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The map label for this gene is yfhC [C]

Identifier: 21672527

GI number: 21672527

Start: 282303

End: 282758

Strand: Direct

Name: yfhC [C]

Synonym: BUsg246

Alternate gene names: 21672527

Gene position: 282303-282758 (Clockwise)

Preceding gene: 21672526

Following gene: 21672533

Centisome position: 44.01

GC content: 25.44

Gene sequence:

>456_bases
ATGAAAAGTAATCGCGATAGCTATTGGATGAAAATTGCTTTAAAATATGCATATTATGCAGAAGAAAATGGAGAGGTACC
TATAGGTGCAATACTTGTTTTTCAAGAAAAAATAATAGGAACGGGATGGAATAGTGTTATTTCTCAAAATGATTCTACTG
CTCACGCAGAAATTATAGCTTTACGTGAAGCAGGTAGAAACATAAAAAATTATAGATTAGTAAATACAACGTTATATGTC
ACATTACAACCATGTATGATGTGTTGTGGAGCTATTATAAATAGTCGTATTAAAAGATTAGTATTTGGTGCAAGTTATAA
AGATTTAAAAAAAAACCCCTTTTTAAAAAAAATTTTTATAAATCTAGAAAAAAATAAATTAAAAATAAAAAAACACATAA
TGAGAAATGAATGTGCTAAGATATTAAGCAATTTTTTTAAAAATAAAAGATTTTAA

Upstream 100 bases:

>100_bases
AACTAAAATAGATAAAAGAGCGAGTGAAAAACAAAACGAATGGAAAAAAGAAAAATTAAAAATTTTAAAGAAAGTTAAAT
TTCAGAATTAAAAATATTTT

Downstream 100 bases:

>100_bases
TTTATACCCTTTTTCTTAAAAATAATTATTTTTCTAAAATAACTAATGCACATGCGTACAATTTCTCATCAGATATACTG
ACAAATATAGATTTACATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKSNRDSYWMKIALKYAYYAEENGEVPIGAILVFQEKIIGTGWNSVISQNDSTAHAEIIALREAGRNIKNYRLVNTTLYV
TLQPCMMCCGAIINSRIKRLVFGASYKDLKKNPFLKKIFINLEKNKLKIKKHIMRNECAKILSNFFKNKRF

Sequences:

>Translated_151_residues
MKSNRDSYWMKIALKYAYYAEENGEVPIGAILVFQEKIIGTGWNSVISQNDSTAHAEIIALREAGRNIKNYRLVNTTLYV
TLQPCMMCCGAIINSRIKRLVFGASYKDLKKNPFLKKIFINLEKNKLKIKKHIMRNECAKILSNFFKNKRF
>Mature_151_residues
MKSNRDSYWMKIALKYAYYAEENGEVPIGAILVFQEKIIGTGWNSVISQNDSTAHAEIIALREAGRNIKNYRLVNTTLYV
TLQPCMMCCGAIINSRIKRLVFGASYKDLKKNPFLKKIFINLEKNKLKIKKHIMRNECAKILSNFFKNKRF

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Homo sapiens, GI124107608, Length=102, Percent_Identity=35.2941176470588, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=47.2222222222222, Blast_Score=147, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17554608, Length=101, Percent_Identity=39.6039603960396, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=106, Percent_Identity=35.8490566037736, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=105, Percent_Identity=39.0476190476191, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=151, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y246_BUCAP (Q8K9R4)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660594.1
- ProteinModelPortal:   Q8K9R4
- SMR:   Q8K9R4
- EnsemblBacteria:   EBBUCT00000000308
- GeneID:   1005448
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg246
- GeneTree:   EBGT00050000007901
- HOGENOM:   HBG741046
- OMA:   DMGACGS
- ProtClustDB:   CLSK493053
- BioCyc:   BAPH198804:BUSG246-MONOMER
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193

Pfam domain/function: PF00383 dCMP_cyt_deam_1; SSF53927 Cytidine_deaminase-like

EC number: NA

Molecular weight: Translated: 17502; Mature: 17502

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNRDSYWMKIALKYAYYAEENGEVPIGAILVFQEKIIGTGWNSVISQNDSTAHAEIIA
CCCCCCCCEEHEEEHHHEEECCCCCCCCHHHEEEHHHHHCCCHHHHHCCCCCCHHHHHHH
LREAGRNIKNYRLVNTTLYVTLQPCMMCCGAIINSRIKRLVFGASYKDLKKNPFLKKIFI
HHHHCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHEE
NLEKNKLKIKKHIMRNECAKILSNFFKNKRF
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSNRDSYWMKIALKYAYYAEENGEVPIGAILVFQEKIIGTGWNSVISQNDSTAHAEIIA
CCCCCCCCEEHEEEHHHEEECCCCCCCCHHHEEEHHHHHCCCHHHHHCCCCCCHHHHHHH
LREAGRNIKNYRLVNTTLYVTLQPCMMCCGAIINSRIKRLVFGASYKDLKKNPFLKKIFI
HHHHCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHEE
NLEKNKLKIKKHIMRNECAKILSNFFKNKRF
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438