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The map label for this gene is msrB [H]

Identifier: 21244416

GI number: 21244416

Start: 4367833

End: 4368297

Strand: Direct

Name: msrB [H]

Synonym: XAC3691

Alternate gene names: 21244416

Gene position: 4367833-4368297 (Clockwise)

Preceding gene: 21244414

Following gene: 21244417

Centisome position: 84.39

GC content: 67.96

Gene sequence:

>465_bases
ATGAGCCAGTTCGATCTGACCCCTCCCTCCCCCGCCCAACGCGATGCCCTGATCGCCGGGCTCAGCGACGAGGAACAGCG
CGTGCTGCTGCACCATGGCACCGAGGCGCCGTTCTGCGGGGTGTTCCTGGACAACAAGCTGGACGGTGTCTACACCTGCC
GGCTGTGCGGCCTGCCGTTGTTCCGTTCCAGCGCCAAATTCGAGTCCGGCACCGGCTGGCCGAGCTTCTTTGCGCCTTAC
GACCCTGCCCATGTGCGCGAGATCCGCGACACCAGCTACGGCATGATCCGCACCGAAATCGTGTGCGCGCGCTGCGACAG
CCATCTGGGCCATGTGTTCCCGGACGGCCCGCCCCCCACTGGCGAGCGCCACTGCCTGAACTCGGTCTCGCTGGGCTTCA
CCGAAAACGGCCAGGCCCTGCCGAACCCCCTGCATCGCCGAGGCGCCGAGGCGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGGCTGTTGGCTGCGTCTCAACGGTTGAACCACCCCGACAATGCCCACATCACGGAAGCAGGCGCCGGCACCCCGCTGG
CGAGCGCATGCGAGAACCCC

Downstream 100 bases:

>100_bases
TGGCCCGCGTACCTGCGAGGACACGGCCATTGCAGTGCCTGGAGGTGCTCGACAACGCCTCCCTGCGCTTTTGTGCGCTG
AGGCCAGCACCGCTCACGGG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSQFDLTPPSPAQRDALIAGLSDEEQRVLLHHGTEAPFCGVFLDNKLDGVYTCRLCGLPLFRSSAKFESGTGWPSFFAPY
DPAHVREIRDTSYGMIRTEIVCARCDSHLGHVFPDGPPPTGERHCLNSVSLGFTENGQALPNPLHRRGAEAQAA

Sequences:

>Translated_154_residues
MSQFDLTPPSPAQRDALIAGLSDEEQRVLLHHGTEAPFCGVFLDNKLDGVYTCRLCGLPLFRSSAKFESGTGWPSFFAPY
DPAHVREIRDTSYGMIRTEIVCARCDSHLGHVFPDGPPPTGERHCLNSVSLGFTENGQALPNPLHRRGAEAQAA
>Mature_153_residues
SQFDLTPPSPAQRDALIAGLSDEEQRVLLHHGTEAPFCGVFLDNKLDGVYTCRLCGLPLFRSSAKFESGTGWPSFFAPYD
PAHVREIRDTSYGMIRTEIVCARCDSHLGHVFPDGPPPTGERHCLNSVSLGFTENGQALPNPLHRRGAEAQAA

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=47.6923076923077, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI301336164, Length=134, Percent_Identity=42.5373134328358, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI301336162, Length=134, Percent_Identity=42.5373134328358, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI73089054, Length=134, Percent_Identity=42.5373134328358, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI37620216, Length=131, Percent_Identity=43.5114503816794, Blast_Score=117, Evalue=5e-27,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=54.6875, Blast_Score=146, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17553450, Length=127, Percent_Identity=45.6692913385827, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115532676, Length=127, Percent_Identity=45.6692913385827, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=115, Percent_Identity=41.7391304347826, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=41.7322834645669, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24645799, Length=132, Percent_Identity=41.6666666666667, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45553335, Length=133, Percent_Identity=41.3533834586466, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356369, Length=133, Percent_Identity=41.3533834586466, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=39.5522388059701, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24645801, Length=144, Percent_Identity=38.1944444444444, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24645804, Length=144, Percent_Identity=38.1944444444444, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16822; Mature: 16691

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFDLTPPSPAQRDALIAGLSDEEQRVLLHHGTEAPFCGVFLDNKLDGVYTCRLCGLPL
CCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCHH
FRSSAKFESGTGWPSFFAPYDPAHVREIRDTSYGMIRTEIVCARCDSHLGHVFPDGPPPT
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GERHCLNSVSLGFTENGQALPNPLHRRGAEAQAA
CCHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
SQFDLTPPSPAQRDALIAGLSDEEQRVLLHHGTEAPFCGVFLDNKLDGVYTCRLCGLPL
CCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCEEEEEECCCHH
FRSSAKFESGTGWPSFFAPYDPAHVREIRDTSYGMIRTEIVCARCDSHLGHVFPDGPPPT
HCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GERHCLNSVSLGFTENGQALPNPLHRRGAEAQAA
CCHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA