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The map label for this gene is appA [H]

Identifier: 77748758

GI number: 77748758

Start: 4855361

End: 4856611

Strand: Direct

Name: appA [H]

Synonym: XAC4132

Alternate gene names: 77748758

Gene position: 4855361-4856611 (Clockwise)

Preceding gene: 21244848

Following gene: 21244850

Centisome position: 93.81

GC content: 69.86

Gene sequence:

>1251_bases
GTGCCGCTCACCCCTGCCCAGGCCACCGATGCGACGCCGGACACCCTGGAAAAAGTGGTGATCCTCAAACGCCACGGCGT
GCGTGCGGCGATGTCCAGCCCCGAACGGCTGGGCCGCTATTCGCTGCATCCATGGCCGCATTTCGGCGTGCCGGCCGGTC
ACCTCACCGCCAACGGCGCGCAGCTGGAACGCCTGTTCGGCGACTACTACCGCGCGCACTACACCGCGCTTGGTCTGTTG
AACGGCGATGGCTGCAACCAGGCCTATTACTGGGCCAACCGCACCCAACGCACCATTGCCTCGGCGCAAGCGCTGGCCAG
CACACTGACGCCCGGCTGCGCCGACCCGGTGCATCACGTACCGACCGGCAGTTCCGATGTGTTGTTCGATGGCACCGCTG
CGCTGCGCCAGCCCCAGGCGCGTGCGCGCATGCAGGCGGCCATTGCCGGCCGCATCGGTGGCGATGCGCAGGCTTGGAAT
GCGACCCAGAGCGATGCGCTCGATACGCTCGAACACCTGCTGCTGCAATGCGCGCAACGGCCGTGTCCCGCGCAGGCCGC
GCCCGGCAAGCTGCGCCTGACCACGGTACCGGCCGGGCTGGACGATGCCGGGCCGTCGATTCCCGGTCTCGATGGCCCCG
CCGCGGCTGCCTCGGGCATCACCGAAAGCCTGCTGATGGGCTGGGCCGATGGACAGGACTTCGCCGCGCTGGGTTGGCAA
GGCCTGGACGAAGCCACGCTGCTGCGCGTGTTCGCCCCGCACCAGGCCGAGTTCGCGCTGCGGTTGCGCGCGCCGACCGT
CGCTCGCCTGGCCAGCACCCCGCTGGCCGCACGCCTGCTGGCCACGCTGCAGCAAGGCAACGATGCACACGCCGAGGCCG
ATGCCATCGGCGGCGATGCGCGCCTGGTGGTGGTGTCCGGCCATGACGGCACCCTGACCTTGCTGGCCGGCATGTTCGAT
CTGCACTGGCAGTTGCCCGGCTATCAATCCGACCAGACCGTCCCCGGTGGCGCGCTGGTGTTCGAACGCTGGCGGCGTGC
CGACGGTGAGCGCGTCATTCGCCTGCGCTACACCGCGCAGAGCCTGACGCAGCTGCGCGAACGGGTGCCATTGACGCTGC
AGGCACCACCGCCGAGCGCAGCCATCTTCATTCCCGGCTGCAGCACCGCCACGCCGGCGTACGACTGCCCGCTGCCGCAG
TTCGCCCGCATCGTCCAGGCCGCACTCGATCCGCTCGCCTTGGACCACTGA

Upstream 100 bases:

>100_bases
CCGATTGTTTCGCCTCTCCGCTTCACTCGTCATGGATCTGCCGATGCTTCTGCACTTTTGCCGCCGCGCTACCGCCCTAC
TCGGGCTCGGGCTCGCGCTC

Downstream 100 bases:

>100_bases
GCCCTCCATGCGACGCGCCGGGCCCGACGCGTCGCGTCCATCCGCTGTTCCCCAACCGCACGAGGTCATCATGCTTCAGC
ATCTTCGTTCTCTGCTCAGC

Product: 6-phytase

Products: NA

Alternate protein names: Phosphoanhydride phosphohydrolase; pH 2.5 acid phosphatase; AP; 4-phytase [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MPLTPAQATDATPDTLEKVVILKRHGVRAAMSSPERLGRYSLHPWPHFGVPAGHLTANGAQLERLFGDYYRAHYTALGLL
NGDGCNQAYYWANRTQRTIASAQALASTLTPGCADPVHHVPTGSSDVLFDGTAALRQPQARARMQAAIAGRIGGDAQAWN
ATQSDALDTLEHLLLQCAQRPCPAQAAPGKLRLTTVPAGLDDAGPSIPGLDGPAAAASGITESLLMGWADGQDFAALGWQ
GLDEATLLRVFAPHQAEFALRLRAPTVARLASTPLAARLLATLQQGNDAHAEADAIGGDARLVVVSGHDGTLTLLAGMFD
LHWQLPGYQSDQTVPGGALVFERWRRADGERVIRLRYTAQSLTQLRERVPLTLQAPPPSAAIFIPGCSTATPAYDCPLPQ
FARIVQAALDPLALDH

Sequences:

>Translated_416_residues
MPLTPAQATDATPDTLEKVVILKRHGVRAAMSSPERLGRYSLHPWPHFGVPAGHLTANGAQLERLFGDYYRAHYTALGLL
NGDGCNQAYYWANRTQRTIASAQALASTLTPGCADPVHHVPTGSSDVLFDGTAALRQPQARARMQAAIAGRIGGDAQAWN
ATQSDALDTLEHLLLQCAQRPCPAQAAPGKLRLTTVPAGLDDAGPSIPGLDGPAAAASGITESLLMGWADGQDFAALGWQ
GLDEATLLRVFAPHQAEFALRLRAPTVARLASTPLAARLLATLQQGNDAHAEADAIGGDARLVVVSGHDGTLTLLAGMFD
LHWQLPGYQSDQTVPGGALVFERWRRADGERVIRLRYTAQSLTQLRERVPLTLQAPPPSAAIFIPGCSTATPAYDCPLPQ
FARIVQAALDPLALDH
>Mature_415_residues
PLTPAQATDATPDTLEKVVILKRHGVRAAMSSPERLGRYSLHPWPHFGVPAGHLTANGAQLERLFGDYYRAHYTALGLLN
GDGCNQAYYWANRTQRTIASAQALASTLTPGCADPVHHVPTGSSDVLFDGTAALRQPQARARMQAAIAGRIGGDAQAWNA
TQSDALDTLEHLLLQCAQRPCPAQAAPGKLRLTTVPAGLDDAGPSIPGLDGPAAAASGITESLLMGWADGQDFAALGWQG
LDEATLLRVFAPHQAEFALRLRAPTVARLASTPLAARLLATLQQGNDAHAEADAIGGDARLVVVSGHDGTLTLLAGMFDL
HWQLPGYQSDQTVPGGALVFERWRRADGERVIRLRYTAQSLTQLRERVPLTLQAPPPSAAIFIPGCSTATPAYDCPLPQF
ARIVQAALDPLALDH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histidine acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1787215, Length=433, Percent_Identity=33.0254041570439, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1787237, Length=407, Percent_Identity=25.7985257985258, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000560 [H]

Pfam domain/function: PF00328 Acid_phosphat_A [H]

EC number: =3.1.3.2; =3.1.3.26 [H]

Molecular weight: Translated: 44167; Mature: 44036

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTPAQATDATPDTLEKVVILKRHGVRAAMSSPERLGRYSLHPWPHFGVPAGHLTANGA
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCCCCCCCCCEECCHH
QLERLFGDYYRAHYTALGLLNGDGCNQAYYWANRTQRTIASAQALASTLTPGCADPVHHV
HHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PTGSSDVLFDGTAALRQPQARARMQAAIAGRIGGDAQAWNATQSDALDTLEHLLLQCAQR
CCCCCCEEECCHHHHHCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHCC
PCPAQAAPGKLRLTTVPAGLDDAGPSIPGLDGPAAAASGITESLLMGWADGQDFAALGWQ
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
GLDEATLLRVFAPHQAEFALRLRAPTVARLASTPLAARLLATLQQGNDAHAEADAIGGDA
CCCHHHHHEEECCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCCE
RLVVVSGHDGTLTLLAGMFDLHWQLPGYQSDQTVPGGALVFERWRRADGERVIRLRYTAQ
EEEEEECCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECHH
SLTQLRERVPLTLQAPPPSAAIFIPGCSTATPAYDCPLPQFARIVQAALDPLALDH
HHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
PLTPAQATDATPDTLEKVVILKRHGVRAAMSSPERLGRYSLHPWPHFGVPAGHLTANGA
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCCCCCCCCCEECCHH
QLERLFGDYYRAHYTALGLLNGDGCNQAYYWANRTQRTIASAQALASTLTPGCADPVHHV
HHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
PTGSSDVLFDGTAALRQPQARARMQAAIAGRIGGDAQAWNATQSDALDTLEHLLLQCAQR
CCCCCCEEECCHHHHHCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHCC
PCPAQAAPGKLRLTTVPAGLDDAGPSIPGLDGPAAAASGITESLLMGWADGQDFAALGWQ
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
GLDEATLLRVFAPHQAEFALRLRAPTVARLASTPLAARLLATLQQGNDAHAEADAIGGDA
CCCHHHHHEEECCCCCCEEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCCE
RLVVVSGHDGTLTLLAGMFDLHWQLPGYQSDQTVPGGALVFERWRRADGERVIRLRYTAQ
EEEEEECCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECHH
SLTQLRERVPLTLQAPPPSAAIFIPGCSTATPAYDCPLPQFARIVQAALDPLALDH
HHHHHHHHCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168385; 8905232; 9278503; 3038201; 1658595; 8387749; 10696472; 1429631; 10655611 [H]