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The map label for this gene is ftsW [H]

Identifier: 21241548

GI number: 21241548

Start: 922497

End: 923873

Strand: Direct

Name: ftsW [H]

Synonym: XAC0778

Alternate gene names: 21241548

Gene position: 922497-923873 (Clockwise)

Preceding gene: 21241547

Following gene: 21241549

Centisome position: 17.82

GC content: 65.8

Gene sequence:

>1377_bases
ATGAACGACATGTCCCGCCAGGCAACACGACTGGACGCCATCGGCGGCCGCTACGACCCGTGGCTGCTCGGGGCCGCAGT
CACGCTCGCGTCGCTGGGTGTGGTGATGGTGGCGTCCAGCTCGATCGAGCTGGAAGCCAGCCCGTTCTACTACCTGACCC
GCCACCTGCTATTCCTGGGGGGCGGCATCGCGCTGGCGTTCTGGGCGATGCGCACCGAGCTCAAGACCATCGAACAGCAC
AACCAGATGTTGTTGCTGGCCTGCTTTGTGCTGCTCGTGGTGGTGTTCGTGCCTGGCCTGGGCAGCACCGTCAATGGCGC
CAAGCGCTGGATCAACCTGGGCGTATCGCGGTTCCAGGTGGTCGAATCGGTGAAGGTGTTCTACATCATCTGGCTGGCGA
GCTATCTGGTGCGTTTCCGCGACGAGGTCAACGCGACCTGGCAGGCGATGCTCAAACCGGTATTCGTGGTCGGCTTCCTG
GTCGGCCTGTTGCTGCTGCAGCCGGACTTCGGCTCCTCGATGCTGCTGCTGAGCGTGACCGCCTGCATGCTCGTGCTGGG
CGGTGCGCCGATCGGGCGCATCATCCTGCCGATCCTGCTGTTGCTGCCGGCCCTGGTGGCATTGGTGATCTTCGAGCCAT
ACCGCATGCGGCGCGTGACCTCCTTCATGGACCCGTGGGTAGATCAGCTGGGCTCCGGTTACCAGCTGTCCAACGCGCTG
ATGGCCATCGGCCGCGGCCAGTGGACCGGCGTGGGCCTGGGCGCTTCGGTACAGAAGCTCAACTACCTGCCCGAATCGCA
TACCGACTTCATCTTCTCGGTGATCGCCGAGGAACTGGGCTTTGTGGGCGTGTGCGGCGTGATCGGGCTATACGCGCTGC
TGGTCGGTCGCGCCTTCTGGCTGGGCATGCGCTGCGTGGAAATGAAGCGGCATTTCTCCGGCTACATCGCTTTCGGCATC
GGCCTGTGGATCGCGATGCAGAGCTTCGTGTCGATCGGCGTCAACCTGGGCATCCTGCCGACCAAGGGGCTGACCCTGCC
ACTGATTTCGTCAGGTGGCTCGTCGGTGCTGATGACCTGCCTTGCGATGGGCGTGCTGCTGCGTGTGTCCTACGAGGCCG
ATCGTGCCGAGCGCCTGCGCAGCAAGTTGTCTCCGCAGGGCGCGGCCAGCTCGCCAGCTGAGCCGGCCGAGCCGGTGGTC
GATTCGGTGCCGCCGGCGTACGCGCCTGCGCACAAGCCGCAGCGCGACACTGCCGTCGCGCCCGCACCGGCCGCCGCATC
GGTTGGCGCCGCCTACGTAGCGCCGGCGTCGGCCATCCTGCGCGGCACCAGCCGCATGCAACCGCGTGTGGAACCGACGT
TCGGGAGGATTGCGTGA

Upstream 100 bases:

>100_bases
TCGAGCTCAAGGGTTGGCCGGAGCCGCGCGTGATCGTGCGCTTCTGGATCATTTCGGTGGTGCTGGTGCTGATCGGCCTT
GCCACGTTGAAGGTGCGCTG

Downstream 100 bases:

>100_bases
GCGTTTCTGCCAATGCCGCGCAAGCGCACGCACAGCCATCTGCGGTGCTGCGGCCGGTCATGATTCTGGCCGGCGGCACC
GGCGGGCACATCTTCCCGGG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGFL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAASSPAEPAEPVV
DSVPPAYAPAHKPQRDTAVAPAPAAASVGAAYVAPASAILRGTSRMQPRVEPTFGRIA

Sequences:

>Translated_458_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGFL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAASSPAEPAEPVV
DSVPPAYAPAHKPQRDTAVAPAPAAASVGAAYVAPASAILRGTSRMQPRVEPTFGRIA
>Mature_458_residues
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLGGGIALAFWAMRTELKTIEQH
NQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQVVESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGFL
VGLLLLQPDFGSSMLLLSVTACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFWLGMRCVEMKRHFSGYIAFGI
GLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTCLAMGVLLRVSYEADRAERLRSKLSPQGAASSPAEPAEPVV
DSVPPAYAPAHKPQRDTAVAPAPAAASVGAAYVAPASAILRGTSRMQPRVEPTFGRIA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=44.3835616438356, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786853, Length=292, Percent_Identity=34.9315068493151, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 49323; Mature: 49323

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHC
GGIALAFWAMRTELKTIEQHNQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQV
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGFLVGLLLLQPDFGSSMLLLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFW
HHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LGMRCVEMKRHFSGYIAFGIGLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCHHHHHHH
LAMGVLLRVSYEADRAERLRSKLSPQGAASSPAEPAEPVVDSVPPAYAPAHKPQRDTAVA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
PAPAAASVGAAYVAPASAILRGTSRMQPRVEPTFGRIA
CCCCHHHCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNDMSRQATRLDAIGGRYDPWLLGAAVTLASLGVVMVASSSIELEASPFYYLTRHLLFLG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHC
GGIALAFWAMRTELKTIEQHNQMLLLACFVLLVVVFVPGLGSTVNGAKRWINLGVSRFQV
CHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VESVKVFYIIWLASYLVRFRDEVNATWQAMLKPVFVVGFLVGLLLLQPDFGSSMLLLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ACMLVLGGAPIGRIILPILLLLPALVALVIFEPYRMRRVTSFMDPWVDQLGSGYQLSNAL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
MAIGRGQWTGVGLGASVQKLNYLPESHTDFIFSVIAEELGFVGVCGVIGLYALLVGRAFW
HHHCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LGMRCVEMKRHFSGYIAFGIGLWIAMQSFVSIGVNLGILPTKGLTLPLISSGGSSVLMTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEECCCCHHHHHHH
LAMGVLLRVSYEADRAERLRSKLSPQGAASSPAEPAEPVVDSVPPAYAPAHKPQRDTAVA
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
PAPAAASVGAAYVAPASAILRGTSRMQPRVEPTFGRIA
CCCCHHHCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]