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The map label for this gene is spoVE [H]

Identifier: 30263913

GI number: 30263913

Start: 3729439

End: 3730530

Strand: Reverse

Name: spoVE [H]

Synonym: BA_4050

Alternate gene names: 30263913

Gene position: 3730530-3729439 (Counterclockwise)

Preceding gene: 30263914

Following gene: 30263912

Centisome position: 71.37

GC content: 38.1

Gene sequence:

>1092_bases
ATGAAGAAAACGCCTGATTTTATTCTCATCATCGTTACACTTGCGTTGTTAACAATCGGAATGATTATGGTTTATAGTGC
GAGTGCGGTTTGGGCCTCTTATAAAATGGGGGACTCATTCTTTTTTGCAAAAAGGCAATTGCTATTCGCAGGTCTTGGTG
TAGTGGCTATGTTTTTTATTATGAAAATTGATTATTGGGTGTGGCGTACGTATTCAAAAGTAATTTTGCTAGTTTGCTTC
ATTCTTCTTATTCTCGTTCTTATTCCTGGAGTAGGTCTTGTTCGAGGAGGAGCGCGAAGTTGGATTGGAATCGGGGCATT
TTCCATTCAACCGTCCGAATTTATGAAGTTTGCGATGATTATTTTCTTAGCGAAATTTTTAGCGGAACGACAAAAATTAA
TTACCTCTTTTAAACGTGGTTTACTACCAGCTCTAGGTTTTGTATTTCTTGCTTTCGGAATGATTATGTTACAGCCAGAT
CTTGGTACAGGAACGGTAATGGTCGGGACATGTATCATTATGATATTTATCTCGGGAGCAAGGGTCTTTCACTTTGCAAT
GTTTGGTTTGCTTGGTGTAGCAGGATTTGTAGGGCTAATTGCATCAGCACCGTATCGGATGAAACGTATTACATCATATT
TAGATCCGTGGTCAGATCCGCTTGGAAGTGGATTTCAAATTATTCAATCGTTACTCGCAATTGGACCGGGTGGATTATTC
GGGCTTGGACTTGGACAAAGTCGACAAAAGTTTCTTTATTTACCTGAACCCCAAACAGACTTTATATTTGCAATCTTATC
CGAGGAATTAGGTTTTATTGGTGGTTCATTTGTGTTATTATTATTTAGTCTATTATTATGGCGTGGGATTCGTATAGCTT
TAGGAGCGCCAGATTTATATGGTACGTTTTTAGCAGTAGGTATTGTGGCGATGATTGCGATTCAAGTAATGATTAATGTT
GGTGTTGTAACAGGATTGATGCCTGTTACGGGTATTACTTTACCGTTTTTAAGTTATGGTGGATCAAGTTTGACATTAAT
GTTAATGGCAGTAGGTGTATTATTAAATATAAGTCGCCATTCTCGCTACTAA

Upstream 100 bases:

>100_bases
ACTTATATAAAGTAAATCAAAACATCAGTAGGCTAACACCTACTGATGTTTTGTTACATAGGGCAAAAGTTTCTGCCTAA
AGAGGTGGTGTTTATGGGTA

Downstream 100 bases:

>100_bases
ACCCTGTTTTATAAGACAGGGTTTTTCGTATGTGCGTGAAGAAACAATATGTATATAGAAATAAATACGACTGAAATAAG
AAAAAGAGAAGCGGAGGAGT

Product: stage V sporulation protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKKTPDFILIIVTLALLTIGMIMVYSASAVWASYKMGDSFFFAKRQLLFAGLGVVAMFFIMKIDYWVWRTYSKVILLVCF
ILLILVLIPGVGLVRGGARSWIGIGAFSIQPSEFMKFAMIIFLAKFLAERQKLITSFKRGLLPALGFVFLAFGMIMLQPD
LGTGTVMVGTCIIMIFISGARVFHFAMFGLLGVAGFVGLIASAPYRMKRITSYLDPWSDPLGSGFQIIQSLLAIGPGGLF
GLGLGQSRQKFLYLPEPQTDFIFAILSEELGFIGGSFVLLLFSLLLWRGIRIALGAPDLYGTFLAVGIVAMIAIQVMINV
GVVTGLMPVTGITLPFLSYGGSSLTLMLMAVGVLLNISRHSRY

Sequences:

>Translated_363_residues
MKKTPDFILIIVTLALLTIGMIMVYSASAVWASYKMGDSFFFAKRQLLFAGLGVVAMFFIMKIDYWVWRTYSKVILLVCF
ILLILVLIPGVGLVRGGARSWIGIGAFSIQPSEFMKFAMIIFLAKFLAERQKLITSFKRGLLPALGFVFLAFGMIMLQPD
LGTGTVMVGTCIIMIFISGARVFHFAMFGLLGVAGFVGLIASAPYRMKRITSYLDPWSDPLGSGFQIIQSLLAIGPGGLF
GLGLGQSRQKFLYLPEPQTDFIFAILSEELGFIGGSFVLLLFSLLLWRGIRIALGAPDLYGTFLAVGIVAMIAIQVMINV
GVVTGLMPVTGITLPFLSYGGSSLTLMLMAVGVLLNISRHSRY
>Mature_363_residues
MKKTPDFILIIVTLALLTIGMIMVYSASAVWASYKMGDSFFFAKRQLLFAGLGVVAMFFIMKIDYWVWRTYSKVILLVCF
ILLILVLIPGVGLVRGGARSWIGIGAFSIQPSEFMKFAMIIFLAKFLAERQKLITSFKRGLLPALGFVFLAFGMIMLQPD
LGTGTVMVGTCIIMIFISGARVFHFAMFGLLGVAGFVGLIASAPYRMKRITSYLDPWSDPLGSGFQIIQSLLAIGPGGLF
GLGLGQSRQKFLYLPEPQTDFIFAILSEELGFIGGSFVLLLFSLLLWRGIRIALGAPDLYGTFLAVGIVAMIAIQVMINV
GVVTGLMPVTGITLPFLSYGGSSLTLMLMAVGVLLNISRHSRY

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=39.1666666666667, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=34.402332361516, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39620; Mature: 39620

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTPDFILIIVTLALLTIGMIMVYSASAVWASYKMGDSFFFAKRQLLFAGLGVVAMFFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MKIDYWVWRTYSKVILLVCFILLILVLIPGVGLVRGGARSWIGIGAFSIQPSEFMKFAMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCHHHHHHHHHH
IFLAKFLAERQKLITSFKRGLLPALGFVFLAFGMIMLQPDLGTGTVMVGTCIIMIFISGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RVFHFAMFGLLGVAGFVGLIASAPYRMKRITSYLDPWSDPLGSGFQIIQSLLAIGPGGLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCE
GLGLGQSRQKFLYLPEPQTDFIFAILSEELGFIGGSFVLLLFSLLLWRGIRIALGAPDLY
ECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCHHH
GTFLAVGIVAMIAIQVMINVGVVTGLMPVTGITLPFLSYGGSSLTLMLMAVGVLLNISRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SRY
CCC
>Mature Secondary Structure
MKKTPDFILIIVTLALLTIGMIMVYSASAVWASYKMGDSFFFAKRQLLFAGLGVVAMFFI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MKIDYWVWRTYSKVILLVCFILLILVLIPGVGLVRGGARSWIGIGAFSIQPSEFMKFAMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCEECCCHHHHHHHHHH
IFLAKFLAERQKLITSFKRGLLPALGFVFLAFGMIMLQPDLGTGTVMVGTCIIMIFISGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RVFHFAMFGLLGVAGFVGLIASAPYRMKRITSYLDPWSDPLGSGFQIIQSLLAIGPGGLF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCE
GLGLGQSRQKFLYLPEPQTDFIFAILSEELGFIGGSFVLLLFSLLLWRGIRIALGAPDLY
ECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCHHH
GTFLAVGIVAMIAIQVMINVGVVTGLMPVTGITLPFLSYGGSSLTLMLMAVGVLLNISRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SRY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]