Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 21244803

GI number: 21244803

Start: 4790376

End: 4791575

Strand: Direct

Name: fabF [H]

Synonym: XAC4086

Alternate gene names: 21244803

Gene position: 4790376-4791575 (Clockwise)

Preceding gene: 21244797

Following gene: 21244804

Centisome position: 92.56

GC content: 69.75

Gene sequence:

>1200_bases
ATGGCCCCGGTTGCCGTCACCGCGTTCACTTCCACCACCGCGCTCGGCGCCGGGCTCGCCGCCCAGGCCGCCGCGTTGAC
CGCTCGCCGCAGCGGCCTGCGTCGCAACGATTTCGGCCCGCAACCGCTGCTGCCCTGCTGGGTTGGCCGCGTCGATGGCG
TTGAAGACGTTGTACTGCCCGATTCTCTGCAAGAGTGGGATTGCCGCAACAACCGCCTGGCCTGGCTGGCCCTGCAGCAG
GACGGGATGGCGCAGGCCGTGCAGGCCGCTGCGCAACGTTGCGGCGCCGAGCGCGTGGCGGTGATCATCGGCACCTCCAC
GTCCAGCATCGGCGCCAGCGAAGAAGCGTATACGCGGCTGGTCGACGACGCCGACGGTGCGCGCTTTCCCGAGGATCTGA
ATCGCCCGATCGTGCACACCCCGCATTCGCTGGGCGATTTCGTGCAGCACGCCACCGGCCTGCGTGGCCCGTGCGTCACC
GTGGCCACGGCCTGTTCGTCCAGCGCCAAGGTGTTCGCCCAGGCGGCGCGGCTGATGGATGCCGGCGTGATCGATGCGGC
GCTGGTCGGCGGCGTGGACACCTTGTGCGGCAGCGTGCTGTTCGGCTTCAACTCGCTGCAGGTGGTGGCGCCGGAGATGT
GCCAGCCGTTCGATGCACGCCGGGTCGGCCTGAGCCTGGGCGAGGCCGGCGGCTTTGCGCTGCTCGAACGCCCGGCCGCC
GCACCGGATGCCACGCTCTGGCTGTACGGCTACGGCGAATCCAGCGACGCGCACCATATGTCGGCCCCGCATCCGCAAGG
GCTGGGCGCGCAGCTGGCGATGCGCGGTGCGCTCGACCGCGCCGGTCTGGAGCCAGCCGCGGTGGGCTATCTGAATCTGC
ACGGCACCGCCACGCCGGCCAACGACAGCGTGGAAGCCGCCGCAGTGGCAGCGATCTTCCCCGGCACCTTGCACGCCAGT
TCGACCAAGGCCTGGACCGGCCACACCCTGGGTGCGGCGGGCATCGTCGAATCGGTGATCGCACTGCTCGCGCTGCGCGA
CGACGTGCTGCCCGGCACGCTCAACAGCGATATCCCCGACCCGGCCTGTGGCCCGCAAATCCGCTTCGACAACGCCCATG
CCCGCATCGACTACGCCATGAACAACTCTTTCGGTTTTGGCGGCAACAACTGTTCGCTGCTGTTCGGGCGGGCCCGCTGA

Upstream 100 bases:

>100_bases
TTCAGTTGCGCCGTCCACGGGACCCACGCGCGCCATCGATATACTGGCCGCACTTTTTGCCAGCCAGACCATCGTGAGCC
AAGCGCAGCATTCGTCCCAG

Downstream 100 bases:

>100_bases
TGCTGGCCGCGACCATCGAAGGGATCGGCTTCTGGACCCAGGGTCTGCCCAACTGGGACGCTGCCAGCGCCTTCGCACGC
GGCGGCGCGCTGCAGGACAC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MAPVAVTAFTSTTALGAGLAAQAAALTARRSGLRRNDFGPQPLLPCWVGRVDGVEDVVLPDSLQEWDCRNNRLAWLALQQ
DGMAQAVQAAAQRCGAERVAVIIGTSTSSIGASEEAYTRLVDDADGARFPEDLNRPIVHTPHSLGDFVQHATGLRGPCVT
VATACSSSAKVFAQAARLMDAGVIDAALVGGVDTLCGSVLFGFNSLQVVAPEMCQPFDARRVGLSLGEAGGFALLERPAA
APDATLWLYGYGESSDAHHMSAPHPQGLGAQLAMRGALDRAGLEPAAVGYLNLHGTATPANDSVEAAAVAAIFPGTLHAS
STKAWTGHTLGAAGIVESVIALLALRDDVLPGTLNSDIPDPACGPQIRFDNAHARIDYAMNNSFGFGGNNCSLLFGRAR

Sequences:

>Translated_399_residues
MAPVAVTAFTSTTALGAGLAAQAAALTARRSGLRRNDFGPQPLLPCWVGRVDGVEDVVLPDSLQEWDCRNNRLAWLALQQ
DGMAQAVQAAAQRCGAERVAVIIGTSTSSIGASEEAYTRLVDDADGARFPEDLNRPIVHTPHSLGDFVQHATGLRGPCVT
VATACSSSAKVFAQAARLMDAGVIDAALVGGVDTLCGSVLFGFNSLQVVAPEMCQPFDARRVGLSLGEAGGFALLERPAA
APDATLWLYGYGESSDAHHMSAPHPQGLGAQLAMRGALDRAGLEPAAVGYLNLHGTATPANDSVEAAAVAAIFPGTLHAS
STKAWTGHTLGAAGIVESVIALLALRDDVLPGTLNSDIPDPACGPQIRFDNAHARIDYAMNNSFGFGGNNCSLLFGRAR
>Mature_398_residues
APVAVTAFTSTTALGAGLAAQAAALTARRSGLRRNDFGPQPLLPCWVGRVDGVEDVVLPDSLQEWDCRNNRLAWLALQQD
GMAQAVQAAAQRCGAERVAVIIGTSTSSIGASEEAYTRLVDDADGARFPEDLNRPIVHTPHSLGDFVQHATGLRGPCVTV
ATACSSSAKVFAQAARLMDAGVIDAALVGGVDTLCGSVLFGFNSLQVVAPEMCQPFDARRVGLSLGEAGGFALLERPAAA
PDATLWLYGYGESSDAHHMSAPHPQGLGAQLAMRGALDRAGLEPAAVGYLNLHGTATPANDSVEAAAVAAIFPGTLHASS
TKAWTGHTLGAAGIVESVIALLALRDDVLPGTLNSDIPDPACGPQIRFDNAHARIDYAMNNSFGFGGNNCSLLFGRAR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=263, Percent_Identity=35.361216730038, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI223972627, Length=151, Percent_Identity=39.7350993377483, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI41872631, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787337, Length=263, Percent_Identity=41.06463878327, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788663, Length=259, Percent_Identity=32.046332046332, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=31.3253012048193, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=36.4341085271318, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17550940, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=269, Percent_Identity=25.6505576208178, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=350, Percent_Identity=34, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24644341, Length=262, Percent_Identity=34.7328244274809, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI221330659, Length=257, Percent_Identity=27.6264591439689, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920632, Length=257, Percent_Identity=27.6264591439689, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24581345, Length=264, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41291; Mature: 41160

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVAVTAFTSTTALGAGLAAQAAALTARRSGLRRNDFGPQPLLPCWVGRVDGVEDVVLP
CCCEEEEEECHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCEECC
DSLQEWDCRNNRLAWLALQQDGMAQAVQAAAQRCGAERVAVIIGTSTSSIGASEEAYTRL
CCHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
VDDADGARFPEDLNRPIVHTPHSLGDFVQHATGLRGPCVTVATACSSSAKVFAQAARLMD
HCCCCCCCCCHHHCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
AGVIDAALVGGVDTLCGSVLFGFNSLQVVAPEMCQPFDARRVGLSLGEAGGFALLERPAA
CCHHHHHHHCCHHHHHHHHHHCCCCCEEECHHHCCCCCHHHHCCEECCCCCCCEEECCCC
APDATLWLYGYGESSDAHHMSAPHPQGLGAQLAMRGALDRAGLEPAAVGYLNLHGTATPA
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
NDSVEAAAVAAIFPGTLHASSTKAWTGHTLGAAGIVESVIALLALRDDVLPGTLNSDIPD
CCCHHHHHEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PACGPQIRFDNAHARIDYAMNNSFGFGGNNCSLLFGRAR
CCCCCEEEECCCCEEEEEEECCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
APVAVTAFTSTTALGAGLAAQAAALTARRSGLRRNDFGPQPLLPCWVGRVDGVEDVVLP
CCEEEEEECHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCEECC
DSLQEWDCRNNRLAWLALQQDGMAQAVQAAAQRCGAERVAVIIGTSTSSIGASEEAYTRL
CCHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHH
VDDADGARFPEDLNRPIVHTPHSLGDFVQHATGLRGPCVTVATACSSSAKVFAQAARLMD
HCCCCCCCCCHHHCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
AGVIDAALVGGVDTLCGSVLFGFNSLQVVAPEMCQPFDARRVGLSLGEAGGFALLERPAA
CCHHHHHHHCCHHHHHHHHHHCCCCCEEECHHHCCCCCHHHHCCEECCCCCCCEEECCCC
APDATLWLYGYGESSDAHHMSAPHPQGLGAQLAMRGALDRAGLEPAAVGYLNLHGTATPA
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
NDSVEAAAVAAIFPGTLHASSTKAWTGHTLGAAGIVESVIALLALRDDVLPGTLNSDIPD
CCCHHHHHEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PACGPQIRFDNAHARIDYAMNNSFGFGGNNCSLLFGRAR
CCCCCEEEECCCCEEEEEEECCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA