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The map label for this gene is murG

Identifier: 21241549

GI number: 21241549

Start: 923870

End: 925150

Strand: Direct

Name: murG

Synonym: XAC0779

Alternate gene names: 21241549

Gene position: 923870-925150 (Clockwise)

Preceding gene: 21241548

Following gene: 21241550

Centisome position: 17.85

GC content: 67.84

Gene sequence:

>1281_bases
GTGAGCGTTTCTGCCAATGCCGCGCAAGCGCACGCACAGCCATCTGCGGTGCTGCGGCCGGTCATGATTCTGGCCGGCGG
CACCGGCGGGCACATCTTCCCGGGCTTGGCCGTGGCCAAGGTGCTGCGCGCGCGGGGCGTGCCGGTGACCTGGTTGGGCG
CCGATGGCGCCATGGAAACCCGCCTGGTGCCGCAGCACGATATTCCCATCGATACGCTGGCCATCAGCGGCTTGCGCGGC
AAGGGCGTGGTGAAGTTGCTCGGTGCGCCGGTGCGGGTGATGCGCGCGGTGCGCGCTGCCGGCTTCGTGCTGCGCAAGCG
CCAGCCGCGTGCGGTGATCAGCTTTGGCGGCTTTGCGGCCGGCCCGGGCGGCCTGGCCGCGCGCCTGCTCGGTGCGCCAT
TGCTGGTGCACGAACAGAATCGCGCACCCGGCATGACCAACAAGGTGTTGTCGCGTTTCGCGCGCCGCGTGCTGACCGGT
TTTCCGGGCAGCTTCGTTGGCGAAGAAGCGGTGGGCAACCCGGTGCGCGCGGAAATCGCGGCATTGCCTGCGCCGGCCGA
TCGTTTGTTCGGTCGCACCGGCCCGGTACGCGTGCTGGTACTAGGCGGCAGCCAGGGCGCGCGCGTGTTGAATCAGGCGC
TGCCGGCTGCGCTGGTCGCACTCGGCCATTCTGAGGTCGAGGTGCGCCATCAGTGCGGCGAAAAGCTGCGCGCCGAAGCC
GAAGCGGCCTATGCACAGGCAGGCGTCAACGCCAGCGTCGAACCCTTCATTGCCGACATGGCCGCTGCCTATGCCTGGGC
AGATCTGGTGGTATGCCGCGCCGGCGCGTCCACCCTGGCCGAACTGTGCGCCGCCGGTGTCGGCAGCGTGCTGGTGCCGT
TTGCCGCCGCCGTCGACGATCATCAAACCCGCAATGCCGAATACCTGGTCGGCGCCAACGCCGCCGTGCTGCTCAAGCAG
GACGACAGCCTGCCAGTGCGCTTGCAGCAGGTACTGCAGACCCTGCTCGCCGACCCGGCACGTCGCCTCTCAATGGCCAA
CGCTGCCCGCACCCTGGCCAAACCGGACGCCGCCGAGCGCATCGCCGACATCATTCTTCAAGAGGCAGGGAATGGTCCAT
CGGGAATGGGGAATGGACACAGCTCAGAACAACCGCAGGAACGCACATTGATGCACGCAGACAAGCGCACCGACCAAGTT
TCCGTCGCCGCTGGCGCTCAGCTCCACACCATTCCCGATTCCCGATTCCCGATTCGCACCTCCACTGGAGGTGCCCGGTG
A

Upstream 100 bases:

>100_bases
CCGCATCGGTTGGCGCCGCCTACGTAGCGCCGGCGTCGGCCATCCTGCGCGGCACCAGCCGCATGCAACCGCGTGTGGAA
CCGACGTTCGGGAGGATTGC

Downstream 100 bases:

>100_bases
TCCGCCGTCTGCAAGACAGTGGCGATCTGGTGCGGGCGTTCCCGCGCGTGCATTTCGTCGGCATCGGCGGTACCGGCATG
AGCGGCATTGCCGAGGTGAT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSVSANAAQAHAQPSAVLRPVMILAGGTGGHIFPGLAVAKVLRARGVPVTWLGADGAMETRLVPQHDIPIDTLAISGLRG
KGVVKLLGAPVRVMRAVRAAGFVLRKRQPRAVISFGGFAAGPGGLAARLLGAPLLVHEQNRAPGMTNKVLSRFARRVLTG
FPGSFVGEEAVGNPVRAEIAALPAPADRLFGRTGPVRVLVLGGSQGARVLNQALPAALVALGHSEVEVRHQCGEKLRAEA
EAAYAQAGVNASVEPFIADMAAAYAWADLVVCRAGASTLAELCAAGVGSVLVPFAAAVDDHQTRNAEYLVGANAAVLLKQ
DDSLPVRLQQVLQTLLADPARRLSMANAARTLAKPDAAERIADIILQEAGNGPSGMGNGHSSEQPQERTLMHADKRTDQV
SVAAGAQLHTIPDSRFPIRTSTGGAR

