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The map label for this gene is bdlA [H]

Identifier: 57237992

GI number: 57237992

Start: 1169571

End: 1170860

Strand: Reverse

Name: bdlA [H]

Synonym: CJE1253

Alternate gene names: 57237992

Gene position: 1170860-1169571 (Counterclockwise)

Preceding gene: 57237993

Following gene: 57237978

Centisome position: 65.86

GC content: 31.47

Gene sequence:

>1290_bases
ATGTTTGGTGCTAAGAAAAATAATACTAAAATAATTGAACAACTTGAAAAAAAATGTAATGGTTTAGGAGATATTTTAAG
ATCTATTGGGAATACCATGGCGGTAATTGAATTTACTACCGATGGCGTTATTTTAGAGGCAAATCAAAATTTTTTAACAA
CTATGAAATACTCCCTTTCAGAGATCAAGGGTAAGCATCATAGTATGTTTTGTTTGCCTGAAGTTGTTAATTCTTCAGCA
TATAGTGATTTTTGGAAAGATTTAAGAGATGGAAAAGCTAGAAGTGGTCTTTTTAGACGTATAGCTAAGGGAGGGATAGA
TGTTTATTTAGAAGCAAATTATCTTCCAATTAGTGATAATAATGGTCATGTTTATAAAATTATTAAATTTGCCAATGATA
TAACTCAAAGACATTATGAAATGCTTGATCTTAGAAATACTATTGCTGCTGCTAATCGTTCTATGGCTATTATTGAATTT
AAACCTGATGGGACTATTATTACGGCTAATGAAAATTTTTTAAGAACTATGGATTTTAATATTGATGAGATTAAAGGAAA
GCATCATAGCATGTTCTGTGATTCTAATTATAGACACTCTAAGGACTATGTTCAATTTTGGGAAGATTTAAGAGAGGGCA
AATTTCAATCAGGTAAATATATAAGATACGGAAGAAATAATAAAAAAGTATACCTTGAAGCAAGTTATAATCCGGTTAAA
AATGATGATGGAAAAATTTACAAGGTTATTAAATTTGCTACAGATATAAGCGAACAAGTTAAAAAAGATCAAGAAAAACT
TTGCCTCATAAGCGAACTTGCAGAAAAAAATGATAATCTTACTCAAGATGGAGATCGTGTAATTGAAAACACTGTTTCAA
ATGTTCAGAATATTGCTGATATGATGTCTCAAAGTTCAAATCTTGTTTCCTCATTAAATCAACAATCAGATGAAATTAAA
TCTATTATTCAGACTATTAGTGATATCGCTGATCAAACTAATCTGCTTGCTTTAAATGCTGCTATTGAGGCAGCACGTGC
TGGTGAACATGGTAGAGGCTTTGCTGTTGTTGCTGATGAAGTAAGAAATTTAGCTGAAAGAACAGGGCATTCGGTTAATG
AAATTACCACTACGATTAATTCTATTCGTAATGTTACATCACAAGTGGTTGAGAGTATTAAAAGCGGTTTAGAGGATGTT
AATCAGAGTGTTGAACTTGCAAAAGAAGCAAGAGAGTGTATGGAGAAAATTCGTGAAAGCTCTGCTGAAGTTGCTAAAGC
GATGTCATAA

Upstream 100 bases:

>100_bases
AGGATATATTTAACTTATAAATTAATATAATTTTAAGTAAATAATACTATATAAATATGATATAATTTTAAAATAATTTA
TTATTAAAAAGGTGAGTTTT

Downstream 100 bases:

>100_bases
GCGTGATTTTCACGCTTATTTTTAAGTAATTAAATCTTTAAAATTTTTAAAACCACTTTCTTGATTGCATTTTTCTTTTA
AAATATTTAAAAATTCTTTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFGAKKNNTKIIEQLEKKCNGLGDILRSIGNTMAVIEFTTDGVILEANQNFLTTMKYSLSEIKGKHHSMFCLPEVVNSSA
YSDFWKDLRDGKARSGLFRRIAKGGIDVYLEANYLPISDNNGHVYKIIKFANDITQRHYEMLDLRNTIAAANRSMAIIEF
KPDGTIITANENFLRTMDFNIDEIKGKHHSMFCDSNYRHSKDYVQFWEDLREGKFQSGKYIRYGRNNKKVYLEASYNPVK
NDDGKIYKVIKFATDISEQVKKDQEKLCLISELAEKNDNLTQDGDRVIENTVSNVQNIADMMSQSSNLVSSLNQQSDEIK
SIIQTISDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAERTGHSVNEITTTINSIRNVTSQVVESIKSGLEDV
NQSVELAKEARECMEKIRESSAEVAKAMS

Sequences:

>Translated_429_residues
MFGAKKNNTKIIEQLEKKCNGLGDILRSIGNTMAVIEFTTDGVILEANQNFLTTMKYSLSEIKGKHHSMFCLPEVVNSSA
YSDFWKDLRDGKARSGLFRRIAKGGIDVYLEANYLPISDNNGHVYKIIKFANDITQRHYEMLDLRNTIAAANRSMAIIEF
KPDGTIITANENFLRTMDFNIDEIKGKHHSMFCDSNYRHSKDYVQFWEDLREGKFQSGKYIRYGRNNKKVYLEASYNPVK
NDDGKIYKVIKFATDISEQVKKDQEKLCLISELAEKNDNLTQDGDRVIENTVSNVQNIADMMSQSSNLVSSLNQQSDEIK
SIIQTISDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAERTGHSVNEITTTINSIRNVTSQVVESIKSGLEDV
NQSVELAKEARECMEKIRESSAEVAKAMS
>Mature_429_residues
MFGAKKNNTKIIEQLEKKCNGLGDILRSIGNTMAVIEFTTDGVILEANQNFLTTMKYSLSEIKGKHHSMFCLPEVVNSSA
YSDFWKDLRDGKARSGLFRRIAKGGIDVYLEANYLPISDNNGHVYKIIKFANDITQRHYEMLDLRNTIAAANRSMAIIEF
KPDGTIITANENFLRTMDFNIDEIKGKHHSMFCDSNYRHSKDYVQFWEDLREGKFQSGKYIRYGRNNKKVYLEASYNPVK
NDDGKIYKVIKFATDISEQVKKDQEKLCLISELAEKNDNLTQDGDRVIENTVSNVQNIADMMSQSSNLVSSLNQQSDEIK
SIIQTISDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAERTGHSVNEITTTINSIRNVTSQVVESIKSGLEDV
NQSVELAKEARECMEKIRESSAEVAKAMS

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=175, Percent_Identity=37.1428571428571, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367378, Length=152, Percent_Identity=39.4736842105263, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789453, Length=117, Percent_Identity=42.7350427350427, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788194, Length=107, Percent_Identity=43.9252336448598, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787690, Length=129, Percent_Identity=37.984496124031, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48302; Mature: 48302

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGAKKNNTKIIEQLEKKCNGLGDILRSIGNTMAVIEFTTDGVILEANQNFLTTMKYSLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHH
EIKGKHHSMFCLPEVVNSSAYSDFWKDLRDGKARSGLFRRIAKGGIDVYLEANYLPISDN
HHCCCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECEEEECCC
NGHVYKIIKFANDITQRHYEMLDLRNTIAAANRSMAIIEFKPDGTIITANENFLRTMDFN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEEECCC
IDEIKGKHHSMFCDSNYRHSKDYVQFWEDLREGKFQSGKYIRYGRNNKKVYLEASYNPVK
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCC
NDDGKIYKVIKFATDISEQVKKDQEKLCLISELAEKNDNLTQDGDRVIENTVSNVQNIAD
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
MMSQSSNLVSSLNQQSDEIKSIIQTISDIADQTNLLALNAAIEAARAGEHGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHH
VRNLAERTGHSVNEITTTINSIRNVTSQVVESIKSGLEDVNQSVELAKEARECMEKIRES
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEVAKAMS
HHHHHHHCC
>Mature Secondary Structure
MFGAKKNNTKIIEQLEKKCNGLGDILRSIGNTMAVIEFTTDGVILEANQNFLTTMKYSLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCHHHHHHHHHH
EIKGKHHSMFCLPEVVNSSAYSDFWKDLRDGKARSGLFRRIAKGGIDVYLEANYLPISDN
HHCCCCCCEEECHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECEEEECCC
NGHVYKIIKFANDITQRHYEMLDLRNTIAAANRSMAIIEFKPDGTIITANENFLRTMDFN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEEECCC
IDEIKGKHHSMFCDSNYRHSKDYVQFWEDLREGKFQSGKYIRYGRNNKKVYLEASYNPVK
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCC
NDDGKIYKVIKFATDISEQVKKDQEKLCLISELAEKNDNLTQDGDRVIENTVSNVQNIAD
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
MMSQSSNLVSSLNQQSDEIKSIIQTISDIADQTNLLALNAAIEAARAGEHGRGFAVVADE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHH
VRNLAERTGHSVNEITTTINSIRNVTSQVVESIKSGLEDVNQSVELAKEARECMEKIRES
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAEVAKAMS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]