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The map label for this gene is recG [H]

Identifier: 21244116

GI number: 21244116

Start: 3997178

End: 3999331

Strand: Reverse

Name: recG [H]

Synonym: XAC3391

Alternate gene names: 21244116

Gene position: 3999331-3997178 (Counterclockwise)

Preceding gene: 21244117

Following gene: 21244115

Centisome position: 77.27

GC content: 67.04

Gene sequence:

>2154_bases
GTGTCGCGCACGCGCGTCGTCACACCGAGCCTGGCCGTCGCCGGCCAGGCTCGGCTGTCCAGCCTGCCCGGTGTCGGCCC
GAAAGTGGCCGACAGGTTCGCTGCGCGCGGCATCCTGAGCGTGCAGGACCTGTGGCTGCATCTGCCGCTGCGTTACGAAG
ACCGCACGCGCTTGACCACCATCGCGCAGCTGCAAGGTGGCGTGCCGGCCCAGATCGAAGGGCGTGTGGACGCGGTGGAA
CGTGGCTTCCGTTTCCGGCCGGTGCTGCGCGTGGCAGTGTCCGACGCGTCGTATGGCACGCTGGTGCTGCGCTTCTTTCA
TTTCCGCGCCGCACAGGTGGCGCAGTTCGCCGTCGGCACACGTGTGCGGGTGTTCGGCACACCCAAGCCCGGCCAGCACG
GCTGGGAGATCGTGCACCCCAGTTACCGCGTGCTCGCGCCGGACGAAGATGCCGGGTTGGGCGACAGTCTGGATCCGGTG
TATCCGGTGCTCGAAGGCGTTGGCCCGGCGACGTTGCGCAAGCTCATCGGTCAGGCGCTGGAGCGTCTGCCGCCCGAAAG
TGCGCTGGAATTGTTGCCACCGCATTGGCTGCAGGACGAGCGACTGCCCTCATTGCGCGCGGCGTTGCTCACCATGCATC
GCCCGCCGGTCGGTACTGATCCACAGCAACTGCTCGCCGGAGGCCACCCGGCCCAGCAGCGCCTGGCGATCGAGGAATTG
CTGGCACACCAACTCAGCCTGCGCCGGCAACGCATCGCATTGCAACGTCTGCACGCGCCCAGCCTGCCCGGCAACGGCAC
ATTGGTGCAGCAATTGCGCAAGGCGCTGCCGTTCCAGCTGACCGGTGCGCAACAACGGGTGTTCGAGCAGATTGCGCATG
ACCTTGCGCAGCCCTCGCCGATGCTTCGGCTGGTACAGGGCGATGTCGGCAGCGGCAAGACCGTGGTGGCCGCACTGGCG
GCAATGTTGGCGGTGGAGCAGGGCAAACAGGTCGCACTTGCCGCGCCCACCGAATTGCTGGCCGAGCAGCACCTCACCAA
TCTGCGTGGCTGGTTGGAACCCTTGGGCATCCGCATCGTCTGGCTGGCTGGCAAGGTCACCGGCAAGGCGCGCGCTGCAG
CGATGGCCGAGGTCGCCTCCGGTCAGGCGCAGGTCGTGGTCGGCACGCATGCGTTGATGCAGGAAGCAGTGGTCTTCCAC
GATCTGGCGTTGGCCATCATCGACGAGCAACACCGCTTCGGCGTGCATCAGCGCCTTGCGCTGCGCGACAAGGGGGCGGC
GGCGGGCAGCGTGCCGCATCAACTGGTGATGACCGCCACGCCCATCCCGCGCACATTGGCGATGTCTGCTTACGCAGATC
TGGATGTTTCGGCCATCGACGAATTGCCGCCTGGCCGCACGCCGGTGCAGACGATCGTGCTGAGCGCGGAGCGCCGGCCC
GAGTTGGTCGAACGTATCCGCGCCGCCTGTGCCGAAGGGCGGCAGGCGTATTGGGTGTGCACGCTGATCGAAGAAAGCGA
AGAGCCCGGGAAAGGCGCGCAAGGCCAGCAAGGCGGCCCGCCACGCATCGAAGCGCAGGCGGCCGAAGTCACCTTCGAGA
CCTTGTCGGCGCAGTTGCCGGGCGTGCGGGTGGCGCTGGTGCACGGCCGCATGAAGCCGGCCGAGAAGCAGAAGGCCATG
CTGGATTTCAAGCAAGGCCGTAGCGACCTGTTGGTGGCCACCACCGTGATCGAAGTCGGCGTGGACGTGCCCAATGCATC
GTTGATGATCATCGAAAATGCCGAGCGGCTTGGCCTGGCCCAGTTGCACCAGTTGCGCGGCCGGGTCGGTCGCGGTGCGG
CCGCTTCCAGTTGCGTGTTGCTGTACCAGGCGCCGTTGTCGATGATGGCGCGTCAGCGTCTGGAGACCATGCGCCAGACC
AACGACGGTTTCGTGATCGCGGAGAAGGATCTCCAATTGCGTGGCCCGGGCGAATTGCTGGGCACCCGGCAAACCGGTCT
GGCCAGTTTCCGCATCGCCGATCTGGCGCGCGATGCAGGGCTGTTGCCGCGCGTGCAGTTACTGGCCGAGCGGCTGCTGG
ACGAAGCGCCAGACATTGCCGACCGCGTGGTCGAACGCTGGATCGGCGGCGCGGTGCGTTACGCGGCCGCGTGA

Upstream 100 bases:

>100_bases
CGGCGCGTTCGACCATAGAAGTCTCCGGCCTGCCCAAGGGTGCCGGCTTCGAGGTCGATGCAGTGATGGTGATCGAGTGA
TCCTGCACCGCTGATCGGCC

Downstream 100 bases:

>100_bases
GCGGCGGGAATCGGATTGGGGAATCTTAAAAGCAAAGGCTGCTGCCCCTGTGCAACCTGGGCGTTCGCGTGACCGGCCGA
TCCTTGCGAAGATGCGGCAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADRFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVDAVE
RGFRFRPVLRVAVSDASYGTLVLRFFHFRAAQVAQFAVGTRVRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPV
YPVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPSPMLRLVQGDVGSGKTVVAALA
AMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAAMAEVASGQAQVVVGTHALMQEAVVFH
DLALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
ELVERIRAACAEGRQAYWVCTLIEESEEPGKGAQGQQGGPPRIEAQAAEVTFETLSAQLPGVRVALVHGRMKPAEKQKAM
LDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQT
NDGFVIAEKDLQLRGPGELLGTRQTGLASFRIADLARDAGLLPRVQLLAERLLDEAPDIADRVVERWIGGAVRYAAA

Sequences:

>Translated_717_residues
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADRFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVDAVE
RGFRFRPVLRVAVSDASYGTLVLRFFHFRAAQVAQFAVGTRVRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPV
YPVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPSPMLRLVQGDVGSGKTVVAALA
AMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAAMAEVASGQAQVVVGTHALMQEAVVFH
DLALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
ELVERIRAACAEGRQAYWVCTLIEESEEPGKGAQGQQGGPPRIEAQAAEVTFETLSAQLPGVRVALVHGRMKPAEKQKAM
LDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQT
NDGFVIAEKDLQLRGPGELLGTRQTGLASFRIADLARDAGLLPRVQLLAERLLDEAPDIADRVVERWIGGAVRYAAA
>Mature_716_residues
SRTRVVTPSLAVAGQARLSSLPGVGPKVADRFAARGILSVQDLWLHLPLRYEDRTRLTTIAQLQGGVPAQIEGRVDAVER
GFRFRPVLRVAVSDASYGTLVLRFFHFRAAQVAQFAVGTRVRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVY
PVLEGVGPATLRKLIGQALERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEELL
AHQLSLRRQRIALQRLHAPSLPGNGTLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPSPMLRLVQGDVGSGKTVVAALAA
MLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIVWLAGKVTGKARAAAMAEVASGQAQVVVGTHALMQEAVVFHD
LALAIIDEQHRFGVHQRLALRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRPE
LVERIRAACAEGRQAYWVCTLIEESEEPGKGAQGQQGGPPRIEAQAAEVTFETLSAQLPGVRVALVHGRMKPAEKQKAML
DFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLAQLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTN
DGFVIAEKDLQLRGPGELLGTRQTGLASFRIADLARDAGLLPRVQLLAERLLDEAPDIADRVVERWIGGAVRYAAA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=700, Percent_Identity=58, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=402, Percent_Identity=38.5572139303483, Blast_Score=248, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77594; Mature: 77463

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTRVVTPSLAVAGQARLSSLPGVGPKVADRFAARGILSVQDLWLHLPLRYEDRTRLTT
CCCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQIEGRVDAVERGFRFRPVLRVAVSDASYGTLVLRFFHFRAAQVAQFAVGT
HHHHCCCCCCEECCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
RVRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCCH
MLRLVQGDVGSGKTVVAALAAMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEE
WLAGKVTGKARAAAMAEVASGQAQVVVGTHALMQEAVVFHDLALAIIDEQHRFGVHQRLA
EEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
LRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCCCH
ELVERIRAACAEGRQAYWVCTLIEESEEPGKGAQGQQGGPPRIEAQAAEVTFETLSAQLP
HHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GVRVALVHGRMKPAEKQKAMLDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLA
CEEEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHH
QLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTNDGFVIAEKDLQLRGPGELL
HHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCHHHH
GTRQTGLASFRIADLARDAGLLPRVQLLAERLLDEAPDIADRVVERWIGGAVRYAAA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
SRTRVVTPSLAVAGQARLSSLPGVGPKVADRFAARGILSVQDLWLHLPLRYEDRTRLTT
CCCEECCCCHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHEECCCCCCCCHHHHH
IAQLQGGVPAQIEGRVDAVERGFRFRPVLRVAVSDASYGTLVLRFFHFRAAQVAQFAVGT
HHHHCCCCCCEECCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
RVRVFGTPKPGQHGWEIVHPSYRVLAPDEDAGLGDSLDPVYPVLEGVGPATLRKLIGQAL
EEEEEECCCCCCCCCEEECCCEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHH
ERLPPESALELLPPHWLQDERLPSLRAALLTMHRPPVGTDPQQLLAGGHPAQQRLAIEEL
HHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHHHHHH
LAHQLSLRRQRIALQRLHAPSLPGNGTLVQQLRKALPFQLTGAQQRVFEQIAHDLAQPSP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCCH
MLRLVQGDVGSGKTVVAALAAMLAVEQGKQVALAAPTELLAEQHLTNLRGWLEPLGIRIV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEE
WLAGKVTGKARAAAMAEVASGQAQVVVGTHALMQEAVVFHDLALAIIDEQHRFGVHQRLA
EEECCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
LRDKGAAAGSVPHQLVMTATPIPRTLAMSAYADLDVSAIDELPPGRTPVQTIVLSAERRP
HHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCCCH
ELVERIRAACAEGRQAYWVCTLIEESEEPGKGAQGQQGGPPRIEAQAAEVTFETLSAQLP
HHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
GVRVALVHGRMKPAEKQKAMLDFKQGRSDLLVATTVIEVGVDVPNASLMIIENAERLGLA
CEEEEEEECCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEEEECCHHCCHH
QLHQLRGRVGRGAAASSCVLLYQAPLSMMARQRLETMRQTNDGFVIAEKDLQLRGPGELL
HHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCHHHH
GTRQTGLASFRIADLARDAGLLPRVQLLAERLLDEAPDIADRVVERWIGGAVRYAAA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]