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The map label for this gene is pilQ [H]

Identifier: 21244106

GI number: 21244106

Start: 3985410

End: 3987311

Strand: Reverse

Name: pilQ [H]

Synonym: XAC3381

Alternate gene names: 21244106

Gene position: 3987311-3985410 (Counterclockwise)

Preceding gene: 21244107

Following gene: 21244105

Centisome position: 77.04

GC content: 60.2

Gene sequence:

>1902_bases
ATGACGTTTTCCAATGCCCAGCGGCTGCGTCCGGTACGACGCCACGCGATCTTCCAGGCCTGCGCGTTGGGGTTCGCGCT
GGCGCTGGCGAGCGGCAGCGCATTCGCCGCCGCGGCGCTGACTCAGCCCGCGCAGGATCCGGCCAAGGTCGCTCCGGCCA
GCCTGGCGGTGTCCAAAATCGATTTCAAGCGCGGCGAAGACGGCGCTGGCCGTCTGATCCTGCAGTTCGACGGCCAGGGC
GCCAGCCCGGACCTGCGGACGCAGGGCGACAACGTGCTGGTGGACATCAGCAATGCCAAGCTACCTGCCGAGCTGCAACG
CCCGCTCAATGTCACCGACTTCGCCACGCCGGTGCAGCGCGTTGAAGTGAAGCCGTCCGGTTCCGGTTCGCAGCTGGTGC
TATCGACCAAGGGTGCCTTCGATTCGCTGGCCTACCAGACCGGCAACGAATACGTGGTGGAAATCACCCCGCGCAAGGGC
CAGCCGGCGGTTGGCGGTGTGAGCCCGGCGGCGGTCACGCAGGCTGCCGCGCAGATCGCCGCGCGCGGCTATAGCGGCCG
CCCGGTGACGTTCAACTTCCAGGACGTGCCGGTGCGCACCGTGCTGCAGCTGATCGCCGAAGAGTCCAACCTCAACATCG
TCGCGTCCGACACCGTGCAGGGCAATGTCACGCTGCGCCTGATGAATGTGCCGTGGGACCAGGCGTTGGACATCGTGCTG
CGTGCCAAGGGCCTGGACAAGCGACGCGATGGCGGCGTGGTGTGGGTCGCCCCGCAACCGGAGCTGGCCAAGTTCGAGCA
GGACAAGGAAGACGCCCGCATCGCGATCGAGAACCGCGAGGACTTGATCACCGATTATGTGCAGATCAACTACCACAACG
CTGCGGTGATCTTCAAAGCGTTGACCGAAGCGAAAGGCATCGGCGGTGGTGGTGGCGGTCAGGGCGGTGGTCAAGGTGGC
GCAGGGCAGCAGGACAACGGGTTCCTGTCGCCGCGCGGTCGCCTGGTGGCTGACGAACGCACCAACACCTTGATGATCAG
CGATATCCCGAAGAAGGTCGCGCAGATGCGCGAACTGATCTCGCATATCGACCGCCCGGTGGATCAGGTGTTGATCGAGA
GCCGTATCGTGATTGCGACCGATACGTTTGCCCGCGACTTGGGTGCGCGCTTCGGTATCGCAGGTCGGCGGCAGTACGGC
GACAACACGGCGGTGATCAGCGGTAGTTCCACCAACAATGTTTCTGTCATAAACGATGGCTTGCATAACGTCCCGTCCGG
ACTGAACTTCAATCTTCCTGCCGGAACATTCACCACCAATACGGCAGGCTCGATTGCTTATACACTGCTTGGACGCAATT
TCGCGTTGGACATGGAACTATCGGCAATGCAGGAAGAGGGACGTGGTGAGGTCGTCTCCAACCCGCGCATCGTTACTGCC
AACCAGCGCGAAGGCGTGATCAAGCAGGGTCGTGAGATTGGATATGTGACGATAAGTGGCGGTGGTACTGGTGGCCAATC
GCAGGCGAACGTACAGTTCAAGGAAGTGCTCTTGGAACTTAAGGTTACGCCCACTATTACAAATGACAATCGTGTTTTCT
TGAACATGAATGTAAAGAAGGACGAGGTTGCACGATTTATTAATTTGCCACTGTATGGAACGGTGCCTGAAATCAATCGC
CGCGAAGTCAATACCGCTGTGCTTGTCGGTGATGGCGAGACGGTGGTGATCGGCGGTGTCTACGAATTCAACGATCGCGA
GAGCGTGGCCAAGGTTCCGTTCTTGGGCGACATTCCTTTCCTTGGCAATCTGTTCAAAAAGCGTGGGCGCAGCAAGGAGA
AGGCTGAATTGCTGGTCTTCGTGACGCCGAAGGTGTTGCGTGTTGCTGGTGCTACTAAATAA

Upstream 100 bases:

>100_bases
ATCGAGCTGATTGAACTTGTGCCGGACGGTGCGGGTGGATGGCTTGAACGGCCGGCCGCACTCGCATTGGATGATCAATA
AAGTGATAGGGGATAGCACG

Downstream 100 bases:

>100_bases
ATAGTCCTGAATTTTTGATGGGTAGTAACTTGATTCATATTTCATCAAAGAGGGAATTTTTGTGAAAGCATTATTTAGTG
TAAAAAATTATTTAGGTGCA

Product: fimbrial assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGGQGG
AGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGIAGRRQYG
DNTAVISGSSTNNVSVINDGLHNVPSGLNFNLPAGTFTTNTAGSIAYTLLGRNFALDMELSAMQEEGRGEVVSNPRIVTA
NQREGVIKQGREIGYVTISGGGTGGQSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVARFINLPLYGTVPEINR
REVNTAVLVGDGETVVIGGVYEFNDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVAGATK

Sequences:

>Translated_633_residues
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQG
ASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKG
QPAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGGQGG
AGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGIAGRRQYG
DNTAVISGSSTNNVSVINDGLHNVPSGLNFNLPAGTFTTNTAGSIAYTLLGRNFALDMELSAMQEEGRGEVVSNPRIVTA
NQREGVIKQGREIGYVTISGGGTGGQSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVARFINLPLYGTVPEINR
REVNTAVLVGDGETVVIGGVYEFNDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVAGATK
>Mature_632_residues
TFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKIDFKRGEDGAGRLILQFDGQGA
SPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQRVEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQ
PAVGGVSPAAVTQAAAQIAARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVLR
AKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKALTEAKGIGGGGGGQGGGQGGA
GQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELISHIDRPVDQVLIESRIVIATDTFARDLGARFGIAGRRQYGD
NTAVISGSSTNNVSVINDGLHNVPSGLNFNLPAGTFTTNTAGSIAYTLLGRNFALDMELSAMQEEGRGEVVSNPRIVTAN
QREGVIKQGREIGYVTISGGGTGGQSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKKDEVARFINLPLYGTVPEINRR
EVNTAVLVGDGETVVIGGVYEFNDRESVAKVPFLGDIPFLGNLFKKRGRSKEKAELLVFVTPKVLRVAGATK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=446, Percent_Identity=30.0448430493274, Blast_Score=202, Evalue=8e-53,
Organism=Escherichia coli, GI87082242, Length=392, Percent_Identity=26.0204081632653, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 67726; Mature: 67594

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCCHHHEEEEE
DFKRGEDGAGRLILQFDGQGASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSPAAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
EECCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGQGGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELI
HHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHH
SHIDRPVDQVLIESRIVIATDTFARDLGARFGIAGRRQYGDNTAVISGSSTNNVSVINDG
HHHCCCHHHHHHHCEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEECC
LHNVPSGLNFNLPAGTFTTNTAGSIAYTLLGRNFALDMELSAMQEEGRGEVVSNPRIVTA
HHHCCCCCEECCCCCCEECCCCCCEEEEEECCCEEEEEEHHHHHHCCCCCEECCCEEEEC
NQREGVIKQGREIGYVTISGGGTGGQSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKK
CCCCCHHHCCCEEEEEEEECCCCCCCCCCCHHHHHEEEEEEEEEEEECCCEEEEEECCCH
DEVARFINLPLYGTVPEINRREVNTAVLVGDGETVVIGGVYEFNDRESVAKVPFLGDIPF
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCH
LGNLFKKRGRSKEKAELLVFVTPKVLRVAGATK
HHHHHHHHCCCCCCCEEEEEECCHHHHHCCCCC
>Mature Secondary Structure 
TFSNAQRLRPVRRHAIFQACALGFALALASGSAFAAAALTQPAQDPAKVAPASLAVSKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCCHHHEEEEE
DFKRGEDGAGRLILQFDGQGASPDLRTQGDNVLVDISNAKLPAELQRPLNVTDFATPVQR
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHCCCCCE
VEVKPSGSGSQLVLSTKGAFDSLAYQTGNEYVVEITPRKGQPAVGGVSPAAVTQAAAQIA
EEECCCCCCCEEEEEECCCHHHHHEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
ARGYSGRPVTFNFQDVPVRTVLQLIAEESNLNIVASDTVQGNVTLRLMNVPWDQALDIVL
HCCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCEECEEEEEEEECCHHHHHHHHH
RAKGLDKRRDGGVVWVAPQPELAKFEQDKEDARIAIENREDLITDYVQINYHNAAVIFKA
EECCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEECCHHHEEEEEEEEECCHHHHHHH
LTEAKGIGGGGGGQGGGQGGAGQQDNGFLSPRGRLVADERTNTLMISDIPKKVAQMRELI
HHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHH
SHIDRPVDQVLIESRIVIATDTFARDLGARFGIAGRRQYGDNTAVISGSSTNNVSVINDG
HHHCCCHHHHHHHCEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEECC
LHNVPSGLNFNLPAGTFTTNTAGSIAYTLLGRNFALDMELSAMQEEGRGEVVSNPRIVTA
HHHCCCCCEECCCCCCEECCCCCCEEEEEECCCEEEEEEHHHHHHCCCCCEECCCEEEEC
NQREGVIKQGREIGYVTISGGGTGGQSQANVQFKEVLLELKVTPTITNDNRVFLNMNVKK
CCCCCHHHCCCEEEEEEEECCCCCCCCCCCHHHHHEEEEEEEEEEEECCCEEEEEECCCH
DEVARFINLPLYGTVPEINRREVNTAVLVGDGETVVIGGVYEFNDRESVAKVPFLGDIPF
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCH
LGNLFKKRGRSKEKAELLVFVTPKVLRVAGATK
HHHHHHHHCCCCCCCEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]