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The map label for this gene is guaA [H]

Identifier: 21244931

GI number: 21244931

Start: 4973944

End: 4974696

Strand: Direct

Name: guaA [H]

Synonym: XAC4214

Alternate gene names: 21244931

Gene position: 4973944-4974696 (Clockwise)

Preceding gene: 21244929

Following gene: 77748764

Centisome position: 96.1

GC content: 70.39

Gene sequence:

>753_bases
ATGTCCGTTTTGCCGTTCCTGATCATCGAAACCGGGCAGCCCGTGCCGGAGATGAAGCGATACGGCCGTTTTCCGCACTG
GATCCGCGTGGCGGCCGGGCTGGCCGAGCAGGAAACGGTGGCCATCGACGTCGCCAATGGCGACGCGCTGCCCGACCCGG
CCGACTTTGCCGGCATCATCGTCAGCGGTTCGGCGGCCTTCGTCACCGACCGCGCCGACTGGAGCGAACGCAGTGCCGAA
TGGCTGCGCCATGCCGCCCATCAAGGCATGCCGCTGCTGGGCATCTGCTACGGGCACCAGTTGCTGGCGCACGCGCTGGG
CGGCGAGGTCGACTACAACCCGGCCGGGCGCGAATCCGGCACCATCGCGCTGGAGCTGCACCCGCCGGCCGAGCAGGATC
CTTTATTCGCAGGGCTTCCGCCGCAGTTCCCGGCCCATGCCACCCATCTGCAGACGGTCGTGCGTGCCCCGGACGGCGCC
GTCGTGCTGGCGCACTCCCGGCAGGACCGCTGCCATGCCTTCCGCTGGGGCCGGGCCACCTGGGGCGTCCAGTTCCACCC
CGAATTCGCCACCCACCACATGCGCGGCTATGTGCAGGCGCGTGCCGACTGCATCGCCCGCCACGGACGTTGCGCCCGCA
CGGTCGCCCGCGAGGTCACCGCCGCCCCCATCGCGCGCAAGCTGTTGCGCCGCTTCGTGCATCACGCACGCCGGCTGCAG
ACAGTGAGCGCTCGTCCCGCCGCGCACACCTAA

Upstream 100 bases:

>100_bases
TCGGCAATGACCCGCAGCGCGCGTCTTGGAGTGGCGCTTGAAAAAAACGCGTCGCTGCCGCCTACAATCGGGGGCATCTG
TTGTGTCCGGATCTTCGCGC

Downstream 100 bases:

>100_bases
AAGCAGCGATAATCGCGTGACGCCGGATGGTCCGGCGCGCGTATCGATCCGGAATGGGAATGAGCGAAATTCGTAAGGTG
CCGGCATCTGCCGGCGCAGA

Product: glutamine amidotransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSVLPFLIIETGQPVPEMKRYGRFPHWIRVAAGLAEQETVAIDVANGDALPDPADFAGIIVSGSAAFVTDRADWSERSAE
WLRHAAHQGMPLLGICYGHQLLAHALGGEVDYNPAGRESGTIALELHPPAEQDPLFAGLPPQFPAHATHLQTVVRAPDGA
VVLAHSRQDRCHAFRWGRATWGVQFHPEFATHHMRGYVQARADCIARHGRCARTVAREVTAAPIARKLLRRFVHHARRLQ
TVSARPAAHT

Sequences:

>Translated_250_residues
MSVLPFLIIETGQPVPEMKRYGRFPHWIRVAAGLAEQETVAIDVANGDALPDPADFAGIIVSGSAAFVTDRADWSERSAE
WLRHAAHQGMPLLGICYGHQLLAHALGGEVDYNPAGRESGTIALELHPPAEQDPLFAGLPPQFPAHATHLQTVVRAPDGA
VVLAHSRQDRCHAFRWGRATWGVQFHPEFATHHMRGYVQARADCIARHGRCARTVAREVTAAPIARKLLRRFVHHARRLQ
TVSARPAAHT
>Mature_249_residues
SVLPFLIIETGQPVPEMKRYGRFPHWIRVAAGLAEQETVAIDVANGDALPDPADFAGIIVSGSAAFVTDRADWSERSAEW
LRHAAHQGMPLLGICYGHQLLAHALGGEVDYNPAGRESGTIALELHPPAEQDPLFAGLPPQFPAHATHLQTVVRAPDGAV
VLAHSRQDRCHAFRWGRATWGVQFHPEFATHHMRGYVQARADCIARHGRCARTVAREVTAAPIARKLLRRFVHHARRLQT
VSARPAAHT

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 27452; Mature: 27320

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLPFLIIETGQPVPEMKRYGRFPHWIRVAAGLAEQETVAIDVANGDALPDPADFAGII
CCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEE
VSGSAAFVTDRADWSERSAEWLRHAAHQGMPLLGICYGHQLLAHALGGEVDYNPAGRESG
EECCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCC
TIALELHPPAEQDPLFAGLPPQFPAHATHLQTVVRAPDGAVVLAHSRQDRCHAFRWGRAT
EEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCEE
WGVQFHPEFATHHMRGYVQARADCIARHGRCARTVAREVTAAPIARKLLRRFVHHARRLQ
CCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSARPAAHT
HHCCCCCCCC
>Mature Secondary Structure 
SVLPFLIIETGQPVPEMKRYGRFPHWIRVAAGLAEQETVAIDVANGDALPDPADFAGII
CCCCEEEEECCCCCHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEE
VSGSAAFVTDRADWSERSAEWLRHAAHQGMPLLGICYGHQLLAHALGGEVDYNPAGRESG
EECCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCC
TIALELHPPAEQDPLFAGLPPQFPAHATHLQTVVRAPDGAVVLAHSRQDRCHAFRWGRAT
EEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCEE
WGVQFHPEFATHHMRGYVQARADCIARHGRCARTVAREVTAAPIARKLLRRFVHHARRLQ
CCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSARPAAHT
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA