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The map label for this gene is pgsA [H]

Identifier: 57237949

GI number: 57237949

Start: 1128920

End: 1129456

Strand: Direct

Name: pgsA [H]

Synonym: CJE1210

Alternate gene names: 57237949

Gene position: 1128920-1129456 (Clockwise)

Preceding gene: 57238716

Following gene: 57237950

Centisome position: 63.5

GC content: 29.98

Gene sequence:

>537_bases
ATGAATTTACCCAATATCTTGGCGATTTTTAGAATGGTTTTAGCGCCTTTGCTATTTTTTTTATTAATTCATCATTTTGA
AAATATTCATCAAAGTTGGATTAACTATTTTGCTGCTTTAACTTTTTCATTAGCAGCTTTAAGTGATTTTTTTGATGGAT
ACATCGCAAGAACTTGGAAACAAACTACAAAACTGGGTGGAATCTTAGATCCATTAGCCGATAAAATGCTTGTTTTAGCA
GCTTTTTTAGGGCTTTTACTTACAGGAAAAGCTAATGAATGGGTAATTTATATTATATTAGTAAGGGAATTTTTTATCAC
AGGTTTTAGAGTTGTAATGATTAGCGAAAATTTAAATGTCAATGCTTCTTTTGCAGGCAAACTTAAAACCGCTTTTCAAA
TGACTGCGATAGGATTTTTAATCATGGAGTGGATAGGCGGTGAAATTCTACTTTACATAGCTTTGATTTTAACTCTTTAT
TCTGGATTTGAATACATCTATACTTATATAAAAGCTCAAAAAAAAGGAGAAAAATGA

Upstream 100 bases:

>100_bases
TAAAAATAAACTGATTCTTTTTTTGTATTTTTACTAAGTCTTTGCTTAAATTTTATACAATTTTGATTATAATTTTACAT
TTAATTTCACAAGGCTTGTT

Downstream 100 bases:

>100_bases
GATCTTTATTATTTTTAATTGTTATTTTGATTTTGGGAATTAAATTTTATTCTATTGAATTTTTAGCAACTGTTTTAGTC
ATCTCATTTTTAATTTTCTT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MNLPNILAIFRMVLAPLLFFLLIHHFENIHQSWINYFAALTFSLAALSDFFDGYIARTWKQTTKLGGILDPLADKMLVLA
AFLGLLLTGKANEWVIYIILVREFFITGFRVVMISENLNVNASFAGKLKTAFQMTAIGFLIMEWIGGEILLYIALILTLY
SGFEYIYTYIKAQKKGEK

Sequences:

>Translated_178_residues
MNLPNILAIFRMVLAPLLFFLLIHHFENIHQSWINYFAALTFSLAALSDFFDGYIARTWKQTTKLGGILDPLADKMLVLA
AFLGLLLTGKANEWVIYIILVREFFITGFRVVMISENLNVNASFAGKLKTAFQMTAIGFLIMEWIGGEILLYIALILTLY
SGFEYIYTYIKAQKKGEK
>Mature_178_residues
MNLPNILAIFRMVLAPLLFFLLIHHFENIHQSWINYFAALTFSLAALSDFFDGYIARTWKQTTKLGGILDPLADKMLVLA
AFLGLLLTGKANEWVIYIILVREFFITGFRVVMISENLNVNASFAGKLKTAFQMTAIGFLIMEWIGGEILLYIALILTLY
SGFEYIYTYIKAQKKGEK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=151, Percent_Identity=31.1258278145695, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI10092647, Length=151, Percent_Identity=31.1258278145695, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=35.7954545454545, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20291; Mature: 20291

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNILAIFRMVLAPLLFFLLIHHFENIHQSWINYFAALTFSLAALSDFFDGYIARTWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTTKLGGILDPLADKMLVLAAFLGLLLTGKANEWVIYIILVREFFITGFRVVMISENLNV
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
NASFAGKLKTAFQMTAIGFLIMEWIGGEILLYIALILTLYSGFEYIYTYIKAQKKGEK
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLPNILAIFRMVLAPLLFFLLIHHFENIHQSWINYFAALTFSLAALSDFFDGYIARTWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTTKLGGILDPLADKMLVLAAFLGLLLTGKANEWVIYIILVREFFITGFRVVMISENLNV
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
NASFAGKLKTAFQMTAIGFLIMEWIGGEILLYIALILTLYSGFEYIYTYIKAQKKGEK
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA