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The map label for this gene is nuoA

Identifier: 21672437

GI number: 21672437

Start: 165160

End: 165540

Strand: Direct

Name: nuoA

Synonym: BUsg147

Alternate gene names: 21672437

Gene position: 165160-165540 (Clockwise)

Preceding gene: 21672434

Following gene: 21672438

Centisome position: 25.75

GC content: 27.03

Gene sequence:

>381_bases
ATGCTGAAAAATACATTAGATATGACTGAATATTTATCTTTTCTTTACTTTATTTTTTTTTCTTTATTTTTTTGTTGTTT
TATGCTATTTACAAGTTGGTTTTTAGGGGGAAGATCGTTATCAAGATATAAAAATACTCCTTTTGAATCTGGCGTTGTTT
CAGTAGGTAATACACATCTTCATTTTTCTGTAAAATTTTATTTAATTGCAATTTTTTTTGTAATTTTTGATGTTGAAGCA
CTTTATCTATATGCATGGTCTGTTAGTATAGTTGAATCAGGGTGGATCGGTTTTGTTGAAGCCACTATATTTATACTTTT
TCTTCTTTTATCATTGTTTTATTTAGTCCGAATTAAAGCTTTAAACTGGGTTACGTCATGA

Upstream 100 bases:

>100_bases
ACAAATTGCATTTTTTTATTGATTTTTACTAAGATACAATAGATAGTTTGATTATCATAGTTATAAAAATATTTTTATAT
TTTATTAGGAACTATAAATA

Downstream 100 bases:

>100_bases
TAATATCAAAAAAATTGACATTGATTATATTTAGGATTTAATTAGATGAAAGAAAAAATGAATTATACTTTAACTAGAGC
AGAAAGAAAAAGTCAGAGAC

Product: NADH dehydrogenase I chain A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MLKNTLDMTEYLSFLYFIFFSLFFCCFMLFTSWFLGGRSLSRYKNTPFESGVVSVGNTHLHFSVKFYLIAIFFVIFDVEA
LYLYAWSVSIVESGWIGFVEATIFILFLLLSLFYLVRIKALNWVTS

Sequences:

>Translated_126_residues
MLKNTLDMTEYLSFLYFIFFSLFFCCFMLFTSWFLGGRSLSRYKNTPFESGVVSVGNTHLHFSVKFYLIAIFFVIFDVEA
LYLYAWSVSIVESGWIGFVEATIFILFLLLSLFYLVRIKALNWVTS
>Mature_126_residues
MLKNTLDMTEYLSFLYFIFFSLFFCCFMLFTSWFLGGRSLSRYKNTPFESGVVSVGNTHLHFSVKFYLIAIFFVIFDVEA
LYLYAWSVSIVESGWIGFVEATIFILFLLLSLFYLVRIKALNWVTS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=126, Percent_Identity=57.1428571428571, Blast_Score=150, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_BUCAP (Q8K9Y7)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660504.1
- EnsemblBacteria:   EBBUCT00000000003
- GeneID:   1005964
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg147
- GeneTree:   EBGT00050000008167
- HOGENOM:   HBG605540
- ProtClustDB:   CLSK315571
- BioCyc:   BAPH198804:BUSG147-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 14783; Mature: 14783

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x9673374)-; HASH(0xc0ae60c)-; HASH(0xbf9d470)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKNTLDMTEYLSFLYFIFFSLFFCCFMLFTSWFLGGRSLSRYKNTPFESGVVSVGNTHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEECCCCEE
HFSVKFYLIAIFFVIFDVEALYLYAWSVSIVESGWIGFVEATIFILFLLLSLFYLVRIKA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNWVTS
HHHCCH
>Mature Secondary Structure
MLKNTLDMTEYLSFLYFIFFSLFFCCFMLFTSWFLGGRSLSRYKNTPFESGVVSVGNTHL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEECCCCEE
HFSVKFYLIAIFFVIFDVEALYLYAWSVSIVESGWIGFVEATIFILFLLLSLFYLVRIKA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNWVTS
HHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438