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The map label for this gene is bioH [C]

Identifier: 21244938

GI number: 21244938

Start: 4979582

End: 4980448

Strand: Direct

Name: bioH [C]

Synonym: XAC4221

Alternate gene names: 21244938

Gene position: 4979582-4980448 (Clockwise)

Preceding gene: 21244937

Following gene: 77748765

Centisome position: 96.21

GC content: 68.74

Gene sequence:

>867_bases
GTGAAGTTGGAGCCGTTTGCATGCGACCTGGCCATCGGCCGGGTCACCGGATTGCGCAACCAAAATCGCGGCCCGCGCCG
GGTGCTGGCCTTGCATGGCTGGCTGGATAACGCGGCCAGCTTCGTGCCACTGAGCGCGCATCTGCACGCGCAGGAGCTGG
ACCTGGTGCTGCTGGATCTGCCCGGCCACGGCCACAGCGCCTGGCTGCCGACAGGCGCCGAATACACGCTCAGCAGCGCG
ATCGCCCTGTTGTTGCAGGTCGCCGATGCCCTGGGCTGGGAGCGCTTCACCCTGCTCGGCCACTCGATGGGCGGCGGCAT
TGCCAGCCTGCTGGCCGCCGCCGCGCCCGAGCGCGTGGAGGCCTTGATCGCCATCGAGGCGCTGGGCGCGCTGGCCGAGC
CCGTGGAAAACACCGCCACACGCCTGCGCGATGCAGTCGCGTCGGCACGCACGCTAGCGCAGCGGCCGCTGCGGGTGTTT
GCGTCGATGGAAATGCCGGTACGCGCGCGCATGATGGCCAACCAACTCACCGAACCGGCTGCACGGCTGCTGGTCGAACG
CGGCGTACGCGTGGTGGAAGGTGGCTACAGCTGGTGCAGCGATCCGCGCCTGACCCTGCCCACCGCCATCCGCATGACCG
AAGCGCAGATCGACGTGCTGCTGGCCTCCATCGCCTGCCCCGCCCAGACGATCTTCGCCACGCCCGCACAGCCGTATTTC
CCGGACGCATTGCGCGACCACCGCGTGGCGATGATGCGCGATGCGCGCCTGCAGCTGCTGCCCGGCACCCACCACGTGCA
TATGGAAGCACCGGAAGCGGTCGCGGCGGTGATCAACGCCTTTTTGGATGGTTTGCGTCACGCGTGA

Upstream 100 bases:

>100_bases
CCGAAACGCTGGCCGAACGTGGCGCCACCCTCAGCTACATCCCCTGCCTCAACGCCAGCGATGCGCATGCGCACGCGCTG
GCCGCCATGGCGCGCCGCGC

Downstream 100 bases:

>100_bases
TGCGCAGATGCGAATCGCGCAGGTGAACTAGATCCACGGCAGATGCCGCCCGTGTCGTGGGCGTACTTGAATCCTTCGAT
CGGTGGCATGCGCCGTGGAC

Product: hydrolase

Products: NA

Alternate protein names: Hydrolase; Alpha/Beta Fold Family Hydrolase; Hydrolase Alpha/Beta Fold Family; Alpha/Beta Hydrolase; Hydrolase/Acyltransferase; Alpha/Beta Hydrolase Fold Protein; Lipase A; Lipase; Hydrolase Protein; Alpha/Beta Fold Superfamily Hydrolase; Alpha/Beta Hydrolase Family Protein; Lipase LipA; Hydrolase Alpha/Beta Fold Family Protein; Epoxide Hydrolase; Alpha/Beta Superfamily Hydrolase; Alpha/Beta Fold Hydrolase Family Protein

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKLEPFACDLAIGRVTGLRNQNRGPRRVLALHGWLDNAASFVPLSAHLHAQELDLVLLDLPGHGHSAWLPTGAEYTLSSA
IALLLQVADALGWERFTLLGHSMGGGIASLLAAAAPERVEALIAIEALGALAEPVENTATRLRDAVASARTLAQRPLRVF
ASMEMPVRARMMANQLTEPAARLLVERGVRVVEGGYSWCSDPRLTLPTAIRMTEAQIDVLLASIACPAQTIFATPAQPYF
PDALRDHRVAMMRDARLQLLPGTHHVHMEAPEAVAAVINAFLDGLRHA

Sequences:

>Translated_288_residues
MKLEPFACDLAIGRVTGLRNQNRGPRRVLALHGWLDNAASFVPLSAHLHAQELDLVLLDLPGHGHSAWLPTGAEYTLSSA
IALLLQVADALGWERFTLLGHSMGGGIASLLAAAAPERVEALIAIEALGALAEPVENTATRLRDAVASARTLAQRPLRVF
ASMEMPVRARMMANQLTEPAARLLVERGVRVVEGGYSWCSDPRLTLPTAIRMTEAQIDVLLASIACPAQTIFATPAQPYF
PDALRDHRVAMMRDARLQLLPGTHHVHMEAPEAVAAVINAFLDGLRHA
>Mature_288_residues
MKLEPFACDLAIGRVTGLRNQNRGPRRVLALHGWLDNAASFVPLSAHLHAQELDLVLLDLPGHGHSAWLPTGAEYTLSSA
IALLLQVADALGWERFTLLGHSMGGGIASLLAAAAPERVEALIAIEALGALAEPVENTATRLRDAVASARTLAQRPLRVF
ASMEMPVRARMMANQLTEPAARLLVERGVRVVEGGYSWCSDPRLTLPTAIRMTEAQIDVLLASIACPAQTIFATPAQPYF
PDALRDHRVAMMRDARLQLLPGTHHVHMEAPEAVAAVINAFLDGLRHA

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI18777795, Length=286, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137390, Length=291, Percent_Identity=29.553264604811, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357291, Length=277, Percent_Identity=29.6028880866426, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667992, Length=277, Percent_Identity=29.6028880866426, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655874, Length=289, Percent_Identity=26.643598615917, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667999, Length=287, Percent_Identity=25.4355400696864, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356937, Length=290, Percent_Identity=25.5172413793103, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24655886, Length=132, Percent_Identity=34.8484848484849, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356953, Length=309, Percent_Identity=24.5954692556634, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31060; Mature: 31060

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEPFACDLAIGRVTGLRNQNRGPRRVLALHGWLDNAASFVPLSAHLHAQELDLVLLDL
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHCCCCCCCEEEEEC
PGHGHSAWLPTGAEYTLSSAIALLLQVADALGWERFTLLGHSMGGGIASLLAAAAPERVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCHHHHH
ALIAIEALGALAEPVENTATRLRDAVASARTLAQRPLRVFASMEMPVRARMMANQLTEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLLVERGVRVVEGGYSWCSDPRLTLPTAIRMTEAQIDVLLASIACPAQTIFATPAQPYF
HHHHHHCCCEEEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
PDALRDHRVAMMRDARLQLLPGTHHVHMEAPEAVAAVINAFLDGLRHA
CHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLEPFACDLAIGRVTGLRNQNRGPRRVLALHGWLDNAASFVPLSAHLHAQELDLVLLDL
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEHHHCCCCCCCEEEEEC
PGHGHSAWLPTGAEYTLSSAIALLLQVADALGWERFTLLGHSMGGGIASLLAAAAPERVE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCHHHHH
ALIAIEALGALAEPVENTATRLRDAVASARTLAQRPLRVFASMEMPVRARMMANQLTEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLLVERGVRVVEGGYSWCSDPRLTLPTAIRMTEAQIDVLLASIACPAQTIFATPAQPYF
HHHHHHCCCEEEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
PDALRDHRVAMMRDARLQLLPGTHHVHMEAPEAVAAVINAFLDGLRHA
CHHHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA