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The map label for this gene is murG

Identifier: 30263912

GI number: 30263912

Start: 3728239

End: 3729333

Strand: Reverse

Name: murG

Synonym: BA_4049

Alternate gene names: 30263912

Gene position: 3729333-3728239 (Counterclockwise)

Preceding gene: 30263913

Following gene: 30263911

Centisome position: 71.34

GC content: 36.99

Gene sequence:

>1095_bases
GTGCGTGTATTAGTAAGTGGTGGGGGCACTGGAGGTCATATTTATCCGGCTCTTGCTTTAATAAGAGAAATAAAAAAATT
AAATCCGGAAGCAAGGTTTTTATATATTGGTACGGAAAATGGATTAGAGAGTACAATCGTTCCAAAAGCAGGTATACCGT
TTCAATCTATTGTTATAAGTGGATTTAAGCGTAAAATATCGTTAGATAACGTGAAAACGGTGATGCGTTTCCTAAAAGGT
GTACAAGACAGTAAGCGATATATTCGTCGTTTCAATCCAGATATTGTAATTGGAACGGGTGGATATGTATGTGGACCTGT
TGTATATGCTGCGGCAAAATTAGGTATTCCAACGATTGTACATGAACAAAATAGTGTACCTGGTGTAACGAATAAATTTT
TAAGCCGCTATGTTGATAAAGTTGCAGTTTGTTTTGAAGCGGCTGCAGAACATTTTCCACAGTCAAAAGTGGTCATGACA
GGAAATCCACGAGCGTCAGAAGTAATGGATCAAAATGGAATGAAAGGAAAACGTTCAGTAGGTTTATCCCTTCCTAAAAA
ATCCGTGCTTATTTTTGGTGGAAGCCGTGGGGCTAGACCAATTAACGATGCTTTCGTAGAGGCGATTGAACAGTTTGGAA
ATAAAAGTTACGAAATATTGTATGTAACAGGTGAAGTTCATTATGACAAAGTGATGGAAGCAGTGAAGCAAAAAGGGAAT
CCGAATAATGTTATTATTAAACCTTTCATTCATAATATGCCAGAAGTACTTACAGGTGTAGATCTTGTTGTTTCAAGAGC
TGGGGCAACAACACTTGCAGAATTAACAGCGTTAGGTAAGCCGAGTGTGTTAATTCCGAGTCCGTATGTAACAAATAACC
ATCAGGAAAAAAATGCACGTTCTGTTGTCGATAAAGGAGCAGCAAAAATGTTGCTTGAAAAAGATTTAACAGCTGAAACA
CTTATTCGTGATATTGATGAGATTTTATTAGATGCACAAACATTACAAAATATGAAGCTTGCTGCTGGGCAATTAGGTAT
TCCAGATGCAGCAAATAAGCTGTATGAAGTCATGAATAAGCTTGTAAAAAAATAA

Upstream 100 bases:

>100_bases
GTTTTATAAGACAGGGTTTTTCGTATGTGCGTGAAGAAACAATATGTATATAGAAATAAATACGACTGAAATAAGAAAAA
GAGAAGCGGAGGAGTTAGTA

Downstream 100 bases:

>100_bases
CGTTAGGTGAACGCCCTGCATACTACTGTAATAAGGATGCTGAGTATGGGGGAGATTGTTTATGGAGCAATTAGTAAATG
AGCTTATACAAGCAAATGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 1

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Sequences:

>Translated_364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK
>Mature_364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=31.767955801105, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG1_BACAN (Q81JG5)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_846289.1
- RefSeq:   YP_020691.2
- ProteinModelPortal:   Q81JG5
- EnsemblBacteria:   EBBACT00000012189
- EnsemblBacteria:   EBBACT00000015667
- EnsemblBacteria:   EBBACT00000022700
- GeneID:   1087469
- GeneID:   2819719
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4049
- KEGG:   bar:GBAA_4049
- KEGG:   bat:BAS3761
- TIGR:   BA_4049
- TIGR:   GBAA_4049
- GeneTree:   EBGT00050000001194
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   BANT260799:BAS3761-MONOMER
- BioCyc:   BANT261594:GBAA4049-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39601; Mature: 39601

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVIS
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
GFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIV
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCC
GLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCC
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNAR
CCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
SVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVKK
HHCC
>Mature Secondary Structure
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKAGIPFQSIVIS
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
GFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIV
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCC
GLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCC
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNAR
CCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
SVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629