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The map label for this gene is fadH [H]

Identifier: 22127463

GI number: 22127463

Start: 3981171

End: 3983219

Strand: Direct

Name: fadH [H]

Synonym: y3589

Alternate gene names: 22127463

Gene position: 3981171-3983219 (Clockwise)

Preceding gene: 22127462

Following gene: 22127465

Centisome position: 86.53

GC content: 52.95

Gene sequence:

>2049_bases
TTGGTTGTATGCCTGATGGAGACTGCAATGTTAGCTTACCCTCACCTGTTCACCCCGCTTGATCTTGGCTTTACCACACT
GAAAAATCGTATCTTAATGGGTTCTATGCATACTGGGTTGGAGGAGTTACCCGATGGCCCGCAACGTCTGGCGGCATTTT
ATGCCGAACGCGCAGCAGGCGGTGTCGGCCTGATTGTGACTGGCGGTATTGCCCCCAATATGAAAGGGGGGGTGTATCAG
GGCGCATCGGTACTGAATGACGCCGCGCAAATCCCCCATCACCAGGTGGTGACAGAGGCGGTTCATCAAGCTGGAGGGAA
AATCGCGCTACAAATTCTCCATGCGGGGCGTTACAGCTACCAGAAACACCCGGTAGCCCCTTCTGCGTTACAAGCGCCTA
TCAACCCTTTTGTACCACAAGCATTGAGCCATGAAGAGATCCTGCAAACTATTGCTGATTTCGCCCACTGTGCGCAATTA
GCCAAGCAAGCCGGTTACGACGGTGTCGAAATCATGGGTTCCGAAGGTTATCTGATCAACCAGTTTCTCACCGCCCGTAC
TAATCAGCGCGATGATGAATGGGGCGGTGATTTTACGCACCGAATGCGTTTTGCCGTAGAAATCGTGCGTGCCGTCCGTC
AGGCCACGGGACACGACTTTATTCTAATTTACCGTTTATCCATGCTTGATCTGGTGGAGGAAGGCTCCAACTGGGTAGAA
ATCGAGCAATTGGCACAGGCCGTTGAACAAGCAGGGGCAACGGTGATCAATACCGGTATCGGCTGGCATGAAGCCCGTAT
TCCCACCATCGCCACAATGGTGCCACGGGCCGGATTCAGTTGGGTGACCCGCAAGTTGATGGGGAAAGTGAATATCCCGC
TGATCACCACTAACCGAATTAATGACCCCGCCGTCGCAGAACAAGTGCTGGCCGATGGCTGTGCAGATATGGTGTCAATG
GCTCGGCCATTCCTGGCTGATGCCGCTTTTGTACAAAAAGCGGCACAGGGCCGGGCCGATGAAATTAACACCTGTATTGG
TTGTAATCAGGCCTGCCTGGACCAGATTTTTGACGGCAAACTGACCTCATGTTTGGTCAATCCCCGTGCTTGCCGCGAAA
CCGAAATGCCCGAATTACCCACAGACGCACCAAAACGGTTAGCGGTAGTCGGTGCCGGGCCTGCGGGGTTGGCTTTTGCG
GTAACCGCCGCCCGTCGCGGCCATCAGGTGACATTATTTGATGCTGCCGCAGAGATCGGCGGCCAATTTAATATTGCCAA
ACAGATCCCCGGCAAAGAGGAATTTTACGAAACCCTGCGCTATTTCCGCCGTCAATTAGTGCTGAACGGCGTCACCCTAC
AATTGAATACCCTGGTGCAGGTAAAGCAGTTGGCTGAGTTTGATGAAGTGATCCTCGCCTGTGGTATTCAACCACGCTTA
CCCTGTATCAACGGGATTGATCACCCGAAAGTACTTACCTATCTGGACGTCTTACGCGATAAAAAACCAGTCGGCCAACG
TGTGGCGATTATCGGTGCCGGTGGGATTGGTTTTGATACTGCGGAATATCTCAGCCAGTCTGGTGATAGTCCCCGTTTCG
ATAGCACAGCCTTCAGTACCGAATGGGGTATTGATCAAGATTTAGCTCATCGGGGGGGCCTATCACCCGCGGGGGCTAAA
GTCCCTCCATCCCCACGGCAGATTTTCCTGTTACAACGTAAAGCCAGCAAAGTCGGTGAAGGGCTGGGTAAAACCACCGG
TTGGATCCACCGCACCAGCTTGGCGATGCGCGGCGTCAAGATGCTTAACAGCGTCAGCTACGAGGCCATTGATGATAAAG
GGTTACATATCATTCGTGCGGAACAAGCCTGTTGTTTACCTGTCGATACCATTATTATTTGTGCCGGACAGGAGCCACGA
CGGGAGCTTCATCAGCCCTTACTGGATATGGGAAAAACAGTCTATTTGATTGGTGGTGCAGATAAGGCTGTTGAGCTGGA
TGCCCGCCGTGCCATTGATCAGGGTACCCGCCTAGCGCTAGCCATTTAG

Upstream 100 bases:

