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The map label for this gene is argB

Identifier: 21672339

GI number: 21672339

Start: 53489

End: 54265

Strand: Direct

Name: argB

Synonym: BUsg046

Alternate gene names: 21672339

Gene position: 53489-54265 (Clockwise)

Preceding gene: 21672338

Following gene: 21672340

Centisome position: 8.34

GC content: 30.76

Gene sequence:

>777_bases
ATGATGAGTCCTTTGGTTATTAAATTAGGTGGAGTTCTTTTAGAAAGTGATAATGCAATGATGCGTTTGTTTAAAGCGCT
TCTTGATTATCAAAAATCTAATAAACGACATATTTTAATAATTCATGGAGGAGGACGCTTAATAGATGATTTAATGAATA
AATTATCATTGCCTATTGAGAAAAAAAATGGTTTGCGAATCACTCAATCTGAACATATTAATGTTATTACAGGTGCGTTA
GCAGGAACAGCTAACAAAATTCTGCTTTCATGGGCATTAAAATATAAAATAAATGCTGTTGGTTTGTGTTTAGCAGATGG
AAAAAGTGTTAATGTAGAAAAATTAGATCAGGATTTAGGGCACGTTGGAAAAGCTAAACCAGGTTCTCCTCTTTTTTTAA
CAAAATTATGCGAACAAGGCATTTTACCAATCATTAGTTCTATAGGTATTACAGATGATGGTTTATTAATGAATGTTAAT
GCAGATTTAGCAGCCACGGCTTTGGCTACTACCTTAAAAGCAAATTTGATTTTATTATCTGATATAAGTTCAATATTAGA
TGGTAAAGGTCAAAGAATTTCAGAAATAAATTACCTTCAAGCTAAAAAATTAATATCTCAGGGTATTATTACTAATGGTA
TGATCGTTAAGGTGAATGCAGCTTTAGAAGCAGCTCGGGTATTACAACGTTCTATAGATATTGCTAGTTGGCAAAATACA
GATCAACTTAAATTATTATTTAATGGTATCAATATTGGTACTCGAGTTTTAGTATAG

Upstream 100 bases:

>100_bases
TAATTTATTGAAAGGTGCAGCTGCACAAGCTATACAATGTTTTAATATTCGTTTTGGATTTTCTGAAATTGAATCAATTA
TTTAAATGAGGTATTTTTTG

Downstream 100 bases:

>100_bases
TCTGATTATAATAGGTTGTAAAAATATTATGAATAATTTTAAAAAAGTGGTGTTAGCATATTCTGGTGGTTTAGATACTT
CAGCCATCATCCCTTGGTTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMSPLVIKLGGVLLESDNAMMRLFKALLDYQKSNKRHILIIHGGGRLIDDLMNKLSLPIEKKNGLRITQSEHINVITGAL
AGTANKILLSWALKYKINAVGLCLADGKSVNVEKLDQDLGHVGKAKPGSPLFLTKLCEQGILPIISSIGITDDGLLMNVN
ADLAATALATTLKANLILLSDISSILDGKGQRISEINYLQAKKLISQGIITNGMIVKVNAALEAARVLQRSIDIASWQNT
DQLKLLFNGINIGTRVLV

Sequences:

>Translated_258_residues
MMSPLVIKLGGVLLESDNAMMRLFKALLDYQKSNKRHILIIHGGGRLIDDLMNKLSLPIEKKNGLRITQSEHINVITGAL
AGTANKILLSWALKYKINAVGLCLADGKSVNVEKLDQDLGHVGKAKPGSPLFLTKLCEQGILPIISSIGITDDGLLMNVN
ADLAATALATTLKANLILLSDISSILDGKGQRISEINYLQAKKLISQGIITNGMIVKVNAALEAARVLQRSIDIASWQNT
DQLKLLFNGINIGTRVLV
>Mature_258_residues
MMSPLVIKLGGVLLESDNAMMRLFKALLDYQKSNKRHILIIHGGGRLIDDLMNKLSLPIEKKNGLRITQSEHINVITGAL
AGTANKILLSWALKYKINAVGLCLADGKSVNVEKLDQDLGHVGKAKPGSPLFLTKLCEQGILPIISSIGITDDGLLMNVN
ADLAATALATTLKANLILLSDISSILDGKGQRISEINYLQAKKLISQGIITNGMIVKVNAALEAARVLQRSIDIASWQNT
DQLKLLFNGINIGTRVLV

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=257, Percent_Identity=63.4241245136187, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_BUCAP (P59098)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660406.1
- ProteinModelPortal:   P59098
- SMR:   P59098
- EnsemblBacteria:   EBBUCT00000000538
- GeneID:   1005862
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg046
- GeneTree:   EBGT00050000008092
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   BAPH198804:BUSG046-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27821; Mature: 27821

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: BINDING 66-66 BINDING 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPLVIKLGGVLLESDNAMMRLFKALLDYQKSNKRHILIIHGGGRLIDDLMNKLSLPIE
CCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEE
KKNGLRITQSEHINVITGALAGTANKILLSWALKYKINAVGLCLADGKSVNVEKLDQDLG
CCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHH
HVGKAKPGSPLFLTKLCEQGILPIISSIGITDDGLLMNVNADLAATALATTLKANLILLS
HCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCEEEEE
DISSILDGKGQRISEINYLQAKKLISQGIITNGMIVKVNAALEAARVLQRSIDIASWQNT
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCHHCCCCC
DQLKLLFNGINIGTRVLV
CEEEEEEECCCCCEEEEC
>Mature Secondary Structure
MMSPLVIKLGGVLLESDNAMMRLFKALLDYQKSNKRHILIIHGGGRLIDDLMNKLSLPIE
CCCCEEEEECCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEE
KKNGLRITQSEHINVITGALAGTANKILLSWALKYKINAVGLCLADGKSVNVEKLDQDLG
CCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHEEEEEEEEEEEECCCCCCHHHHHHHHH
HVGKAKPGSPLFLTKLCEQGILPIISSIGITDDGLLMNVNADLAATALATTLKANLILLS
HCCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCEEEEE
DISSILDGKGQRISEINYLQAKKLISQGIITNGMIVKVNAALEAARVLQRSIDIASWQNT
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCHHCCCCC
DQLKLLFNGINIGTRVLV
CEEEEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438