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The map label for this gene is gpo [H]

Identifier: 21909964

GI number: 21909964

Start: 467209

End: 467688

Strand: Reverse

Name: gpo [H]

Synonym: SpyM3_0428

Alternate gene names: 21909964

Gene position: 467688-467209 (Counterclockwise)

Preceding gene: 21909965

Following gene: 21909961

Centisome position: 24.61

GC content: 39.58

Gene sequence:

>480_bases
ATGCCTAATCTCTATGATTTTACGGTTAAGGCTCAGGACGGCAGTGACATCTCACTAGTTAACTACAAAGAAAAAGTGGT
TTTGGTCGTGAATACAGCTACCAAATGTGGACTAACCCCACAATACCAGGCCTTGCAAGCGCTATATGACACATACCATG
ACAAGGGATTTGAGGTCTTAGATTTTCCTTGCAACCAATTTCTAAATCAAACTCCAGGGGAAGCCGAAGAGATTAATCGA
TTTTGCAGCTTAACCTATCACACTACTTTCCCTCGCTTTGCAAAAATCAAAGTAAATGGTAAAGACGCTGATCCTTTGTT
CACCTGGTTAAAAGAAGAAAAAAGTGGTCCCCTTGGGAAACGCATCGAATGGAATTTCACTAAATTTCTCATTGACCAAA
ATGGTCAAGTCATTAAACGCTATTCCTCAAAGACAGATCCTAAACTAATTGAAGAAGACCTTAAAGCACTTCTTGGTTAA

Upstream 100 bases:

>100_bases
ATTGGGGCAGACATTGCTACTGAAAAACCTCTTCGAGATACCATTCAATTCTTGAGTGAGACCGTTGACCAAATTATCAG
TTACACCGAGGATATGTCAC

Downstream 100 bases:

>100_bases
TATAAAATAGACTTGGCGTGCCAAGTCTATTTTATATTATAGTTACTATTTAAAAACTTCTTGATAAAATTCAATGCTAT
CACCATCTTTAACGGTAATT

Product: putative glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQALQALYDTYHDKGFEVLDFPCNQFLNQTPGEAEEINR
FCSLTYHTTFPRFAKIKVNGKDADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG

Sequences:

>Translated_159_residues
MPNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQALQALYDTYHDKGFEVLDFPCNQFLNQTPGEAEEINR
FCSLTYHTTFPRFAKIKVNGKDADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG
>Mature_158_residues
PNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQALQALYDTYHDKGFEVLDFPCNQFLNQTPGEAEEINRF
CSLTYHTTFPRFAKIKVNGKDADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=44.5161290322581, Blast_Score=129, Evalue=9e-31,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=44.5161290322581, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI192455698, Length=157, Percent_Identity=38.2165605095541, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=38.2165605095541, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=42.3076923076923, Blast_Score=100, Evalue=4e-22,
Organism=Homo sapiens, GI4557629, Length=179, Percent_Identity=34.0782122905028, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=32.0652173913043, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI6006001, Length=178, Percent_Identity=33.1460674157303, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=30.2702702702703, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI33186887, Length=172, Percent_Identity=30.8139534883721, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788003, Length=174, Percent_Identity=39.6551724137931, Blast_Score=131, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=46.875, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=44.0251572327044, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=156, Percent_Identity=41.6666666666667, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=160, Percent_Identity=41.25, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.3558282208589, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.1288343558282, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=37.8947368421053, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=46.4788732394366, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=104, Percent_Identity=38.4615384615385, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=49.6815286624204, Blast_Score=167, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=49.685534591195, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=42.7672955974843, Blast_Score=135, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=47.1698113207547, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=47.1698113207547, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=47.1698113207547, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=37.9746835443038, Blast_Score=112, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18207; Mature: 18076

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQALQALYDTYHDKGFEVL
CCCCEEEEEEECCCCCEEEEEECCEEEEEEECCHHCCCCHHHHHHHHHHHHHCCCCCEEE
DFPCNQFLNQTPGEAEEINRFCSLTYHTTFPRFAKIKVNGKDADPLFTWLKEEKSGPLGK
ECCHHHHHHCCCCCHHHHHHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCC
RIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG
EEECCCEEEEECCCCCEEEHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQALQALYDTYHDKGFEVL
CCCEEEEEEECCCCCEEEEEECCEEEEEEECCHHCCCCHHHHHHHHHHHHHCCCCCEEE
DFPCNQFLNQTPGEAEEINRFCSLTYHTTFPRFAKIKVNGKDADPLFTWLKEEKSGPLGK
ECCHHHHHHCCCCCHHHHHHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCC
RIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG
EEECCCEEEEECCCCCEEEHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]