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The map label for this gene is fabI

Identifier: 21672535

GI number: 21672535

Start: 291293

End: 292075

Strand: Direct

Name: fabI

Synonym: BUsg255

Alternate gene names: 21672535

Gene position: 291293-292075 (Clockwise)

Preceding gene: 21672534

Following gene: 21672536

Centisome position: 45.41

GC content: 23.63

Gene sequence:

>783_bases
ATGGGAATTTTAAAAGGTAAAAAAATTTTAATTACTGGTATCTTAAATGAAAAATCAATTGCATTTGGTATTGCAAAATC
AATGTATAAACAAGAAGCAGAATTAATTTTTGTGTGTCAAAACAAAAAAATAATTAATAAAATAAAATATTTAATTAAAT
CAATTAATTACAATACTATTTTCTTTTGTGATGTATCTCACGATGAAAATATTAAAGAACTATTTTTTAATATAAAAAAA
GTTTGGAATAATTTTGATGGATTAGTTCATTCTATTGCTTATTGTCCTAAAAAGCAAATGCATGAAGATTTCGTTGAAAG
CAGCAGTAGAAAATCATTCAATATATGTCATGAAATTAGTTCATATAGTTTTTTAAGTATGGCGAGAGAATGTAAAAATA
TGCTGAATAAATTTTCCTCTCTAGTAACATTATCTTATCTAGGTTCACAAAAAATAGTATCTAATTATAATATGATGGGT
TTAGCAAAATCTTCTTTAGAAGCTAATGTTCGTTACATGGCTAATTCACTTGGTAAAAATAATATTAGAGTGAATGCTAT
TTCTTCTGGACCTATTAAAACTACATCTTCTTATCAAATTAAAAACTTTAACAAAATACAAAAAATACATAAGTTATTTT
CATTAACAAAAAATCATGTATCCAGTGAAGAAATAGGAAATGTTGCAGCCTTTTTATGTTCGGATTTATCTATTGGAATT
ACTGGTTCAATTATTAATGTTGATCACGGTTTTAATTTAAATGGAATAAATTCTATAATTTAA

Upstream 100 bases:

>100_bases
GTCATAAAAATTTATAATGTAATTTAAATATTTTTTGTCATTTTTGAGTGTAAAATATAAAATATTTTTTATATATCAAG
TATATATTTGGAATTTTAAA

Downstream 100 bases:

>100_bases
ATTCATGTAAATAAAATTTTTTAAATATGTTTTTTTCAGTTACTAATCTGAAATTTAACTTTAAAGTAATTTGATAAATA
TAATATTAATTTTCATTAAA

Product: enoyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTIFFCDVSHDENIKELFFNIKK
VWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEISSYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMG
LAKSSLEANVRYMANSLGKNNIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGI
TGSIINVDHGFNLNGINSII

Sequences:

>Translated_260_residues
MGILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTIFFCDVSHDENIKELFFNIKK
VWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEISSYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMG
LAKSSLEANVRYMANSLGKNNIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGI
TGSIINVDHGFNLNGINSII
>Mature_259_residues
GILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTIFFCDVSHDENIKELFFNIKKV
WNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEISSYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMGL
AKSSLEANVRYMANSLGKNNIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGIT
GSIINVDHGFNLNGINSII

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily

Homologues:

Organism=Escherichia coli, GI1787545, Length=259, Percent_Identity=47.1042471042471, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): FABI_BUCAP (Q8K9Q6)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660602.1
- ProteinModelPortal:   Q8K9Q6
- SMR:   Q8K9Q6
- EnsemblBacteria:   EBBUCT00000000510
- GeneID:   1005457
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg255
- GeneTree:   EBGT00050000007854
- HOGENOM:   HBG750976
- OMA:   LVHCLAF
- ProtClustDB:   CLSK315843
- BioCyc:   BAPH198804:BUSG255-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PANTHER:   PTHR19410:SF12
- PIRSF:   PIRSF000094

Pfam domain/function: NA

EC number: =1.3.1.9

Molecular weight: Translated: 29268; Mature: 29137

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00290 IG_MHC

Important sites: ACT_SITE 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTI
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEE
FFCDVSHDENIKELFFNIKKVWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEIS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
SYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMGLAKSSLEANVRYMANSLGKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
NIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGI
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCE
TGSIINVDHGFNLNGINSII
EEEEEEECCCCCCCCHHHCC
>Mature Secondary Structure 
GILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTI
CCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEE
FFCDVSHDENIKELFFNIKKVWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEIS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
SYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMGLAKSSLEANVRYMANSLGKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
NIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGI
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCE
TGSIINVDHGFNLNGINSII
EEEEEEECCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438