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The map label for this gene is hutI

Identifier: 30263596

GI number: 30263596

Start: 3411475

End: 3412746

Strand: Reverse

Name: hutI

Synonym: BA_3710

Alternate gene names: 30263596

Gene position: 3412746-3411475 (Counterclockwise)

Preceding gene: 30263597

Following gene: 30263595

Centisome position: 65.29

GC content: 39.94

Gene sequence:

>1272_bases
ATGCTGGACACTTTACTAATCAATATCGGTCAATTACTAACAATGGATCAAGAAGATGGCTTGTTAAGACGGGAAGCGAT
GAACACGCTTCCTGTTATCGAAAATGGTGCGGTTGGAATTGAAAATGGTGTAATCACTTTCGTTGGAACAGCGGAAGAAG
CGAAAGGATTACAAGCGAAAGAGGTTATTGATTGCGGCGGAAAAATGGTTTCTCCTGGCCTTGTTGACCCGCATACTCAT
CTTGTATTTGGTGGATCTCGCGAAAATGAAATCGCACTAAAATTACAAGGAGTTCCGTACTTAGAAATTTTAGAACAAGG
CGGAGGTATTCTTTCAACTGTAAATGCAACGAAACAAGCGTCGAAAGAAGAGCTTGTTCAAAAAGCGAAATTCCATTTAG
ACCGTATGCTATCTTTCGGAGTTACAACTGTAGAAGCGAAGAGTGGTTATGGATTAGATGATGAGACGGAATGGAAACAA
TTAGAGGCAACTGCACAATTACAAAAAGAACATCCAATCGATTTAGTGTCAACGTTTTTAGGTGCTCATGCAGTTCCGAA
GGAGTACAAAGGTAGATCAAAAGAATTTTTACAATGGATGTTAGACCTACTACCAGAAATGAAAGAGAAGCAATTAGCAG
AATTCGTTGATATTTTCTGCGAAACAGGTGTGTTCTCTGTCGAAGAATCAAAAGAGTTTTTATTAAAAGCGAAAGAGCTT
GGCTTTGATGTGAAAATTCATGCGGATGAAATTGATCCTCTTGGTGGTGCGGAAGCAGCAGCTGAAATTGGTGCAGCATC
AGCGGACCATTTAGTTGGTGCTTCTGATAAAGGAATTGAAATGCTTGCAAACTCTAATACAGTAGCCACTTTATTACCAG
GAACAACCTTCTATTTAAATAAAGAAAGCTTTGCTCGCGGTCGTAAAATGATTGATGAAGGTGTTGCGGTAGCTTTAGCC
ACAGACTTTAACCCAGGCAGCTGCCCAACTGAAAACATTCAGCTTATTATGAGCATCGCAATGCTGAAATTGAAAATGAC
ACCAGAGGAAGTTTGGAATGCTGTAACAGTTAACTCTTCTTATGCTATTAATCGAGGCGATGTAGCTGGGAAAATTAGAG
TGGGTCGTAAGGCAGATTTAGTTTTATGGGATGCTTACAATTATGCTTACGTACCGTATCATTACGGTGTAAGTCATGTA
AATACAGTGTGGAAGAATGGTAATATCGCATATACAAGAGGTGAACAATCGTGGAGCACGGCCACTATTTAA

Upstream 100 bases:

>100_bases
GGGTGTTGTTCGTCACGTTGATGCAGGATATGACTTAGCTGTGGAAACTGCGAAAGAAAAAGGCGTTAACATTCCAATGA
TGAAATAAGGAGGAGAAAAC

Downstream 100 bases:

>100_bases
AGAAAAATGCAAAGTTTATTGATCGTGAAGTGACGAAATGGAGTGAGATGATTAAGGATTGGGAGGAAGGCGTGGAAATA
TTCGGTGCTGCCTTAATTGG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI

Sequences:

>Translated_423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI
>Mature_423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=420, Percent_Identity=36.6666666666667, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17555004, Length=449, Percent_Identity=34.9665924276169, Blast_Score=248, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_BACAA (C3P4M0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002867839.1
- ProteinModelPortal:   C3P4M0
- SMR:   C3P4M0
- EnsemblBacteria:   EBBACT00000125553
- GeneID:   7851549
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3737
- GeneTree:   EBGT00050000002251
- ProtClustDB:   PRK09356
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 46171; Mature: 46171

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: BINDING 87-87 BINDING 100-100 BINDING 150-150 BINDING 183-183 BINDING 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAK
CCCCEEECCHHHEEECCCCCHHHHHHHCCCCEECCCCEEECCCEEEEEECHHHHCCCCHH
EVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQA
HHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHCCCCEEEECCHHHHH
SKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
GAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKEL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHC
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLN
CCEEEEECCCCCCCCCHHHHHHHCCCCCCHHCCCCCCCEEEEECCCEEEEEECCEEEEEC
KESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSS
CHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHHCCEEEECCC
YAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWST
EEECCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCHHHHHHEECCCEEEECCCCCCCC
ATI
CCC
>Mature Secondary Structure
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAK
CCCCEEECCHHHEEECCCCCHHHHHHHCCCCEECCCCEEECCCEEEEEECHHHHCCCCHH
EVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQA
HHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHCCCCEEEECCHHHHH
SKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
GAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKEL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHC
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLN
CCEEEEECCCCCCCCCHHHHHHHCCCCCCHHCCCCCCCEEEEECCCEEEEEECCEEEEEC
KESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSS
CHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHHCCEEEECCC
YAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWST
EEECCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCHHHHHHEECCCEEEECCCCCCCC
ATI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA