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The map label for this gene is fusE [H]

Identifier: 21245017

GI number: 21245017

Start: 5089676

End: 5090620

Strand: Direct

Name: fusE [H]

Synonym: XAC4305

Alternate gene names: 21245017

Gene position: 5089676-5090620 (Clockwise)

Preceding gene: 21245016

Following gene: 21245018

Centisome position: 98.34

GC content: 69.21

Gene sequence:

>945_bases
TTGGATGCAATCGTGAAAAAGCTGATCAAGACCGCGGGGCCGGCACTGCTGACCCTGTCAATGGTGGTGGTGGCCGCGTT
GGTGTTGCAGCACCTGTGGCGGTATTACATGCAGGCGCCGTGGACGCGCGATGCGCACGTGGGCGCCGATGTGGTGCAGG
TGGCGCCGGATGTCTCCGGGCTGGTGGAGTCGGTGGCCGTGGCCGACAACCAGCCGGTGAGGCGCGGGCAATTGCTGTTC
GTGGTGGACCGCGCGCGCTACGCGATCGCGCTGGAACAGGCGCGCGCCGCGCTGGCCGAACGCCGGGCCACGCTGACGCA
GTTGCGCCGCGAGATCGCGCGCGACCGCAGCCTGCAGGACCTGGTCGCCGCCGAAGATGCCGAAGTGCGCCGCTCCAACG
TACAAAAGGCGCAGGCCGCAGTGGCCACCGCGCAATCGGCGGTGGATCTGGCCCAGCTCAACCTGGACCGCACCCAGGTG
CGCAGCCCGGCCGACGGTCGCGTCAGCGACCGCACCGTGCGGGTGGGCGACTACGTCAACGCCGGGCGTCCGGTGGTGGC
GGTGCTGGACACCGGCTCGTTCCGTGTCGATGGCTACTTCGAAGAAACCCGCCTGCAGGGCGTGCACCCCGGCCAGCGCG
TGGACGTACAGCTGATGGGCGAGCCGGTCACGCTGCAGGGGCATGTACAGAGCATCGCCGCCGGGATCGAAGACCGTTAC
CGCAGCGGCAGCGCAGGCGCATTGCCCAATGTCACGCCGGCGTTCGATTGGGTACGGCTGGCGCAACGCATCCCGGTGCG
CATCGTGCTGGATCGCGTACCTGCGCATGTGCAGTTGATCGCAGGGCGCACTGCCACGGTGAGCATTCTGCCCGACACGG
CCAATACGGCTCCGGCAACCCCGGCCGTCGCGCCTGCCCGTGTGCAGGCCAAGGCGGCGCCATGA

Upstream 100 bases:

>100_bases
TGCTGACCCGCGCCGGCGCCTACCGCTACATCTGGCACCCGGCGCTGTTCAACCTGGCGCTGTACATCGCACTGCTGGGC
GGCCTGTTCTTCCTTACCCG

Downstream 100 bases:

>100_bases
ACCGCACGATCTTGCGTCCGCTGGGAGTGGCCGCACTGCTGAGCATGCTCACTGCCTGCAGCACGGTCGGCCCGAACTAC
GCCGTGCCGGCCGAGTCGGC

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDAIVKKLIKTAGPALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVVQVAPDVSGLVESVAVADNQPVRRGQLLF
VVDRARYAIALEQARAALAERRATLTQLRREIARDRSLQDLVAAEDAEVRRSNVQKAQAAVATAQSAVDLAQLNLDRTQV
RSPADGRVSDRTVRVGDYVNAGRPVVAVLDTGSFRVDGYFEETRLQGVHPGQRVDVQLMGEPVTLQGHVQSIAAGIEDRY
RSGSAGALPNVTPAFDWVRLAQRIPVRIVLDRVPAHVQLIAGRTATVSILPDTANTAPATPAVAPARVQAKAAP

Sequences:

>Translated_314_residues
MDAIVKKLIKTAGPALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVVQVAPDVSGLVESVAVADNQPVRRGQLLF
VVDRARYAIALEQARAALAERRATLTQLRREIARDRSLQDLVAAEDAEVRRSNVQKAQAAVATAQSAVDLAQLNLDRTQV
RSPADGRVSDRTVRVGDYVNAGRPVVAVLDTGSFRVDGYFEETRLQGVHPGQRVDVQLMGEPVTLQGHVQSIAAGIEDRY
RSGSAGALPNVTPAFDWVRLAQRIPVRIVLDRVPAHVQLIAGRTATVSILPDTANTAPATPAVAPARVQAKAAP
>Mature_314_residues
MDAIVKKLIKTAGPALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVVQVAPDVSGLVESVAVADNQPVRRGQLLF
VVDRARYAIALEQARAALAERRATLTQLRREIARDRSLQDLVAAEDAEVRRSNVQKAQAAVATAQSAVDLAQLNLDRTQV
RSPADGRVSDRTVRVGDYVNAGRPVVAVLDTGSFRVDGYFEETRLQGVHPGQRVDVQLMGEPVTLQGHVQSIAAGIEDRY
RSGSAGALPNVTPAFDWVRLAQRIPVRIVLDRVPAHVQLIAGRTATVSILPDTANTAPATPAVAPARVQAKAAP

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=273, Percent_Identity=40.6593406593407, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1789637, Length=291, Percent_Identity=39.8625429553265, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1790519, Length=315, Percent_Identity=30.7936507936508, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788711, Length=321, Percent_Identity=26.791277258567, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789041, Length=297, Percent_Identity=26.9360269360269, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082036, Length=154, Percent_Identity=30.5194805194805, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 33836; Mature: 33836

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIVKKLIKTAGPALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVVQVAPDVSG
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHH
LVESVAVADNQPVRRGQLLFVVDRARYAIALEQARAALAERRATLTQLRREIARDRSLQD
HHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LVAAEDAEVRRSNVQKAQAAVATAQSAVDLAQLNLDRTQVRSPADGRVSDRTVRVGDYVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCCC
AGRPVVAVLDTGSFRVDGYFEETRLQGVHPGQRVDVQLMGEPVTLQGHVQSIAAGIEDRY
CCCCEEEEEECCCEEECCEEHHHHCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
RSGSAGALPNVTPAFDWVRLAQRIPVRIVLDRVPAHVQLIAGRTATVSILPDTANTAPAT
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCC
PAVAPARVQAKAAP
CCCCCCCCCCCCCC
>Mature Secondary Structure
MDAIVKKLIKTAGPALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVVQVAPDVSG
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHH
LVESVAVADNQPVRRGQLLFVVDRARYAIALEQARAALAERRATLTQLRREIARDRSLQD
HHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LVAAEDAEVRRSNVQKAQAAVATAQSAVDLAQLNLDRTQVRSPADGRVSDRTVRVGDYVN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCCC
AGRPVVAVLDTGSFRVDGYFEETRLQGVHPGQRVDVQLMGEPVTLQGHVQSIAAGIEDRY
CCCCEEEEEECCCEEECCEEHHHHCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
RSGSAGALPNVTPAFDWVRLAQRIPVRIVLDRVPAHVQLIAGRTATVSILPDTANTAPAT
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCC
PAVAPARVQAKAAP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]