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The map label for this gene is dnaQ [H]

Identifier: 21672521

GI number: 21672521

Start: 278600

End: 279304

Strand: Direct

Name: dnaQ [H]

Synonym: BUsg240

Alternate gene names: 21672521

Gene position: 278600-279304 (Clockwise)

Preceding gene: 161485725

Following gene: 21672522

Centisome position: 43.43

GC content: 21.42

Gene sequence:

>705_bases
ATGATGAATAATACACAAAGAATAATTGTTTTAGATACTGAAACAACAGGAATGAATAGTGTAGGTCCACCTTATCTTAA
TCATAGAATTATTGAAATTGGTGCCATTGAAATAATTAATCGTCGTTTTACAGGGAAAAAATTTCATACTTATATTAAAC
CTAATAGATTGATAGAATCTGACGCTTCAAAAATTCATGGTATTACTGATGATTTTTTATCAGATAAACCATCTTTTAAA
GACATAGCTAAAGATTTTTTTAATTATATAAAAAATTCAGAATTAATAATTCATAATGCATCTTTTGATGTAGGTTTCAT
AAATCAAGAATTTTCAATGTTAACTAAAAAAATACAAGATATATCAAATTTTTGTAATATTATAGATACATTAAAGATAG
CTAGAAAATTATTTCCTGGTAAAAAAAATACCTTAGACGCATTATGTATGCGTTATAAAATAAAAAATTCTCATAGAGTT
TTACATGGTGCTATTTTAGATGCTTTTCTATTAGGTAAATTATATCTTTTAATGACTAGTGGTCAAGAATCAATTATATT
TAATAAAAATATCCAAAATGAAAGAAATTTTAGATATATTAAAAAATCAATAACAAAAAAACATCGTTTTTTAAAAATAA
TAAAAGCAAATAAAACAGAATTAAAACTTCATAATGAATATTTAAAATTTTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
TGATCCAGGATTTCCTAAACAAGAACCATCTGAAAACATTTTAACTAATTTTAACATTTTAATAATTATTCCAATATTAA
ATAACTTAAATAGATCATTT

Downstream 100 bases:

>100_bases
TGTCTATTTCGTAGTAAATTATGAATAACTATAAAAAGATGATTGACTCATTTTTTTAAAATATGTACAATGTATAAATA
TTAATAATAAAGGTGCGGTA

Product: DNA polymerase III epsilon chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MMNNTQRIIVLDTETTGMNSVGPPYLNHRIIEIGAIEIINRRFTGKKFHTYIKPNRLIESDASKIHGITDDFLSDKPSFK
DIAKDFFNYIKNSELIIHNASFDVGFINQEFSMLTKKIQDISNFCNIIDTLKIARKLFPGKKNTLDALCMRYKIKNSHRV
LHGAILDAFLLGKLYLLMTSGQESIIFNKNIQNERNFRYIKKSITKKHRFLKIIKANKTELKLHNEYLKFLKEK

Sequences:

>Translated_234_residues
MMNNTQRIIVLDTETTGMNSVGPPYLNHRIIEIGAIEIINRRFTGKKFHTYIKPNRLIESDASKIHGITDDFLSDKPSFK
DIAKDFFNYIKNSELIIHNASFDVGFINQEFSMLTKKIQDISNFCNIIDTLKIARKLFPGKKNTLDALCMRYKIKNSHRV
LHGAILDAFLLGKLYLLMTSGQESIIFNKNIQNERNFRYIKKSITKKHRFLKIIKANKTELKLHNEYLKFLKEK
>Mature_234_residues
MMNNTQRIIVLDTETTGMNSVGPPYLNHRIIEIGAIEIINRRFTGKKFHTYIKPNRLIESDASKIHGITDDFLSDKPSFK
DIAKDFFNYIKNSELIIHNASFDVGFINQEFSMLTKKIQDISNFCNIIDTLKIARKLFPGKKNTLDALCMRYKIKNSHRV
LHGAILDAFLLGKLYLLMTSGQESIIFNKNIQNERNFRYIKKSITKKHRFLKIIKANKTELKLHNEYLKFLKEK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=236, Percent_Identity=47.8813559322034, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI1788149, Length=182, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 27301; Mature: 27301

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNTQRIIVLDTETTGMNSVGPPYLNHRIIEIGAIEIINRRFTGKKFHTYIKPNRLIES
CCCCCCEEEEEECCCCCCCCCCCCHHCCEEEEEHHHHHHHHHCCCCHHHEEECCCHHHHH
DASKIHGITDDFLSDKPSFKDIAKDFFNYIKNSELIIHNASFDVGFINQEFSMLTKKIQD
HHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHH
ISNFCNIIDTLKIARKLFPGKKNTLDALCMRYKIKNSHRVLHGAILDAFLLGKLYLLMTS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEC
GQESIIFNKNIQNERNFRYIKKSITKKHRFLKIIKANKTELKLHNEYLKFLKEK
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMNNTQRIIVLDTETTGMNSVGPPYLNHRIIEIGAIEIINRRFTGKKFHTYIKPNRLIES
CCCCCCEEEEEECCCCCCCCCCCCHHCCEEEEEHHHHHHHHHCCCCHHHEEECCCHHHHH
DASKIHGITDDFLSDKPSFKDIAKDFFNYIKNSELIIHNASFDVGFINQEFSMLTKKIQD
HHHHHCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEECCHHHHHHHHHHHH
ISNFCNIIDTLKIARKLFPGKKNTLDALCMRYKIKNSHRVLHGAILDAFLLGKLYLLMTS
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEC
GQESIIFNKNIQNERNFRYIKKSITKKHRFLKIIKANKTELKLHNEYLKFLKEK
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9000520; 12089438; 7507875 [H]