ACCCTCTTCGGGCTGCCAATCCCCCTGGTGATATTTATGCTGTGTGTTCTGCTGTTCTGGCTGCTGATGCACCGTACTCA
CAGCGGCCGCCACGTGTTCCTGATTGGACAAAGCAGCCGAGTCGCCCGTTACAGTGCCCTGCCCATCGCCCGCACCTTAT
GCATGCTGTATGCCATGACCGGGGTGGCCTCAGCGATTTCCGCCATTCTGCTGGTGTCTTATTTCGGCTCCGCACGCTCT
GATTTAGGTGCCTCATTCCTGATGCCGGCGATCACCGCCGTGGTATTGGGAGGGGCCAATATTTACGGGGGATCCGGCTC
CATTCTTGGAACTGCCTTGGCGGTATTACTGGTCGGGTACCTGCAACAAGGTCTGCAAATGATTGGTACGCCAAACCAAA
TTTCCAGTGCGCTGTCTGGGGCATTGCTGATTCTGGTGGTGGTTGGGCGATCGATCAGTCTGCACAGGCATTTGATTTAT
GAATGGCTACAACGTCGTCGCAGTCGAAAGGCCTCTGCGTGA

Upstream 100 bases:

>100_bases
AGAAATATGCCCGCTTCACTGCCCAAGCCATTATTAGTGATAAAAAACCAACCGTTAGCGATAACAACCCAGCAGCTAGC
AATAAAAAGAAGGCGGCATT

Downstream 100 bases:

>100_bases
TACCTAAACCCAACACCCAACACCCAACACCCAACACCCAACAAGACAGTGATTCGGAGATAGCAATGAGAACACAAAGA
TTAAAAAAATTAGCACTGGT

Product: ABC transport system permease

Products: NA

Alternate protein names: AI-2 import system permease protein lsrD [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA

Sequences:

>Translated_333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA
>Mature_333_residues
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIFLGI
VFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVITLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQ
TLFGLPIPLVIFMLCVLLFWLLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARS
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIY
EWLQRRRSRKASA

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787794, Length=325, Percent_Identity=80.3076923076923, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1790524, Length=251, Percent_Identity=28.2868525896414, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693152, Length=241, Percent_Identity=28.6307053941909, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788896, Length=312, Percent_Identity=26.6025641025641, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790191, Length=313, Percent_Identity=28.7539936102236, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788471, Length=221, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787793, Length=311, Percent_Identity=29.5819935691318, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082395, Length=313, Percent_Identity=26.517571884984, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789992, Length=137, Percent_Identity=29.9270072992701, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693214, Length=274, Percent_Identity=26.2773722627737, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35135; Mature: 35135

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVS
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
GGIDISFGSTIGLCAIFLGIVFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVI
CCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHH
TLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQTLFGLPIPLVIFMLCVLLFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARS
HHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSG
HCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALLILVVVGRSISLHRHLIYEWLQRRRSRKASA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLYRRYGWELTLAALLVLEILLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVS
CCCHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
GGIDISFGSTIGLCAIFLGIVFQAGVPMSVAIPLTVLVGALCGLINAGLILYTGVNPLVI
CCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHH
TLGTLYLFGGSALLLSGLSGATGYEGIGGFPAAFTDFANQTLFGLPIPLVIFMLCVLLFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHRTHSGRHVFLIGQSSRVARYSALPIARTLCMLYAMTGVASAISAILLVSYFGSARS
HHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSG
HCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALLILVVVGRSISLHRHLIYEWLQRRRSRKASA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA