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The map label for this gene is yqhD [H]

Identifier: 22127373

GI number: 22127373

Start: 3881761

End: 3882918

Strand: Direct

Name: yqhD [H]

Synonym: y3499

Alternate gene names: 22127373

Gene position: 3881761-3882918 (Clockwise)

Preceding gene: 22127371

Following gene: 22127375

Centisome position: 84.37

GC content: 51.38

Gene sequence:

>1158_bases
ATGCAAAATTTTACCCTTCATACCCCCACTAAAGTGCTGTTCGGTACCGGTCAAATCGCGCAATTGACTCAAGAAATCCC
GGCGGATGCCCGGATATTGATTACCTACGGCGGCGGCAGCATTAAACAAAATGGCGTGCTGGATCAAGTTCATCAAGCAT
TGAAAGGCTTTGATTTTCTGGAATTTGGTGGCATAGAACCCAATCCAACCTATGAAACGCTGATGAAAGCTGTCGAGCTA
TGCCGGACTGAAGGTATCAACTTCCTACTGGCCGTTGGCGGAGGGTCAGTATTGGATGGCACCAAATTTATTGCTGCAGC
GGTCAATTATCCACAAGATCCATGGCACATTCTGGAAACCACAGGGCGCGATATTACTGAAGCGCTGCCAATGGGCTCGG
TTCTGACCTTACCGGCAACAGGTTCTGAGGCTAATAATGGCGCAGTTATCAGCCGCCGTAGCACCGGAGATAAACAGCAC
TTCTTCTCACCCCATGTCCAGCCCCTGTTTGCCGTGCTGGATCCAGTGGTCACTTATACCTTGCCACCACGCCAGGTGGC
TAACGGTGTGGTCGATGCTTTTGTTCATACCATTGAGCAATATCTGACCTATCCCGTGGATGCCAAAGTACAGGATCGCT
TTGCTGAAGGGCTATTGTTGACCCTGATTGAAGAAGGCCCGAAAGCACTAAAAGATCCGGAAAACTACAATGTCCGCGCC
AATATTATGTGGAGCGCCACCATGGCCTTGAATGGCCTGATTGGTGCCGGTGTACCACAGGATTGGGCCACCCATATGTT
GGGCCACGAACTGACTGCGCGCCATGGTTTGGATCATGCACAAACATTGGCGGTAGTGTTACCGGCCCTGCTGGTTGCGA
AGAAGCAGCAAAAGCGCGCCAAACTGCTGCAATATGCAGAGCGTGTCTGGGGATTGCGTGAGGGCAGTGAAGATCAGCGC
ATTGATGCGGCGATTGAAGCCACCCGTCACTTCTTCGAAAGCCTGGGTGTAGCGACTCGCTTATCCGCCTACAAACTGGA
CGGCAGTTCTATTCCGGATCTGATTAAAAAGCTGGAAGAGCACGGGATGACCAAACTGGGTGAGCACAGTGACATCACCT
TAGCTGACAGCAAGCGTATCTATGAAGCGGCGGTATAA

Upstream 100 bases:

>100_bases
ACAGTGATGTGGTTACGGATAAATACTCACTGCATCACCTTATCGCTAAGCAGCAACACCTGTTTTTTTACTGTTCATCC
CATAAGCTGGAAGAGAAATC

Downstream 100 bases:

>100_bases
CCGTTTTATGTAAGATTTAACGGGATTTAGCCTGCATTTATCTCGTACCAAAACTGGCGGCATTACCGCATGTCATGCTG
CCAGTCCTCCTGTTTATACC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQNFTLHTPTKVLFGTGQIAQLTQEIPADARILITYGGGSIKQNGVLDQVHQALKGFDFLEFGGIEPNPTYETLMKAVEL
CRTEGINFLLAVGGGSVLDGTKFIAAAVNYPQDPWHILETTGRDITEALPMGSVLTLPATGSEANNGAVISRRSTGDKQH
FFSPHVQPLFAVLDPVVTYTLPPRQVANGVVDAFVHTIEQYLTYPVDAKVQDRFAEGLLLTLIEEGPKALKDPENYNVRA
NIMWSATMALNGLIGAGVPQDWATHMLGHELTARHGLDHAQTLAVVLPALLVAKKQQKRAKLLQYAERVWGLREGSEDQR
IDAAIEATRHFFESLGVATRLSAYKLDGSSIPDLIKKLEEHGMTKLGEHSDITLADSKRIYEAAV

Sequences:

>Translated_385_residues
MQNFTLHTPTKVLFGTGQIAQLTQEIPADARILITYGGGSIKQNGVLDQVHQALKGFDFLEFGGIEPNPTYETLMKAVEL
CRTEGINFLLAVGGGSVLDGTKFIAAAVNYPQDPWHILETTGRDITEALPMGSVLTLPATGSEANNGAVISRRSTGDKQH
FFSPHVQPLFAVLDPVVTYTLPPRQVANGVVDAFVHTIEQYLTYPVDAKVQDRFAEGLLLTLIEEGPKALKDPENYNVRA
NIMWSATMALNGLIGAGVPQDWATHMLGHELTARHGLDHAQTLAVVLPALLVAKKQQKRAKLLQYAERVWGLREGSEDQR
IDAAIEATRHFFESLGVATRLSAYKLDGSSIPDLIKKLEEHGMTKLGEHSDITLADSKRIYEAAV
>Mature_385_residues
MQNFTLHTPTKVLFGTGQIAQLTQEIPADARILITYGGGSIKQNGVLDQVHQALKGFDFLEFGGIEPNPTYETLMKAVEL
CRTEGINFLLAVGGGSVLDGTKFIAAAVNYPQDPWHILETTGRDITEALPMGSVLTLPATGSEANNGAVISRRSTGDKQH
FFSPHVQPLFAVLDPVVTYTLPPRQVANGVVDAFVHTIEQYLTYPVDAKVQDRFAEGLLLTLIEEGPKALKDPENYNVRA
NIMWSATMALNGLIGAGVPQDWATHMLGHELTARHGLDHAQTLAVVLPALLVAKKQQKRAKLLQYAERVWGLREGSEDQR
IDAAIEATRHFFESLGVATRLSAYKLDGSSIPDLIKKLEEHGMTKLGEHSDITLADSKRIYEAAV

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=354, Percent_Identity=22.8813559322034, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789386, Length=386, Percent_Identity=77.2020725388601, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI87082107, Length=340, Percent_Identity=25, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994951, Length=299, Percent_Identity=25.4180602006689, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=25.8485639686684, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787493, Length=368, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42041; Mature: 42041

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNFTLHTPTKVLFGTGQIAQLTQEIPADARILITYGGGSIKQNGVLDQVHQALKGFDFL
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCH
EFGGIEPNPTYETLMKAVELCRTEGINFLLAVGGGSVLDGTKFIAAAVNYPQDPWHILET
HCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHH
TGRDITEALPMGSVLTLPATGSEANNGAVISRRSTGDKQHFFSPHVQPLFAVLDPVVTYT
CCCHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCC
LPPRQVANGVVDAFVHTIEQYLTYPVDAKVQDRFAEGLLLTLIEEGPKALKDPENYNVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEE
NIMWSATMALNGLIGAGVPQDWATHMLGHELTARHGLDHAQTLAVVLPALLVAKKQQKRA
EEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KLLQYAERVWGLREGSEDQRIDAAIEATRHFFESLGVATRLSAYKLDGSSIPDLIKKLEE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHEECCCCCHHHHHHHHHH
HGMTKLGEHSDITLADSKRIYEAAV
CCCCCCCCCCCEEEECCCHHHHHCC
>Mature Secondary Structure
MQNFTLHTPTKVLFGTGQIAQLTQEIPADARILITYGGGSIKQNGVLDQVHQALKGFDFL
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCH
EFGGIEPNPTYETLMKAVELCRTEGINFLLAVGGGSVLDGTKFIAAAVNYPQDPWHILET
HCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCHHHHHH
TGRDITEALPMGSVLTLPATGSEANNGAVISRRSTGDKQHFFSPHVQPLFAVLDPVVTYT
CCCHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCC
LPPRQVANGVVDAFVHTIEQYLTYPVDAKVQDRFAEGLLLTLIEEGPKALKDPENYNVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEE
NIMWSATMALNGLIGAGVPQDWATHMLGHELTARHGLDHAQTLAVVLPALLVAKKQQKRA
EEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KLLQYAERVWGLREGSEDQRIDAAIEATRHFFESLGVATRLSAYKLDGSSIPDLIKKLEE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHEECCCCCHHHHHHHHHH
HGMTKLGEHSDITLADSKRIYEAAV
CCCCCCCCCCCEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]