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The map label for this gene is purL [H]

Identifier: 57237783

GI number: 57237783

Start: 972979

End: 975165

Strand: Reverse

Name: purL [H]

Synonym: CJE1035

Alternate gene names: 57237783

Gene position: 975165-972979 (Counterclockwise)

Preceding gene: 57237784

Following gene: 57237782

Centisome position: 54.85

GC content: 35.48

Gene sequence:

>2187_bases
ATGGACAAAGAAACCATAAAAGCACACAAAATTAGCGATGAAGAATATACACAAATTTTAGAAATTTTAGGACGTGAGCC
AAATTTATTAGAGCTTGGGGTTATTTCTGCGATGTGGAGTGAGCATTGCTCTTATAAATCTAGTAAAAAATATCTTAATG
GTTTTCCAACTAAAGCACCTTGGGTGATTCAAGGCCCAGGTGAAAATGCAGGGGTTATTGATATCGGGCAAGGTATGGCA
GCAGTTTTTAAAGTAGAAAGTCACAATCACCCTAGCTTTATTGAACCTTTTGCAGGTGCGGCTACAGGAGTAGGGGGAAT
TTTACGTGATGTTTTTACTATGGGTGCAAGAGTGGTTGCAGGGCTAAATTCTTTAAAATTTGGCAATATTCATAATGAAA
AATGCAGCAAACATCAAAAATACCTTGTTAAAGGTGTGGTAAATGGAATTTCTCATTATGGAAATTGCATGGGTGTGCCA
ACTATAGGTGGAGAATGTGCTTTTGATGAGTGTTTTAATGGAAATATCTTAGTTAATGCCTTTGCTTTAGGGGTTTGTAA
AAGTGAAGATATCTTTTATGCTAAGGCTGAAGGTGTAGGAAATCCTGTGATTTATGTGGGTTCAAAAACAGGGCGTGATG
GACTTGGTGGAGCGGTTATGGCAAGTGATAGCTTCAATGAAGAAAGCAAATCTTTGCGTCCTACAGTGCAAATTGGCGAT
CCTTTCAGTGAAAAACTTCTTATGGAAGCTTGTTTAGAGCTTTTTAAAACTGATTATATTGTGGGTATTCAAGATATGGG
TGCTGCAGGGCTTACTTCAAGTTCTTTTGAAATGGCAGGAAGAAGTGGCAGTGGCATGAAACTTTACTTAGATAAAACTC
CTATACGTGAAAGCGGTATGACTCCTTATGAGTTAATGCTTAGCGAGTCTCAAGAAAGAATGCTTATTTGTGCGAAAAAA
GGCTATGAAGATAAGGTTATAGAAATTTTCAAAAAATGGGATTTAGATGCTGTGGTTATAGGTGAAGTTACCAATACAGG
AAAAATGGAGCTTTTTTGGCATGATGAGCTTGTAGGGCTTATTCCTATCGAGCCTCTAAGTGAAAAAGCGCCGATTTTAA
GTCGTCCTATAAGTGAGCCAAAATATTTAAGTGAAATTAAAGATTATAAATTTGAGTTAAAATTAAGCATTCAAGAGCTT
TTTATACAAATGCTTCAAAATGAAAATATTAACAACAAAGCTTTTATTTATGATCAATTTGATTCAAGTGTGCAAACCAA
TACTATAAAAGCTGATGGAAGATTAGGTGCTAGTGCCATTCGTATCAAAGAAAATGGTGCAAGTGTGGCTATGGCTATAG
AATGTAACTCACGCTTAAATTATGTAAATCCTAAAATAGGAGCAGCTTTAGCAGTAGCTTCAGCAGGAAGAAAAGTTGCT
TGCACGGGGGCTAAGCCTTTGGCAATAAGTGATTGTTTAAATTATGGAAATCCGCAAAATCCTGAAGTGATGTGGCAATT
TGCACAAGGTTGCGAAGGCATTAAAGAAGCTTGTAAAGAGTTAAATACCCCAGTAGTAAGCGGCAATGTTTCACTTTATA
ATGAAACTGAAGGCGTAAGTATTTATCCAAGTCCTACTATAGTAAGCGTAGGGGTTTTAGAAGATGCAAATAAAACCTTA
AAAGCTAGTTTTGAAAAAGAAAATTTAAGTGTTTATCTTTTGGGTGAAAGTTTAGGGGAATTTGGTGGATCTATGGTAAT
GAAAATCCAAGATAAAAAAGTATCAGGAAGTCTTAAAGAGCTTGATTATAAAGCTGAAATTGCACTTTGGGATTTGCTTT
ATAAAGCCAATCAAAATTCTTTACTTGAGTGTGCCAATAGCGTAGGAATAGGGGGTATTGCTATGACTTTGGCAAAAATG
TTTGCTATTTCTAGTGTAGGTGCAAATTTAACAAGTGGTTTTGATGATGAAAAAATGATTTTTGATGAGAGTGCAAGTCG
TGCTATAGTAGGGCTTAGTAAAGAAAATGAAGAAGCTTTTTTAAATTTAGCCAAAGAATTTGGAGTAAAAGCTTATAAAT
TAGGTGTGAGTACTAGCCAAAAACATTTTAAACTTGATAGCATTGAGTTAAGCAAGGCTGAACTTGATAAGCTTTATTTT
GAAAGTTTTAAAGAGCAAATCCAATGA

Upstream 100 bases:

>100_bases
GCGATTAATGAACTTGCAAGATTTACCAAAGATTTTCAAAGAGATGAAATTTTAGACGAAATGTTTGGTAATTTTTGTTT
AGGAAAATGAAAGGATAAAA

Downstream 100 bases:

>100_bases
CTTTAGTTTTAATTATACTCGTTGTTTTGGTGTTTTACTGGTATTATAAAACTTGGGGAAAACAGGATTTTTTAAACTCA
GCTACAAGAGGAGCCAAAGG

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMA
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGLIPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYF
ESFKEQIQ

Sequences:

>Translated_728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMA
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGLIPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYF
ESFKEQIQ
>Mature_728_residues
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMA
AVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVP
TIGGECAFDECFNGNILVNAFALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGMTPYELMLSESQERMLICAKK
GYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGLIPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQEL
FIQMLQNENINNKAFIYDQFDSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTL
KASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKM
FAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYF
ESFKEQIQ

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=787, Percent_Identity=23.7611181702668, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17553022, Length=377, Percent_Identity=25.1989389920424, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=537, Percent_Identity=24.9534450651769, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 79266; Mature: 79266

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
WVIQGPGENAGVIDIGQGMAAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVA
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCCCEEEEE
FALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
EEEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHCCCCEEEECC
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGM
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCC
TPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGL
CHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCEEEE
IPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQELFIQMLQNENINNKAFIYDQF
ECCCCCCCCCCHHHCCCCCCHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCCEEEEEECC
DSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CCCCCCCEEEECCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEE
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVS
ECCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEE
IYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKE
ECCCCCEEEEEEECCCCCHHEECCCCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCHHH
LDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSGFDDEKMI
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEE
FDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYF
ECCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEECCEECCHHHHHHHHH
ESFKEQIQ
HHHHHHCC
>Mature Secondary Structure
MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHCCCCCCCC
WVIQGPGENAGVIDIGQGMAAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVA
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHCCCCEEEEE
FALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGD
EEEEEECCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHCCCCEEEECC
PFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGM
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCC
TPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGL
CHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCEEEE
IPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQELFIQMLQNENINNKAFIYDQF
ECCCCCCCCCCHHHCCCCCCHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCCEEEEEECC
DSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVA
CCCCCCCEEEECCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEE
CTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVS
ECCCCCEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEE
IYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKE
ECCCCCEEEEEEECCCCCHHEECCCCCCCEEEEEECHHHHCCCEEEEEEECCCCCCCHHH
LDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSGFDDEKMI
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEE
FDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYF
ECCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEECCEECCHHHHHHHHH
ESFKEQIQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA