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The map label for this gene is ygiY [H]

Identifier: 21244693

GI number: 21244693

Start: 4669041

End: 4670450

Strand: Direct

Name: ygiY [H]

Synonym: XAC3975

Alternate gene names: 21244693

Gene position: 4669041-4670450 (Clockwise)

Preceding gene: 21244692

Following gene: 21244694

Centisome position: 90.21

GC content: 64.82

Gene sequence:

>1410_bases
ATGGGTGGCGCTGAGCGCACACGAATACCGCCTGCTGCTGGCGTTGATGGAACGTGCCGGACGCGTGGTCACCAAGGATC
AGCTGGAAGAAGGCATCTATGGCGGCCCATCCGAAGGGGGCAGCAACATGATCGCGGTGTATGTGCACCAGTTGCGGCGC
AAGCTGGGCGATGCGCTGATCTCCACCGTCTATGGCCAGGGCTACATGGTCGGAAAGACCCCGGAATGAAGTCGCTGCAG
GCACGCATGCTGGCGGCGCTGGCCGCGATCGTTCTGCTGAGCTGGTCCACCTCTCTGTGGATCCTGGTCGCACTGGTCAC
CCAGGGTCATCACAGCGTGTTCGAGCAGGAACTCAACCTGCTCGGCGATCAACTGCTCGCCACCTTGCCCGACGCGCTCC
AGCACCGCTTCGATACGCAGACAGAGCCGCCCGACGCGGCAACCACGCCGACCCCGATCGGCAACCCATCCTCGCGCATG
AGCGTGAAGCAGACCCTGATCGCAGTGGTGCTCAACACCGTGCAATTGGGCATCCTGGGGCTATTGATGTGGTGGGCCGT
GCGGACCTCGCTGGGGCCGCTGCGCGCCCTGTCCGGCGCCATCGCGCAACGCACCGGCCTGGATACCGAGCCGGTGCCGC
TGGCACAGGCGCCCGACGAAATTCGCCCGCTGATCGCCTCGTTCAACACCTTGCTGGCGCGGGTGGAACAAGCCGTCCAG
GCCGAACGCGATTTCGTCGCCGATGCCGCGCACGAACTGCGCACGCCGCTCTCGGCACTGCATGCCTACGCCGAGGTCGC
ATTGCGCGCGCCCACACTGGACGCCAAGGACGCCGCGCTGCGCCAACTGCTGGAAACCGCGCGTCGCAGTAACCGGCTGG
CCGAACAATTGCTGGATCTGGCACGACTGGATGCCGGCATCAGTTCAGCCGCCTATCATCAAGTCGAAATGGGCGAGCTA
ATCTCGCATGTGCTGGACGAATTCAGCGTGCAGGCCAATACGCGCCAGATGCAGTTGCAGGTTGAGGCATCGCCCTGCCT
GGTGCGTTGCGATGTGGATGCAGTGGGCATTCTGATCCGCAACCTGGTCGACAACGCCATCCGCTATGGCCGACTGCATG
GCAAGGTGGAAGTGAGCTGCGGCTATTGTTTGCGCGCTGACGTCCTGCACCCCTTCTTGCAGGTCAGCGATGACGGCCCC
GGCGTACCCGAAAGCGCGCAGGCCGCTATTTTCGAGCGGTTTTATCGCGTGCCCGGCAGCGCAGTACAGGGCAGTGGAAT
CGGGTTGTCGCTGGTCGCCGGCATTGCGCGCCTGCACGGAGCCACGATCGAAGCCGGCGACGGCAACGATGGACGCGGGC
TGTGCGTACGCGTGGTGTTTGCCGGCGACCACCCCGCCAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GGGCGGTCACCCGGCGCAGCCAGGGCCGCGTGGTGCCCCTGCTCAGCCACGGCGACGTCTGTATGGATCCGAGCAGCCGC
AAGGTCACCAAGGACGGCAA

Downstream 100 bases:

>100_bases
ATCTGCCTGCGCGGCAGTGCGAGGGCACTACGAAACGCGGCTGACCAAACGACTGCGCAACCACGGGATGGCGCGGCCAG
TGCTCGGTGCGGCATGTACC

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MGGAERTRIPPAAGVDGTCRTRGHQGSAGRRHLWRPIRRGQQHDRGVCAPVAAQAGRCADLHRLWPGLHGRKDPGMKSLQ
ARMLAALAAIVLLSWSTSLWILVALVTQGHHSVFEQELNLLGDQLLATLPDALQHRFDTQTEPPDAATTPTPIGNPSSRM
SVKQTLIAVVLNTVQLGILGLLMWWAVRTSLGPLRALSGAIAQRTGLDTEPVPLAQAPDEIRPLIASFNTLLARVEQAVQ
AERDFVADAAHELRTPLSALHAYAEVALRAPTLDAKDAALRQLLETARRSNRLAEQLLDLARLDAGISSAAYHQVEMGEL
ISHVLDEFSVQANTRQMQLQVEASPCLVRCDVDAVGILIRNLVDNAIRYGRLHGKVEVSCGYCLRADVLHPFLQVSDDGP
GVPESAQAAIFERFYRVPGSAVQGSGIGLSLVAGIARLHGATIEAGDGNDGRGLCVRVVFAGDHPASAA

Sequences:

>Translated_469_residues
MGGAERTRIPPAAGVDGTCRTRGHQGSAGRRHLWRPIRRGQQHDRGVCAPVAAQAGRCADLHRLWPGLHGRKDPGMKSLQ
ARMLAALAAIVLLSWSTSLWILVALVTQGHHSVFEQELNLLGDQLLATLPDALQHRFDTQTEPPDAATTPTPIGNPSSRM
SVKQTLIAVVLNTVQLGILGLLMWWAVRTSLGPLRALSGAIAQRTGLDTEPVPLAQAPDEIRPLIASFNTLLARVEQAVQ
AERDFVADAAHELRTPLSALHAYAEVALRAPTLDAKDAALRQLLETARRSNRLAEQLLDLARLDAGISSAAYHQVEMGEL
ISHVLDEFSVQANTRQMQLQVEASPCLVRCDVDAVGILIRNLVDNAIRYGRLHGKVEVSCGYCLRADVLHPFLQVSDDGP
GVPESAQAAIFERFYRVPGSAVQGSGIGLSLVAGIARLHGATIEAGDGNDGRGLCVRVVFAGDHPASAA
>Mature_468_residues
GGAERTRIPPAAGVDGTCRTRGHQGSAGRRHLWRPIRRGQQHDRGVCAPVAAQAGRCADLHRLWPGLHGRKDPGMKSLQA
RMLAALAAIVLLSWSTSLWILVALVTQGHHSVFEQELNLLGDQLLATLPDALQHRFDTQTEPPDAATTPTPIGNPSSRMS
VKQTLIAVVLNTVQLGILGLLMWWAVRTSLGPLRALSGAIAQRTGLDTEPVPLAQAPDEIRPLIASFNTLLARVEQAVQA
ERDFVADAAHELRTPLSALHAYAEVALRAPTLDAKDAALRQLLETARRSNRLAEQLLDLARLDAGISSAAYHQVEMGELI
SHVLDEFSVQANTRQMQLQVEASPCLVRCDVDAVGILIRNLVDNAIRYGRLHGKVEVSCGYCLRADVLHPFLQVSDDGPG
VPESAQAAIFERFYRVPGSAVQGSGIGLSLVAGIARLHGATIEAGDGNDGRGLCVRVVFAGDHPASAA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=38.0782918149466, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790551, Length=264, Percent_Identity=32.1969696969697, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786783, Length=288, Percent_Identity=28.125, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=315, Percent_Identity=24.7619047619048, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790861, Length=313, Percent_Identity=26.517571884984, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=30.4721030042918, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=27.6150627615063, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=29.2682926829268, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=30.0469483568075, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082128, Length=255, Percent_Identity=28.2352941176471, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787374, Length=294, Percent_Identity=26.1904761904762, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=27.3469387755102, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=26.2096774193548, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=23.4513274336283, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=26.7241379310345, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50291; Mature: 50160

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGAERTRIPPAAGVDGTCRTRGHQGSAGRRHLWRPIRRGQQHDRGVCAPVAAQAGRCAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHH
LHRLWPGLHGRKDPGMKSLQARMLAALAAIVLLSWSTSLWILVALVTQGHHSVFEQELNL
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHH
LGDQLLATLPDALQHRFDTQTEPPDAATTPTPIGNPSSRMSVKQTLIAVVLNTVQLGILG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLMWWAVRTSLGPLRALSGAIAQRTGLDTEPVPLAQAPDEIRPLIASFNTLLARVEQAVQ
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AERDFVADAAHELRTPLSALHAYAEVALRAPTLDAKDAALRQLLETARRSNRLAEQLLDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLDAGISSAAYHQVEMGELISHVLDEFSVQANTRQMQLQVEASPCLVRCDVDAVGILIR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEECHHHHHHHHH
NLVDNAIRYGRLHGKVEVSCGYCLRADVLHPFLQVSDDGPGVPESAQAAIFERFYRVPGS
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHCCCC
AVQGSGIGLSLVAGIARLHGATIEAGDGNDGRGLCVRVVFAGDHPASAA
CCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
GGAERTRIPPAAGVDGTCRTRGHQGSAGRRHLWRPIRRGQQHDRGVCAPVAAQAGRCAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHH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CCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA