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The map label for this gene is adrA [H]

Identifier: 21242238

GI number: 21242238

Start: 1718512

End: 1719486

Strand: Reverse

Name: adrA [H]

Synonym: XAC1486

Alternate gene names: 21242238

Gene position: 1719486-1718512 (Counterclockwise)

Preceding gene: 21242240

Following gene: 21242232

Centisome position: 33.22

GC content: 65.33

Gene sequence:

>975_bases
GTGATCCTCCACCTGCGGCGGGATTTTCGACTCGGCATCGTCAAGATGCTCGGGCCAATCACCGCGCTGTTGCTTTGCCT
CTATGCGGTGTACCTGGCCATGACCGGTCAGGTAGTTGCGTGCCTGGTCACCGCCGCTCTGGGCGTGCTCGCGGTATGGC
GCGGCTGGCAGATGCGCAGTGCCGAAGACACCGGCGCCGGCGGCGTGTGGCTGGCGTCGATCAACGTCGGCGGGTGCCTG
GTGGCGTGCTGGACCGGTGGCGACGGCGCCCTGCCCTGGCTGTTCCCGGTGCTGGCCACCAATTATTTCCTGTGCGGGCC
GCGACGCGCGGTGTTGTTGAGCTTGCCGCTGCTGGCCGCCTTGTTGTTCTTGCCAGGCTTGATTACCAGCCCTGGCCAGG
GCGTGTCGACGATCGTGGTGACGCTGGTGACGCTGGCGGTGGGCTACGCGTTTTCGCTGCGGATGCAGGACGACCGCGTG
CACCTGGAAGAACTGGCCTCGCTGGATGCGCTGACCGGCTTGCCCAACCGTCGCATGCTGGAACGTGCGCTGACCCACCA
GATCGATCAACGCCAACCGCACGACCGGCTCAACAGCCTGATCATCCTGGATCTGGATCACTTCAAGGAGGTCAACGATC
TGTACGGGCATGCCGCCGGCGATGCGGCGCTCTCGGATCTGGCTACCATCCTGCGCTTCGAAGTACGCGAACCGCACCAG
GTCTTCCGTTTTGGCGGCGAAGAATTCGTGGTGCTGCTGCGTGCCGGCTCGCTGGCCGAACTGGAAGCGGCCACCGAACG
CTTGCGCAAGGTGATACGCAACGGCTTGCGCGGACCCGGCGGGCGCATCACCGTCTCGTTGGGCGCGGCGCGCCACGATG
GCGAAACGCATTGGCAGGACTGGTTTTCGCGTGCCGATGCAGCGCTGTATCTGGCCAAGAACGGCGGACGCGACAGCGTG
CGGGTTGCCGAATAA

Upstream 100 bases:

>100_bases
CTGCAACGCTTCACTTTCCTACCCGTTGCGGCCATGAAGGCACGCTCAACTTTGACCGCACTCCGCCGATAATGATGCCG
ACTCCTATCGAACCTTCCCT

Downstream 100 bases:

>100_bases
GCGCCTGGCGGCATGTAAGCGTCCGGGTCTGCGTAGGCACACGCACCTGGCGGATGGGTTACGCATTGGTCGCGAATGCG
ATGGGGTTGACGAAAGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MILHLRRDFRLGIVKMLGPITALLLCLYAVYLAMTGQVVACLVTAALGVLAVWRGWQMRSAEDTGAGGVWLASINVGGCL
VACWTGGDGALPWLFPVLATNYFLCGPRRAVLLSLPLLAALLFLPGLITSPGQGVSTIVVTLVTLAVGYAFSLRMQDDRV
HLEELASLDALTGLPNRRMLERALTHQIDQRQPHDRLNSLIILDLDHFKEVNDLYGHAAGDAALSDLATILRFEVREPHQ
VFRFGGEEFVVLLRAGSLAELEAATERLRKVIRNGLRGPGGRITVSLGAARHDGETHWQDWFSRADAALYLAKNGGRDSV
RVAE

Sequences:

>Translated_324_residues
MILHLRRDFRLGIVKMLGPITALLLCLYAVYLAMTGQVVACLVTAALGVLAVWRGWQMRSAEDTGAGGVWLASINVGGCL
VACWTGGDGALPWLFPVLATNYFLCGPRRAVLLSLPLLAALLFLPGLITSPGQGVSTIVVTLVTLAVGYAFSLRMQDDRV
HLEELASLDALTGLPNRRMLERALTHQIDQRQPHDRLNSLIILDLDHFKEVNDLYGHAAGDAALSDLATILRFEVREPHQ
VFRFGGEEFVVLLRAGSLAELEAATERLRKVIRNGLRGPGGRITVSLGAARHDGETHWQDWFSRADAALYLAKNGGRDSV
RVAE
>Mature_324_residues
MILHLRRDFRLGIVKMLGPITALLLCLYAVYLAMTGQVVACLVTAALGVLAVWRGWQMRSAEDTGAGGVWLASINVGGCL
VACWTGGDGALPWLFPVLATNYFLCGPRRAVLLSLPLLAALLFLPGLITSPGQGVSTIVVTLVTLAVGYAFSLRMQDDRV
HLEELASLDALTGLPNRRMLERALTHQIDQRQPHDRLNSLIILDLDHFKEVNDLYGHAAGDAALSDLATILRFEVREPHQ
VFRFGGEEFVVLLRAGSLAELEAATERLRKVIRNGLRGPGGRITVSLGAARHDGETHWQDWFSRADAALYLAKNGGRDSV
RVAE

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=184, Percent_Identity=34.7826086956522, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=42.1686746987952, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787816, Length=174, Percent_Identity=36.7816091954023, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=35.2201257861635, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787262, Length=323, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=37.3417721518987, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788381, Length=163, Percent_Identity=35.5828220858896, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787541, Length=157, Percent_Identity=35.031847133758, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=147, Percent_Identity=27.891156462585, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87081977, Length=163, Percent_Identity=31.9018404907975, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787802, Length=307, Percent_Identity=28.0130293159609, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=28.2051282051282, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081921, Length=192, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 35322; Mature: 35322

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILHLRRDFRLGIVKMLGPITALLLCLYAVYLAMTGQVVACLVTAALGVLAVWRGWQMRS
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AEDTGAGGVWLASINVGGCLVACWTGGDGALPWLFPVLATNYFLCGPRRAVLLSLPLLAA
CCCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHH
LLFLPGLITSPGQGVSTIVVTLVTLAVGYAFSLRMQDDRVHLEELASLDALTGLPNRRML
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCHHHH
ERALTHQIDQRQPHDRLNSLIILDLDHFKEVNDLYGHAAGDAALSDLATILRFEVREPHQ
HHHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHH
VFRFGGEEFVVLLRAGSLAELEAATERLRKVIRNGLRGPGGRITVSLGAARHDGETHWQD
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHH
WFSRADAALYLAKNGGRDSVRVAE
HHHHCCEEEEEECCCCCCCCEECC
>Mature Secondary Structure
MILHLRRDFRLGIVKMLGPITALLLCLYAVYLAMTGQVVACLVTAALGVLAVWRGWQMRS
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AEDTGAGGVWLASINVGGCLVACWTGGDGALPWLFPVLATNYFLCGPRRAVLLSLPLLAA
CCCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHH
LLFLPGLITSPGQGVSTIVVTLVTLAVGYAFSLRMQDDRVHLEELASLDALTGLPNRRML
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCHHHH
ERALTHQIDQRQPHDRLNSLIILDLDHFKEVNDLYGHAAGDAALSDLATILRFEVREPHQ
HHHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHH
VFRFGGEEFVVLLRAGSLAELEAATERLRKVIRNGLRGPGGRITVSLGAARHDGETHWQD
HHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHH
WFSRADAALYLAKNGGRDSVRVAE
HHHHCCEEEEEECCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]