Sequences:

>Translated_426_residues
MSVSANAAQAHAQPSAVLRPVMILAGGTGGHIFPGLAVAKVLRARGVPVTWLGADGAMETRLVPQHDIPIDTLAISGLRG
KGVVKLLGAPVRVMRAVRAAGFVLRKRQPRAVISFGGFAAGPGGLAARLLGAPLLVHEQNRAPGMTNKVLSRFARRVLTG
FPGSFVGEEAVGNPVRAEIAALPAPADRLFGRTGPVRVLVLGGSQGARVLNQALPAALVALGHSEVEVRHQCGEKLRAEA
EAAYAQAGVNASVEPFIADMAAAYAWADLVVCRAGASTLAELCAAGVGSVLVPFAAAVDDHQTRNAEYLVGANAAVLLKQ
DDSLPVRLQQVLQTLLADPARRLSMANAARTLAKPDAAERIADIILQEAGNGPSGMGNGHSSEQPQERTLMHADKRTDQV
SVAAGAQLHTIPDSRFPIRTSTGGAR
>Mature_425_residues
SVSANAAQAHAQPSAVLRPVMILAGGTGGHIFPGLAVAKVLRARGVPVTWLGADGAMETRLVPQHDIPIDTLAISGLRGK
GVVKLLGAPVRVMRAVRAAGFVLRKRQPRAVISFGGFAAGPGGLAARLLGAPLLVHEQNRAPGMTNKVLSRFARRVLTGF
PGSFVGEEAVGNPVRAEIAALPAPADRLFGRTGPVRVLVLGGSQGARVLNQALPAALVALGHSEVEVRHQCGEKLRAEAE
AAYAQAGVNASVEPFIADMAAAYAWADLVVCRAGASTLAELCAAGVGSVLVPFAAAVDDHQTRNAEYLVGANAAVLLKQD
DSLPVRLQQVLQTLLADPARRLSMANAARTLAKPDAAERIADIILQEAGNGPSGMGNGHSSEQPQERTLMHADKRTDQVS
VAAGAQLHTIPDSRFPIRTSTGGAR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=346, Percent_Identity=49.7109826589595, Blast_Score=308, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_XANAC (Q8PPA8)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641131.1
- ProteinModelPortal:   Q8PPA8
- SMR:   Q8PPA8
- GeneID:   1154850
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0779
- NMPDR:   fig|190486.1.peg.775
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   XAXO190486:XAC0779-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 44117; Mature: 43986

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSANAAQAHAQPSAVLRPVMILAGGTGGHIFPGLAVAKVLRARGVPVTWLGADGAMET
CCCCCCHHHHHCCCHHHHCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCC
RLVPQHDIPIDTLAISGLRGKGVVKLLGAPVRVMRAVRAAGFVLRKRQPRAVISFGGFAA
CCCCCCCCCHHHHEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GPGGLAARLLGAPLLVHEQNRAPGMTNKVLSRFARRVLTGFPGSFVGEEAVGNPVRAEIA
CCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHH
ALPAPADRLFGRTGPVRVLVLGGSQGARVLNQALPAALVALGHSEVEVRHQCGEKLRAEA
CCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EAAYAQAGVNASVEPFIADMAAAYAWADLVVCRAGASTLAELCAAGVGSVLVPFAAAVDD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCC
HQTRNAEYLVGANAAVLLKQDDSLPVRLQQVLQTLLADPARRLSMANAARTLAKPDAAER
CCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHH
IADIILQEAGNGPSGMGNGHSSEQPQERTLMHADKRTDQVSVAAGAQLHTIPDSRFPIRT
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEC
STGGAR
CCCCCC
>Mature Secondary Structure 
SVSANAAQAHAQPSAVLRPVMILAGGTGGHIFPGLAVAKVLRARGVPVTWLGADGAMET
CCCCCHHHHHCCCHHHHCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCC
RLVPQHDIPIDTLAISGLRGKGVVKLLGAPVRVMRAVRAAGFVLRKRQPRAVISFGGFAA
CCCCCCCCCHHHHEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GPGGLAARLLGAPLLVHEQNRAPGMTNKVLSRFARRVLTGFPGSFVGEEAVGNPVRAEIA
CCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHH
ALPAPADRLFGRTGPVRVLVLGGSQGARVLNQALPAALVALGHSEVEVRHQCGEKLRAEA
CCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EAAYAQAGVNASVEPFIADMAAAYAWADLVVCRAGASTLAELCAAGVGSVLVPFAAAVDD
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHCC
HQTRNAEYLVGANAAVLLKQDDSLPVRLQQVLQTLLADPARRLSMANAARTLAKPDAAER
CCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHH
IADIILQEAGNGPSGMGNGHSSEQPQERTLMHADKRTDQVSVAAGAQLHTIPDSRFPIRT
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEC
STGGAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217