>100_bases
CGATTTCCCAACGGGCACACCACCGTCTAAATTTGAATAAAAAATCTCATCCGACCACTTGCTGGATTCAGTAAGGGCGG
CGGAGATATAACAATAATGG

Downstream 100 bases:

>100_bases
CCAAGAGAAGAATGGCGCGACCAGCAAGGTAAAGGGCCGTAACAAGGCCGAGAATAGCAATAGAACTGAGAATAATCACA
GGGTGTGGCGAAAACCCCAC

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MVVCLMETAMLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGGVYQ
GASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQL
AKQAGYDGVEIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVE
IEQLAQAVEQAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSM
ARPFLADAAFVQKAAQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFA
VTAARRGHQVTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRL
PCINGIDHPKVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAK
VPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPR
RELHQPLLDMGKTVYLIGGADKAVELDARRAIDQGTRLALAI

Sequences:

>Translated_682_residues
MVVCLMETAMLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGGVYQ
GASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQL
AKQAGYDGVEIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVE
IEQLAQAVEQAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSM
ARPFLADAAFVQKAAQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFA
VTAARRGHQVTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRL
PCINGIDHPKVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAK
VPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPR
RELHQPLLDMGKTVYLIGGADKAVELDARRAIDQGTRLALAI
>Mature_682_residues
MVVCLMETAMLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAGGVGLIVTGGIAPNMKGGVYQ
GASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSYQKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQL
AKQAGYDGVEIMGSEGYLINQFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVE
IEQLAQAVEQAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRINDPAVAEQVLADGCADMVSM
ARPFLADAAFVQKAAQGRADEINTCIGCNQACLDQIFDGKLTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFA
VTAARRGHQVTLFDAAAEIGGQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRL
PCINGIDHPKVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFSTEWGIDQDLAHRGGLSPAGAK
VPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVKMLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPR
RELHQPLLDMGKTVYLIGGADKAVELDARRAIDQGTRLALAI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=672, Percent_Identity=72.6190476190476, Blast_Score=1009, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=342, Percent_Identity=30.1169590643275, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17559804, Length=357, Percent_Identity=23.249299719888, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564188, Length=327, Percent_Identity=23.2415902140673, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17559802, Length=343, Percent_Identity=23.0320699708455, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565138, Length=239, Percent_Identity=24.6861924686192, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=214, Percent_Identity=29.9065420560748, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=220, Percent_Identity=23.1818181818182, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72001454, Length=179, Percent_Identity=27.3743016759777, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321973, Length=224, Percent_Identity=30.3571428571429, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73883; Mature: 73883

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVCLMETAMLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAG
CEEEEEHHHHHHCCCCCCCHHCCHHHHHHHHEECHHHHCHHHCCCCHHHHHHHHHHHHCC
GVGLIVTGGIAPNMKGGVYQGASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSY
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCC
QKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGVEIMGSEGYLIN
CCCCCCCHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHH
QFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVE
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEH
IEQLAQAVEQAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRI
HHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCC
NDPAVAEQVLADGCADMVSMARPFLADAAFVQKAAQGRADEINTCIGCNQACLDQIFDGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCC
LTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQVTLFDAAAEIG
HHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHC
GQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRL
CCEEEHHCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
PCINGIDHPKVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFST
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCC
EWGIDQDLAHRGGLSPAGAKVPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVK
CCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLDMGKTVYLIGGA
HHHHCCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECC
DKAVELDARRAIDQGTRLALAI
CCCEEHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MVVCLMETAMLAYPHLFTPLDLGFTTLKNRILMGSMHTGLEELPDGPQRLAAFYAERAAG
CEEEEEHHHHHHCCCCCCCHHCCHHHHHHHHEECHHHHCHHHCCCCHHHHHHHHHHHHCC
GVGLIVTGGIAPNMKGGVYQGASVLNDAAQIPHHQVVTEAVHQAGGKIALQILHAGRYSY
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCC
QKHPVAPSALQAPINPFVPQALSHEEILQTIADFAHCAQLAKQAGYDGVEIMGSEGYLIN
CCCCCCCHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHH
QFLTARTNQRDDEWGGDFTHRMRFAVEIVRAVRQATGHDFILIYRLSMLDLVEEGSNWVE
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEH
IEQLAQAVEQAGATVINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVNIPLITTNRI
HHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCC
NDPAVAEQVLADGCADMVSMARPFLADAAFVQKAAQGRADEINTCIGCNQACLDQIFDGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCC
LTSCLVNPRACRETEMPELPTDAPKRLAVVGAGPAGLAFAVTAARRGHQVTLFDAAAEIG
HHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHC
GQFNIAKQIPGKEEFYETLRYFRRQLVLNGVTLQLNTLVQVKQLAEFDEVILACGIQPRL
CCEEEHHCCCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
PCINGIDHPKVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQSGDSPRFDSTAFST
CCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCC
EWGIDQDLAHRGGLSPAGAKVPPSPRQIFLLQRKASKVGEGLGKTTGWIHRTSLAMRGVK
CCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
MLNSVSYEAIDDKGLHIIRAEQACCLPVDTIIICAGQEPRRELHQPLLDMGKTVYLIGGA
HHHHCCHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEECC
DKAVELDARRAIDQGTRLALAI
CCCEEHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]