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The map label for this gene is amtB [H]

Identifier: 21240980

GI number: 21240980

Start: 252890

End: 254365

Strand: Direct

Name: amtB [H]

Synonym: XAC0206

Alternate gene names: 21240980

Gene position: 252890-254365 (Clockwise)

Preceding gene: 21240979

Following gene: 21240981

Centisome position: 4.89

GC content: 67.68

Gene sequence:

>1476_bases
ATGCGCTCTGACCCCACCAGCCCCGGAGTTCGTATGAAGACAGCTCTTTTTGCCGGGTGGAAAGCCCGGTTCTACAGCGT
GTGCATGCTGATGCTGTTCAGCGCGCTGATGGTGGGCGGCATGGGCAGTGCGCATGCGCAGTCCACGCCGCAGGTCACCC
CGCTGCCGACCGAGCCGGTCACCACCGAACCGCTGCCGTCGGCGCAGCCGGCCGCCCCGCCGGCCGCCGCCGCCGAAGCC
GCACCGGTCGTGGAGAAGGGCGATGTCGCCTGGATGCTGACCTCCACCTTGCTGGTGTTGCTGATGGTGGTGCCGGGCCT
TGCGCTGTTCTACGGCGGCATGGTGCGCGCCAAGAACGTGTTGTCGGTGCTGATCCAGGTGGCGGTGGTGTTCTCGCTGC
TGACCGTGCTGTGGGTGTTCTACGGCTACAGCCTGGCGTTCTCCGGCGAAGGCGCGTGGATCGGCAATCTGGACAAGGCG
TTGCTCAAGGGCGTCACCATCGAAACCCTGGCGGCGACCTTCACCAAGGGCGTGAGCCTGCCGGAATACGTGTTCGTGGC
GTTCCAGGCGACCTTCGCCGGCATCACCGGCGCGCTGATCGTGGGCGCCTTTGCCGAACGCGCCAAGTTCGCGGCGGTGC
TGCTGTTCTCGGCGATCTGGTTCACCTTCGGCTACCTGCCGCTGGCGCACATGGTCTGGGCCACCGGTGGGTATCTGTTC
GGGTTGGGCGCGTTGGATTTCGCCGGCGGCACCGTGGTGCATATCAACGCCGGCGTTGCCGGCCTGGTCGGCGCCTACTT
CGTCGGCAAGCGTGCCGGACTGGGACGTGAGGCGATCAAGCCGCACAACGTGACCCTGACCTTCGTCGGTGCCTCGCTGC
TGTGGGTGGGCTGGTTCGGCTTCAACGCCGGTTCCAACCTGGAAGCCAATGCCGGTGCGGCGCTGGCCTTCCTCAACACC
TTGCTGGCCACTGCCGCTGCCATCCTGGGCTGGTCGCTGACCGAGAAGATCATCAAGGGCAAGTCGTCCGCCCTGGGCGT
GGCCTCGGGCATGGTGGCCGGCCTGGTCGGCATCACCCCGGCCTGCGGCACGGTCGGCCCGTTCGGCGCGATCGTCATTG
GTCTGGCGGCCGGCGTACTGTGCGTGTGGGGCGTCACCGGCCTGAAGCGCCTGTTGGGCGCGGACGACAGCCTGGACGTG
TTCGGCGTGCATGGCCTGGGCGGCATCATCGGCGCCATCCTGACCGGTGTGTTCTCGGCGGCCTCGCTGGGCGGCCAGAA
GGGCGGCGATTACGACATCGTCCACCAGGTCGGCATCCAGGCGCTGGGCGTCGGGATCACGGTCGGCTGGATCGGCGTGG
TGTCGGTGGTGGGGTTCGTGGTTGCCAAGCTGGTGTTCGGCCTGCGCGTGAGCGAAGAAGCCGAGCGCGAGGGCCTGGAC
ATCACCTCGCACGGCGAAGCCGCGTACGAGTCGTGA

Upstream 100 bases:

>100_bases
ATCCAGAACGCCGCCGGCACCGGCAAGATCGGCGACGGCAAGATCTTCGTGACCGCGATCGAGCAGGTGGTGCGCATCCG
CACCGGCGAGATCGGCGCCG

Downstream 100 bases:

>100_bases
GCATGCACACCCGCGGCCGCGCTGCCGCGGGTGGCGCAACGACCCGGCCGGGAACGCCCAGCCGGGTCCGTTTTCCCCCG
TCGCCCGTTGGGCGCGGAAC

Product: ammonium transporter

Products: NH3 [Cytoplasm] [C]

Alternate protein names: Ammonia transporter [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MRSDPTSPGVRMKTALFAGWKARFYSVCMLMLFSALMVGGMGSAHAQSTPQVTPLPTEPVTTEPLPSAQPAAPPAAAAEA
APVVEKGDVAWMLTSTLLVLLMVVPGLALFYGGMVRAKNVLSVLIQVAVVFSLLTVLWVFYGYSLAFSGEGAWIGNLDKA
LLKGVTIETLAATFTKGVSLPEYVFVAFQATFAGITGALIVGAFAERAKFAAVLLFSAIWFTFGYLPLAHMVWATGGYLF
GLGALDFAGGTVVHINAGVAGLVGAYFVGKRAGLGREAIKPHNVTLTFVGASLLWVGWFGFNAGSNLEANAGAALAFLNT
LLATAAAILGWSLTEKIIKGKSSALGVASGMVAGLVGITPACGTVGPFGAIVIGLAAGVLCVWGVTGLKRLLGADDSLDV
FGVHGLGGIIGAILTGVFSAASLGGQKGGDYDIVHQVGIQALGVGITVGWIGVVSVVGFVVAKLVFGLRVSEEAEREGLD
ITSHGEAAYES

Sequences:

>Translated_491_residues
MRSDPTSPGVRMKTALFAGWKARFYSVCMLMLFSALMVGGMGSAHAQSTPQVTPLPTEPVTTEPLPSAQPAAPPAAAAEA
APVVEKGDVAWMLTSTLLVLLMVVPGLALFYGGMVRAKNVLSVLIQVAVVFSLLTVLWVFYGYSLAFSGEGAWIGNLDKA
LLKGVTIETLAATFTKGVSLPEYVFVAFQATFAGITGALIVGAFAERAKFAAVLLFSAIWFTFGYLPLAHMVWATGGYLF
GLGALDFAGGTVVHINAGVAGLVGAYFVGKRAGLGREAIKPHNVTLTFVGASLLWVGWFGFNAGSNLEANAGAALAFLNT
LLATAAAILGWSLTEKIIKGKSSALGVASGMVAGLVGITPACGTVGPFGAIVIGLAAGVLCVWGVTGLKRLLGADDSLDV
FGVHGLGGIIGAILTGVFSAASLGGQKGGDYDIVHQVGIQALGVGITVGWIGVVSVVGFVVAKLVFGLRVSEEAEREGLD
ITSHGEAAYES
>Mature_491_residues
MRSDPTSPGVRMKTALFAGWKARFYSVCMLMLFSALMVGGMGSAHAQSTPQVTPLPTEPVTTEPLPSAQPAAPPAAAAEA
APVVEKGDVAWMLTSTLLVLLMVVPGLALFYGGMVRAKNVLSVLIQVAVVFSLLTVLWVFYGYSLAFSGEGAWIGNLDKA
LLKGVTIETLAATFTKGVSLPEYVFVAFQATFAGITGALIVGAFAERAKFAAVLLFSAIWFTFGYLPLAHMVWATGGYLF
GLGALDFAGGTVVHINAGVAGLVGAYFVGKRAGLGREAIKPHNVTLTFVGASLLWVGWFGFNAGSNLEANAGAALAFLNT
LLATAAAILGWSLTEKIIKGKSSALGVASGMVAGLVGITPACGTVGPFGAIVIGLAAGVLCVWGVTGLKRLLGADDSLDV
FGVHGLGGIIGAILTGVFSAASLGGQKGGDYDIVHQVGIQALGVGITVGWIGVVSVVGFVVAKLVFGLRVSEEAEREGLD
ITSHGEAAYES

Specific function: Involved in the uptake of ammonia [H]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=425, Percent_Identity=54.3529411764706, Blast_Score=436, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17550182, Length=435, Percent_Identity=29.1954022988506, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550180, Length=435, Percent_Identity=28.5057471264368, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564042, Length=440, Percent_Identity=27.7272727272727, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI133931100, Length=450, Percent_Identity=24.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325396, Length=419, Percent_Identity=36.2768496420048, Blast_Score=237, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6321559, Length=449, Percent_Identity=34.075723830735, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6324187, Length=406, Percent_Identity=37.192118226601, Blast_Score=224, Evalue=2e-59,
Organism=Drosophila melanogaster, GI161078314, Length=418, Percent_Identity=28.2296650717703, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 50289; Mature: 50289

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS01219 AMMONIUM_TRANSP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCC
>Mature Secondary Structure
MRSDPTSPGVRMKTALFAGWKARFYSVCMLMLFSALMVGGMGSAHAQSTPQVTPLPTEPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TTEPLPSAQPAAPPAAAAEAAPVVEKGDVAWMLTSTLLVLLMVVPGLALFYGGMVRAKNV
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSVLIQVAVVFSLLTVLWVFYGYSLAFSGEGAWIGNLDKALLKGVTIETLAATFTKGVSL
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEECCHHHHHHCCCHHHHHHHHHHCCCCC
PEYVFVAFQATFAGITGALIVGAFAERAKFAAVLLFSAIWFTFGYLPLAHMVWATGGYLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
GLGALDFAGGTVVHINAGVAGLVGAYFVGKRAGLGREAIKPHNVTLTFVGASLLWVGWFG
ECCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHC
FNAGSNLEANAGAALAFLNTLLATAAAILGWSLTEKIIKGKSSALGVASGMVAGLVGITP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
ACGTVGPFGAIVIGLAAGVLCVWGVTGLKRLLGADDSLDVFGVHGLGGIIGAILTGVFSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHH
ASLGGQKGGDYDIVHQVGIQALGVGITVGWIGVVSVVGFVVAKLVFGLRVSEEAEREGLD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
ITSHGEAAYES
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]